Aging News and Research

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Changes in daily activity patterns may help predict cognitive decline in older adults

Wearable movement-tracking devices may someday be useful in providing early warnings of cognitive decline among older adults, suggest new findings from researchers at the Johns Hopkins Bloomberg School of Public Health.

20 Jul 2022

Caregiver engagement holds potential for improving patient outcomes

Led by Regenstrief Institute Research Scientist Kristin Levoy, PhD, MSN, R.N., a meta-analysis of findings from 54 studies (involving more than 31,000 individuals) confirms that caregiver engagement across healthcare transitions (for example from hospital to home) of chronically ill adults is instrumental in preventing rehospitalizations, and holds potential for enhancing other patient outcomes.

19 Jul 2022

Elephant genes could offer new clues to preventing cancer development

Scientists modeling the cancer-suppressing p53 gene identify how the 20 different molecules unique to elephants get activated for increased sensitivity and response against carcinogenic conditions - with implications for cancer treatments in humans.

19 Jul 2022

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia.

19 Jul 2022

Sex matters when it comes to immune responses to vaccines and viral infections

A review published in Frontiers in Aging analyzed the sex differences in the safety, effectiveness, and immunogenicity of influenza and COVID-19 vaccines in older individuals. It also analyzed the way sex brings about the modification of the impact of age-related factors on vaccination.

18 Jul 2022

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders.

18 Jul 2022

New method could facilitate the diagnosis of early-stage Parkinson's disease

Parkinson's is a progressive and debilitating disease of the brain that eventually compromises patients' ability to walk and even to talk. Its diagnosis is complex, and in the early stages – impossible.

15 Jul 2022

Texas Biomed professor to join $577 million effort for developing antivirals against COVID-19 and other viruses

As the coronavirus waves keep coming and cases are on the rise once again, the National Institutes of Health (NIH) recently launched a $577 million effort to develop antivirals against COVID-19 and other viruses with high pandemic potential.

15 Jul 2022

Alcohol consumption does not provide any health benefits, presents many risks for young people

Young people face higher health risks from alcohol consumption than older adults, according to a new analysis published in The Lancet.

15 Jul 2022

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

research group led by Dr. Soichi Sano, a specially appointed lecturer in the Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka Metropolitan University, revealed that men with hematopoietic mosaic loss of Y chromosome (mLOY) — meaning men with an increase, in the blood, of cells that have lost the male sex chromosome — have a worse prognosis for heart failure due to fibrosis progression in the heart.

15 Jul 2022

Exploring the connection between Parkinson's disease and gut microbiota to uncover potential therapeutic targets

Scientists have published a new review focusing on the relationship between PD and gut microbiota.

15 Jul 2022

New tool uses existing EHR data to identify avoidable hospital transfers of nursing home residents

The Avoidable Transfer Scale, an innovative tool that uses data commonly included in a nursing home resident's electronic health record to identify and characterize potentially avoidable hospitalizations, highlights issues that can be handled in the nursing home itself.

15 Jul 2022

Mosaic loss of Y chromosome increases risk for heart failure and cardiac fibrosis in men

Why a condition that frequently occurs in aging men, in which an increasing number of hematopoietic cells display a loss of the Y chromosome, is associated with increased risk of mortality and age-related diseases is now a little clearer, thanks to work in mice.

15 Jul 2022

Y chromosome loss in men can lead to deadly heart failure, research shows

The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows.

14 Jul 2022

Age-related increases in brain inflammation may link Alzheimer's disease risk with sleep disturbance

A multisite research team from the University of California, Irvine, the University of Wisconsin–Madison and Wake Forest University has discovered that brain inflammation may link Alzheimer's disease risk with sleep disturbance, which may aid early detection and prevention efforts by identifying novel treatment targets at preclinical stages.

13 Jul 2022

New underlying cause of Wiskott-Aldrich syndrome discovered

Researchers at the Salk Institute and King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have discovered a new underlying cause of Wiskott-Aldrich syndrome, a rare genetic disease that leads to bleeding and immune deficiencies in babies.

13 Jul 2022

New high-throughput genomic array offers an in-depth view of the mouse epigenome

A new high-throughput genomic array offers an unprecedented look into the mouse epigenome, giving researchers an in-depth view into the basis of health and disease in a vital model organism.

13 Jul 2022

Lifestyle factors may be more important than age in determining a person's cognitive function

Individuals with no dementia risk factors, such as smoking, diabetes or hearing loss, have similar brain health as people who are 10 to 20 years younger than them, according to a new Baycrest study. The study found that a single dementia risk factor could reduce cognition by the equivalent of up to three years of aging.

13 Jul 2022

Study confirms a causal link between lead-in-water and adverse fetal health outcomes

Lehigh University and Bentley University health economics researchers have published the first study to confirm a causal relationship between lead-in-water and adverse fetal health outcomes.

13 Jul 2022

Diversifying STEM; the Importance of Representation, Equity, and Inclusion

As part of our SLAS Europe 2022 coverage, we speak to Paula Petrone, Associate Research Professor at ISGlobal, about the importance of representation, inclusion, and equity in the STEM fields.

From Society for Laboratory Automation and Screening (SLAS) 13 Jul 2022

Aging News and Research

Changes in daily activity patterns may help predict cognitive decline in older adults

Caregiver engagement holds potential for improving patient outcomes

Elephant genes could offer new clues to preventing cancer development

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Sex matters when it comes to immune responses to vaccines and viral infections

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

New method could facilitate the diagnosis of early-stage Parkinson's disease

Texas Biomed professor to join $577 million effort for developing antivirals against COVID-19 and other viruses

Alcohol consumption does not provide any health benefits, presents many risks for young people

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

Exploring the connection between Parkinson's disease and gut microbiota to uncover potential therapeutic targets

New tool uses existing EHR data to identify avoidable hospital transfers of nursing home residents

Mosaic loss of Y chromosome increases risk for heart failure and cardiac fibrosis in men

Y chromosome loss in men can lead to deadly heart failure, research shows

Age-related increases in brain inflammation may link Alzheimer's disease risk with sleep disturbance

New underlying cause of Wiskott-Aldrich syndrome discovered

New high-throughput genomic array offers an in-depth view of the mouse epigenome

Lifestyle factors may be more important than age in determining a person's cognitive function

Study confirms a causal link between lead-in-water and adverse fetal health outcomes

Diversifying STEM; the Importance of Representation, Equity, and Inclusion

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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