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Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Brain organoids provide new insights into HSV-1 encephalitis

The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists with the Rajewsky and Landthaler labs and the Organoid Platform at the Max Delbrück Center in Nature Microbiology.

22 Jun 2023

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Leishmaniasis is a tropical disease caused by parasites known as Leishmania, which are transmitted to humans and animals through the bites of more than 90 species of sand flies.

22 Jun 2023

Neurons involved in creating negative emotional states and chronic stress identified

Researchers at Karolinska Institutet in Sweden have identified a group of nerve cells in the mouse brain that are involved in creating negative emotional states and chronic stress. The

22 Jun 2023

The benefits and harms of screening and treatment for anxiety and the accuracy of instruments to detect anxiety among primary care patients

Researchers from the United States (U.S.) reviewed the risks and benefits of anxiety screening and treatment.

22 Jun 2023

Parental loss at a young age affects a person’s immune system later in life

When a person loses a parent or a caregiver at a young age, their immune system suffers later in life, according to University of Michigan research.

21 Jun 2023

Repurposing cancer drugs for malaria treatment

With malaria becoming increasingly drug-resistant, a team of UCF researchers is looking to use cancer drugs to accelerate the discovery of new life-saving therapies for the disease.

21 Jun 2023

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

Live parental infant-directed singing has positive impacts on infants' emotional regulation, validation of the parent's role, and affect attunement, as identified in a systematic review of 21 studies. Benefits are observed in typically developing infants born at full term.

21 Jun 2023

Testosterone function changes within individuals across adolescence and adulthood, study suggests

Higher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion control, but the opposite effect occurs during adulthood.

21 Jun 2023

Ketone supplements used by some athletes may worsen performance

Kinesiologists at McMaster University have found ketone supplements, used by some athletes hoping to cross the finish line faster, may in fact worsen performance.

21 Jun 2023

Study finds stark racial and ethnic disparities in alcohol-induced mortality among US adults during the pandemic

Alcohol-related deaths rose disproportionately quickly in the US among Black, Hispanic, Asian and American-Indian/Alaska Native populations at the start of the COVID-19 pandemic, new research shows.

21 Jun 2023

Study investigates the interplay between acute stress and placebo effects in nausea

Researchers investigated the interplay between acute stress and placebo effects on nausea.

21 Jun 2023

The impact of dietary carotenoids and vitamin C intake on the association between fruits and vegetable diet and preeclampsia

Researchers assessed the impact of dietary carotenoids and vitamin C intake on the association between fruits and vegetable diet and preeclampsia.

21 Jun 2023

Stress News and Research

Study reveals contrasting effects of sucralose on insulin and glucose control

Brain organoids provide new insights into HSV-1 encephalitis

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Neurons involved in creating negative emotional states and chronic stress identified

The benefits and harms of screening and treatment for anxiety and the accuracy of instruments to detect anxiety among primary care patients

Parental loss at a young age affects a person’s immune system later in life

Repurposing cancer drugs for malaria treatment

Lullabies strike a chord: Singing to babies strengthens Bonds and boosts development

Testosterone function changes within individuals across adolescence and adulthood, study suggests

Ketone supplements used by some athletes may worsen performance

Study finds stark racial and ethnic disparities in alcohol-induced mortality among US adults during the pandemic

Study investigates the interplay between acute stress and placebo effects in nausea

The impact of dietary carotenoids and vitamin C intake on the association between fruits and vegetable diet and preeclampsia

Building resilient brains: strategies for promoting brain health in older adults

Elevated heart rate can induce a stroke in patients with highly blocked carotid arteries

Intranasal delivery of CRISPR/Cas9 therapeutics may help treat chronic anxiety

Older people do not know enough about the risks associated with drinking alcohol, research shows

Study suggests that the overall physical health of adolescents was negatively impacted by COVID-19 mitigation efforts

CBD and THC: promising remedies for aluminum-related neurological damage

Urban jungle: How city living may impact mental health

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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