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Drug pactimibe does not appear to reduce progression of atherosclerosis

Compared to placebo, the drug pactimibe did not effect certain measures of atherosclerosis for patients with familial hypercholesterolemia (high cholesterol levels), but these patients did have an increased incidence of cardiovascular events such as heart attack and stroke, according to a study in the March 18 issue of JAMA.

17 Mar 2009

Medical costs for one premature baby could cover a dozen healthy births

The medical costs that businesses pay to care for one premature baby for a year could cover the costs for nearly a dozen healthy, full-term infants, according to new statistics from the March of Dimes.

17 Mar 2009

Lung cancer: Molecular scissors determine therapy effectiveness

In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells.

17 Mar 2009

Hearing could hold key to unlocking schizophrenia mystery

Measuring brain waves in response to hearing a variety of tones appears to be a useful way to begin understanding the underlying genetic abnormalities associated with schizophrenia, says a study headed by researchers at Harvard-affiliated McLean Hospital.

17 Mar 2009

Drug being used to improve cognition affects dopamine, suggesting potential for abuse

Preliminary research in healthy men suggests that the narcolepsy drug modafinil, increasingly being used to enhance cognitive abilities, affects the activity of dopamine in the brain in a way that may create the potential for abuse and dependence, according to a study in the March 18 issue of JAMA.

17 Mar 2009

1 in 4 Americans lacks timely access to optimal care during time-sensitive medical emergencies

Although most Americans live close to some type of emergency room, as many as one in four Americans are more than an hour away from the type of hospital that's most prepared to save their life during a time-sensitive medical emergency, according to a new University of Pennsylvania School of Medicine study published in the journal Annals of Emergency Medicine.

17 Mar 2009

A living representation of the brain created by scientists

Researchers in the School of Life & Health Sciences at Aston University in Birmingham, UK are developing a novel new way to model how the human brain works by creating a living representation of the brain.

17 Mar 2009

Discovery of new mechanism for the processing of endocannabinoids

New research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, has identified a new mechanism for the processing of endocannabinoids, natural brain compounds similar to THC, the active ingredient in marijuana.

17 Mar 2009

Suberoylanilide hydroxamic acid 'turns on' latent HIV

HAART (highly active anti-retroviral therapy) has emerged as an extremely effective HIV treatment that keeps virus levels almost undetectable; however, HAART can never truly eradicate the virus as some HIV always remains dormant in cells.

16 Mar 2009

Aspirin decreases first heart attacks in men and first strokes in women

Patients and clinicians should consider risk factors -- including age, gender, diabetes, blood pressure, cholesterol levels, smoking and risk of gastrointestinal bleeding -- before deciding whether to use aspirin to prevent heart attacks or strokes, according to new recommendations from the U.S. Preventive Services Task Force.

16 Mar 2009

President Obama's insurance for children - shouldn't we at least talk about it?"

Democrats are moving quickly to socialize American health care with the SCHIP expansion. Michael Tanner of the CATO Institute whined, "Shouldn't we at least talk about it?"

16 Mar 2009

Shire withdraws European application for Daytrana (Methylphenidate Transdermal System)

Shire plc has announced that it has decided to withdraw the European Marketing Authorization Application (MAA) for Daytrana (methylphenidate transdermal system) for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).

16 Mar 2009

Risks of using aspirin to prevent heart attack or stroke differ by gender and age

Patients and clinicians should consider risk factors-- including age, gender, diabetes, blood pressure, cholesterol levels, smoking and risk of gastrointestinal bleeding-- before deciding whether to use aspirin to prevent heart attacks or strokes, according to new recommendations from the U.S. Preventive Services Task Force.

16 Mar 2009

New target for heart failure therapy identified

A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers.

16 Mar 2009

Tiny probes help track down and attack cancer cells

A researcher has developed probes that can help pinpoint the location of tumors and might one day be able to directly attack cancer cells.

16 Mar 2009

Discovery of master switch that might prevent cancer cells from metastasizing

Researchers at the University of Pennsylvania School of Medicine have identified a master switch that might prevent cancer cells from metastasizing from a primary tumor to other organs.

16 Mar 2009

Trial of new combination treatment targeting hormone receptor-positive locally advanced breast cancer

Researchers at The Cancer Institute of New Jersey (CINJ) have opened a clinical trial, which aims to evaluate a new treatment for breast cancer in combination with one that is already approved for other types of cancers.

16 Mar 2009

First treatment for muscular dystrophy a step closer

Genetic researchers at Children's National Medical Center and the National Center of Neurology and Psychiatry in Tokyo published the results of the first successful application of "multiple exon-skipping" to curb the devastating effects of Duchenne muscular dystrophy in an animal larger than a mouse.

16 Mar 2009

Updated guidelines for ovarian cancer

Improvements in screening and early detection remains the key for women with ovarian cancer according to Robert J. Morgan, MD, of City of Hope Comprehensive Cancer Center and chair of the NCCN Guidelines Panel for Ovarian Cancer.

16 Mar 2009

Drugs throw spanner into the molecular works of enzymes

Drugs that work by blocking the function of a protein from the outside also disrupt the protein's internal workings, according to new research from the University of North Carolina at Chapel Hill.

16 Mar 2009