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PTPN2 gene protects the gut from harmful bacteria driving inflammatory bowel disease

Two recent studies from the University of California, Riverside, published in the same issue of Gut Microbes highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD).

24 Jan 2026

Short-term oatmeal diet improves cholesterol and metabolic health markers

A short-term oat-based diet appears to be surprisingly effective at reducing the cholesterol level. This is indicated by a trial by the University of Bonn, which has now been published in the journal Nature Communications.

23 Jan 2026

Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality

Bacterial infections (BIs) are common and severe complications in patients with liver cirrhosis, but global data are limited. Here, we aimed to evaluate the global prevalence, temporal changes, and associated mortality risk of BIs in liver cirrhosis.

23 Jan 2026

Scientists discover a non-classical platelet mechanism linked to severe infections

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor integrin αIIbβ3. This leads to the formation of a stable platelet plug that seals the wound and stops bleeding. When this process becomes dysregulated, however, it can result in vessel-occluding clots - so-called thromboses - which may cause myocardial infarction or stroke.

23 Jan 2026

Study traces deep origins of syphilis to prehistoric Americas

A newly sequenced genome of the bacterium that causes syphilis, Treponema pallidum, highlights the deep antiquity of treponemal diseases in the Americas.

22 Jan 2026

Targeted uterine mRNA treatment boosts fertility outcomes in mice

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine - which designs nanotechnology-based platforms for clinical translation across specialties - developed a strategy for delivering therapeutic messenger RNA (mRNA) to the inner lining of the uterus (endometrium) in mice via modified lipid nanoparticles (LNPs), which are small capsules made of fatty molecules.

22 Jan 2026

Age-related changes in the gut microbiota impair intestinal stem cell function

A new study led by Hartmut Geiger at the University of Ulm, Germany, and Yi Zheng and Kodandaramireddy Nalapareddy, Cincinnati Children's Hospital Medical Center (CCHMC), USA reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

22 Jan 2026

Bacteria behind Nagashima-type palmoplantar keratosis foot odor identified

The distinct foot odor that comes with the skin disorder Nagashima-type palmoplantar keratosis (NPPK) is caused by the overgrowth of a specific bacterial strain.

22 Jan 2026

High-dose inhaled nitric oxide could fight multidrug-resistant infections

Overuse of antibiotics has accelerated the development of bacterial resistance to conventional drugs, a global health crisis projected to result in more than 10 million deaths annually by 2050.

21 Jan 2026

Analyzing bacterial enzymes in pikromycin synthesis

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin infections.

21 Jan 2026

Ancient ice and modern pollution combine to spread antibiotic resistance as glaciers melt

Glaciers harbor both ancient and human-derived antibiotic resistance genes, preserved in ice and increasingly mobilized by climate-driven melt. This global review proposes a glacier-to-downstream “continuum” to understand how resistance genes may move through connected freshwater ecosystems.

18 Jan 2026

Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

16 Jan 2026

Gut microbiota analysis offers insights into how ultra processed foods affect health

To gain more knowledge about how ultra-processed food affects us, we need new research methods, claim researchers. Now they are looking to better understand our intestinal flora.

16 Jan 2026

Study reveals how antibiotic resistant bacteria delay chronic wound healing

An international team of scientists, led by Nanyang Technological University, Singapore (NTU Singapore), has discovered a new way that could speed up the healing of chronic wounds infected by antibiotic-resistant bacteria.

16 Jan 2026

PRoRota-project aims to fight diarrhea in children using probiotics, hygiene, and models

The PRoRota-project will use probiotics, improved education in hygiene and advanced mathematical models to prevent children from dying of diarrhea in low and middle-income countries.

16 Jan 2026

Water dispensers may contain more bacteria than tap water

A review reveals that water dispensers may harbor microbial contamination, challenging their safety compared to tap water and highlighting maintenance needs.

16 Jan 2026

Scientists reveal how cholera bacteria activate toxin genes in the human gut

Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year.

14 Jan 2026

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.

14 Jan 2026

Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation

Pregnant individuals with inflammatory bowel disease (IBD) have higher levels of pro-inflammatory immune molecules, known as cytokines, in their vaginal mucosa than their healthy counterparts, according to a new study published January 14, 2026 in the open-access journal PLOS One by Ana Maldonado-Contreras of University of Massachusetts Chan Medical School, U.S., and colleagues.

14 Jan 2026

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

14 Jan 2026

Bacterial News and Research

PTPN2 gene protects the gut from harmful bacteria driving inflammatory bowel disease

Short-term oatmeal diet improves cholesterol and metabolic health markers

Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality

Scientists discover a non-classical platelet mechanism linked to severe infections

Study traces deep origins of syphilis to prehistoric Americas

Targeted uterine mRNA treatment boosts fertility outcomes in mice

Age-related changes in the gut microbiota impair intestinal stem cell function

Bacteria behind Nagashima-type palmoplantar keratosis foot odor identified

High-dose inhaled nitric oxide could fight multidrug-resistant infections

Analyzing bacterial enzymes in pikromycin synthesis

Ancient ice and modern pollution combine to spread antibiotic resistance as glaciers melt

Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts

Gut microbiota analysis offers insights into how ultra processed foods affect health

Study reveals how antibiotic resistant bacteria delay chronic wound healing

PRoRota-project aims to fight diarrhea in children using probiotics, hygiene, and models

Water dispensers may contain more bacteria than tap water

Scientists reveal how cholera bacteria activate toxin genes in the human gut

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

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