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Leptin could combat type 2 diabetes

University of Florida researchers have discovered the appetite-controlling hormone leptin could also combat type 2 diabetes, a disease that has become a growing problem in the United States as more Americans pack on extra pounds.

21 Sep 2006

Combating generics: pharmaceutical brand defense for 2007

Court cases regarding patent infringement effectively slow generics in coming to market, however US lawmakers and FDA continue to make it easier for generic drugs to gain approval (Cutting Edge Information).

21 Sep 2006

Unpleasant memories from intensive care

"Being cared for in an intensive care unit (ICU) can never be an especially positive experience. But at any rate it should not mean that the care improves the patient's physical condition only to leave him or her with severe mental problems!"

20 Sep 2006

Computer model reveals a central "road" in the human stomach

A computer model or "virtual stomach" revealed a central "road" in the human stomach, dubbed the Magenstrasse, that could explain why pharmaceuticals sometimes have a large variability in drug activation times, according to a team creating computer simulations of stomach contractions.

20 Sep 2006

Risks of gastrointestinal ulcers linked to aspirin use might outweigh its benefits for the heart in certain patients

Doctors should consider whether patients are at high risk of stomach ulcers before prescribing aspirin treatment.

20 Sep 2006

World Health Organization launches International Drug Purchase Facility

The World Health Organization (WHO) has officially launched UNITAID, the International Drug Purchase Facility being established by Brazil, France, Chile, Norway and the United Kingdom.

20 Sep 2006

Regenerative Medicine wins award for best new journal

The journal Regenerative Medicine has been recognized by The Association of Learned and Professional Society Publishers as joint winner of the 2006 ALPSP/Charlesworth Award for Best New Journal. This prestigious international award is presented annually to the best new journal across a wide range of disciplines.

20 Sep 2006

GSK seeks regulatory approval in U.S., Europe for Tykerb

GlaxoSmithKline on Monday said it has submitted its experimental breast cancer drug Tykerb, which is taken orally, for FDA approval and plans to file for approval in Europe in the fourth quarter of this year, Reuters reports.

20 Sep 2006

Use of unapproved drugs in the U.S.

USA Today on Monday looked at the use of unapproved drugs in the U.S., including some that are used to treat menopause symptoms (Rubin, USA Today, 9/18).

20 Sep 2006

Many Australian physicians not applying for permission to import Mifepristone

Many Australian physicians are not applying for permission to supply mifepristone to women in the country and instead are prescribing women a combination of methotrexate -- a drug licensed to treat cancer patients -- and misoprostol to induce a medical abortion.

20 Sep 2006

USAID issues $15M grant to Ugandan religious coalition

USAID through the President's Emergency Plan for AIDS Relief issued a $15 million three-year grant to the Inter-Religious Council of Uganda -- a coalition of five religious groups that promote faith-based strategies to fight the HIV/AIDS epidemic, AFP/Today Online reports.

20 Sep 2006

Five countries to tax airline travel to raise money for HIV/AIDS

Brazil, Chile, France, Norway and the United Kingdom on Tuesday at the 61st session of the U.N. General Assembly are expected to announce a plan to impose an airline ticket tax to fund an international drug purchase facility and HIV/AIDS, tuberculosis and malaria treatment and prevention programs, a French official said Monday, the New York Times reports.

20 Sep 2006

160 HIV-positive delegates at XVI International AIDS conference make refugee claims in Canada

About 160 HIV-positive people who entered Canada from other countries to attend the XVI International AIDS Conference in Toronto last month have made refugee claims to stay in the country, Toronto's Globe and Mail reports.

20 Sep 2006

Thousands of prescription drug products sold in the U.S. not approved by FDA

Drugs that have not been approved by FDA make up nearly 2% of prescription drugs on the market, and some of them "might not only be ineffective but also might actually be harmful," USA Today reports.

20 Sep 2006

Insurance companies promote use of generic drugs in effort to cut costs

The Chicago Tribune on Sunday examined how some private insurers, in an attempt to reduce health care costs by encouraging the use of generic drugs, "are showering customers with free generic drug samples, waiving copayments and marketing directly to consumers in doctors' offices."

20 Sep 2006

Nicotinamide may help people with multiple sclerosis

Researchers have found a possible way to protect people with multiple sclerosis (MS) from severe long-term disability: increase nervous-system levels of a vital compound, called nicotinamide adenine dinucleotide (NAD), by giving its chemical precursor - nicotinamide, a form of vitamin B3.

19 Sep 2006

Cisplatin nanoliposomes for cancer therapy

Cisplatin is one of the most powerful and effective drugs for treating a wide variety of cancers, but many tumors develop resistance to this drug, ultimately limiting its benefits for cancer patients.

19 Sep 2006

FDA approves Noxafil (posaconazole) to prevent invasive fungal infections

The U.S. Food and Drug Administration has approved Noxafil (posaconazole) to prevent fungal infections caused by certain molds and yeast-like fungus called Aspergillus and Candida.

19 Sep 2006

Researchers create roadmap to integrin activation

Calling it an important technical advance in the study of the complex receptors and pathways of the body's cellular system, researchers at the University of California, San Diego (UCSD) School of Medicine have reconstructed the signaling pathways that impact activation of a receptor that is critical to the control of bleeding and to the thrombosis that occurs in heart attacks and strokes.

18 Sep 2006

Sen. DeMint pledges to hold Von Eschenbach's FDA Commissioner nomination unless steps taken to take Mifeprex off market

Sen. Jim DeMint (R-S.C.) plans to place a hold on President Bush's nomination of acting FDA Commissioner Andrew von Eschenbach to permanently head the agency unless "immediate steps" are taken to remove Danco Laboratories' medical abortion drug Mifeprex from the market, DeMint press secretary Wesley Denton said recently, the New York Times reports.

18 Sep 2006