Clinical Trial News and Research

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Retinoid therapy improves vision in mice with Usher syndrome

Using data generated from patients and mice with genetic mutation for the disorder Usher syndrome, researchers from the University of Maryland School of Medicine, the National Institutes of Health's National Eye Institute, and National Institute on Deafness and Other Communication Disorders, documented the natural history of vision impairment in patients and identified the cell mechanism behind progressive vision loss.

9 Nov 2021

Proton therapy used for the first time in Switzerland to treat lung cancer

Today a 60-year-old patient suffering from lung cancer received proton beam therapy, a medical procedure where positively charged particles are precisely targeted at the tumor. This is the first time this type of radiotherapy has been used for lung cancer treatment in Switzerland.

9 Nov 2021

Repeated listening to favorite music induces beneficial brain plasticity in Alzheimer’s patients

Researchers at the University of Toronto and Unity Health Toronto have demonstrated that repeated listening to personally meaningful music induces beneficial brain plasticity in patients with mild cognitive impairment or early Alzheimer's disease.

9 Nov 2021

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Cancer patients who are ineligible for clinical trials receive immune checkpoint inhibitors (ICI) at greater rates than patients who are trial eligible despite no survival benefit, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

9 Nov 2021

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Leonard Imbula of the Healthy Mind Lab at Washington University School of Medicine in St. Louis holds a bottle of fluvoxamine, a psychiatric drug that has been shown, in a pair of studies conducted on two continents, to be an effective treatment for people sick with COVID-19.

9 Nov 2021

Exercise can alleviate symptoms of anxiety, study shows

Both moderate and strenuous exercise alleviate symptoms of anxiety, even when the disorder is chronic, a study led by researchers at the University of Gothenburg shows.

9 Nov 2021

COVID-19 drug candidate with wide-ranging antiviral activity

A new study investigated the antiviral activity and mechanism of action of Brilacidin against multiple human coronaviruses.

9 Nov 2021

Novel study aims to develop personalized treatment for triple-negative breast cancer

Indiana University School of Medicine researcher Bryan P. Schneider, MD, is leading a novel nationwide study to better understand how to treat patients with triple-negative breast cancer based on their own unique genetic data.

8 Nov 2021

Clinical trial compares Amulet with Watchman FLX device for percutaneous left atrial appendage closure

SWISS-APERO is the first randomized clinical trial comparing Amulet with the new generation Watchman FLX device in terms of residual left atrial appendage (LAA) patency after percutaneous LAA closure (LAAC) as evaluated by 45-day cardiac computed tomography angiography (CCTA).

8 Nov 2021

International Alzheimer’s trial to evaluate a combination of drugs targeting two brain proteins

Trial participant Rachel Habiger meets in 2018 with Randall J. Bateman, MD, the director of the Dominantly Inherited Alzheimer Network Trials Unit at Washington University School of Medicine in St. Louis.

8 Nov 2021

Study points to a new, effective treatment option for patients with mesothelioma

Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

8 Nov 2021

Diabetes medication reduces the rate of kidney function decline in CKD patients

Clinical trial data reveal that dapagliflozin - a sodium-glucose cotransporter 2 inhibitor prescribed to treat diabetes - reduces the rate of kidney function decline in patients with chronic kidney disease (CKD). The findings will be presented at ASN Kidney Week 2021 November 4–November 7.

7 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Anemia is a common and sometimes debilitating problem among patients with chronic kidney disease (CKD). Anemia can occur when the kidneys become damaged, limiting the production of erythropoietin (EPO) - a hormone that signals to the body to make red blood cells.

7 Nov 2021

New type of COVID vaccine potentially easier to produce and does not need refrigeration

Currently available COVID vaccines require cold storage and sophisticated manufacturing capacity, which makes it difficult to produce and distribute them widely, especially in less developed countries.

6 Nov 2021

Researchers use suction method to deliver SARS-CoV-2 DNA vaccine in lab tests

Rutgers researchers studying COVID-19 have created a new way to deliver DNA molecules into skin cells, using a suction technique similar to the ancient healing practice of cupping.

6 Nov 2021

Ibrutinib plus standard chemotherapy effective in younger patients with diffuse large B-cell lymphoma

Younger patients with specific genetic subtypes of non-GCB DLBCL, called MCD and N1, had an exceptional response to the treatment combination.

5 Nov 2021

MHRA approves first oral antiviral for the treatment of COVID-19

The antiviral Lagevrio (molnupiravir) is safe and effective at reducing the risk of hospitalization and death in people with mild to moderate COVID-19 who are at increased risk of developing severe disease, the Medicines and Healthcare products Regulatory Agency announced today.

4 Nov 2021

Clear communication needed with college students regarding COVID-19 vaccine procedures and cost

A new study explores the acceptability and usage of COVID-19 vaccines among the student community.

4 Nov 2021

Anti-inflammatory diets in COVID-19

A recent review of research published in the journal Diseases has shown that anti-inflammatory diets can be useful in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or reducing the severity of coronavirus disease 2019 (COVID-19).

3 Nov 2021

Clinical Trial News and Research

Retinoid therapy improves vision in mice with Usher syndrome

Proton therapy used for the first time in Switzerland to treat lung cancer

Repeated listening to favorite music induces beneficial brain plasticity in Alzheimer’s patients

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Exercise can alleviate symptoms of anxiety, study shows

COVID-19 drug candidate with wide-ranging antiviral activity

Novel study aims to develop personalized treatment for triple-negative breast cancer

Clinical trial compares Amulet with Watchman FLX device for percutaneous left atrial appendage closure

International Alzheimer’s trial to evaluate a combination of drugs targeting two brain proteins

Study points to a new, effective treatment option for patients with mesothelioma

Diabetes medication reduces the rate of kidney function decline in CKD patients

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

New type of COVID vaccine potentially easier to produce and does not need refrigeration

Researchers use suction method to deliver SARS-CoV-2 DNA vaccine in lab tests

Ibrutinib plus standard chemotherapy effective in younger patients with diffuse large B-cell lymphoma

MHRA approves first oral antiviral for the treatment of COVID-19

Clear communication needed with college students regarding COVID-19 vaccine procedures and cost

Anti-inflammatory diets in COVID-19

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