Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

New model identifies cancer patients at high risk for ER visits during clinical trials

Investigators from the SWOG Cancer Research Network have developed and validated a risk prediction model for identifying which patients with advanced cancer who are enrolled to clinical trials are at highest risk for unplanned emergency room (ER) visits and hospital stays.

23 Sep 2024

Yoyo dieting alters gut health, driving weight regain and inflammation

Researchers from Deakin University reveal how yoyo dieting disrupts gut health, leading to weight regain and obesity-related complications. The study highlights the roles of gut microbiota, hormones, and inflammation in the weight cycling process.

23 Sep 2024

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

Scientists from the University of Copenhagen have detected lipid biomarkers in children and teenagers with obesity that indicate an increased risk of developing type 2 diabetes, liver and heart disease as adults.

20 Sep 2024

Study reveals sex differences in T-cell responses among lung cancer patients

Researchers at Saint Louis University School of Medicine investigated differences in T-cell responses between male and female patients with lung cancer that may help direct future treatments.

20 Sep 2024

New blood test identifies obesity-related health risks in children

A new type of blood test using lipids could make it easier to identify children at risk of complications around obesity including type two diabetes, liver and heart disease, say scientists.

20 Sep 2024

The importance of mitochondrial function in health and disease

The World Mitochondria Society (WMS) is preparing for its annual Targeting Mitochondria 2024 conference, which will focus on innovative strategies to "charge" cells by supplying them with extra mitochondria to enhance cellular function and combat diseases.

18 Sep 2024

Loneliness may not be a direct cause of disease

A study reveals loneliness correlates with 13 illness categories, highlighting its role as a potential proxy marker rather than a direct risk factor.

17 Sep 2024

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM) at the University of Barcelona, reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic dysfunction-associated steatotic liver disease).

17 Sep 2024

Review highlights mitochondrial dysfunction in cholestatic liver injury

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats.

16 Sep 2024

Higher soft drink consumption linked to increased risk of liver disease

Study found that higher soft drink consumption is associated with an increased risk of nonalcoholic fatty liver disease, especially in males, within a cohort of Mexican adults.

16 Sep 2024

NIH funds new research to combat emerging viruses

Albert Einstein College of Medicine has received a five-year, $14 million per year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to participate in a broad national effort to develop "plug-and-play" vaccines and antibody-based therapies against a wide range of emerging viruses. The grant is part of NIAID's new Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network, which was announced earlier today.

14 Sep 2024

New IndiPHARM initiative aims to revolutionize personalized medication management

A Columbia University-led multicenter research effort called IndiPHARM: individual metabolome and exposome assessment for pharmaceutical optimization will develop a platform and monitoring system to prevent unwanted interactions between medications and other environmental, genetic, and lifestyle factors, in order to optimize therapeutic efficacy.

12 Sep 2024

Brazilian research uncovers how liver nerves regulate glucose production under stress

A study led by Brazilian researchers has produced a detailed description of the morphology of the nerves in the liver and how they control production of glucose when the organism is under stress.

11 Sep 2024

A promising new therapeutic target for MASLD identified

Using a novel stem cell platform, a team of the Medical University of South Carolina researchers has identified a pathway that could be targeted by drugs to reduce fat accumulation in patients with a common form of fatty liver disease known as metabolic dysfunction-associated steatotic liver disease, or MASLD.

11 Sep 2024

Long-term exercise leads to healthier fat storage in obese individuals

People with obesity who are long-time exercisers have healthier belly fat tissue and can store fat there more effectively than nonexercisers with obesity, according to a new study from a team of researchers at the University of Michigan.

10 Sep 2024

Raw white garlic shows promise in boosting heart health and reducing disease risks

Review highlights the potential health benefits of raw white garlic consumption, particularly in improving cardiometabolic biomarkers and reducing chronic disease risks.

8 Sep 2024

Long-term air pollution exposure and poor lifestyle choices increase risk of non-alcoholic fatty liver disease

Long-term exposure to air pollution and poor lifestyle choices are key contributors to non-alcoholic fatty liver disease (NAFLD), affecting global liver health.

3 Sep 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

23 Aug 2024

Probiotic offers protection against intestinal damage

There is a critical unmet need to help tighten and maintain a healthy intestinal barrier and treat a leaky gut. Researchers have now found that a unique strain of probiotic bacteria, Bifidobacterium bifidum BB1, enhances intestinal barrier function and protects against penetration of bacteria and various harmful agents in the intestine. The findings, detailed in an article in The American Journal of Pathology, published by Elsevier, can help advance the development of novel, targeted, naturally occurring probiotic therapy for patients with inflammatory bowel disease (IBD) and other inflammatory diseases, such as fatty liver disease or alcoholic liver disease, that are associated with a leaky or disordered intestinal barrier.

23 Aug 2024

Liver Disease News and Research

Further Reading

New model identifies cancer patients at high risk for ER visits during clinical trials

Yoyo dieting alters gut health, driving weight regain and inflammation

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

Study reveals sex differences in T-cell responses among lung cancer patients

New blood test identifies obesity-related health risks in children

The importance of mitochondrial function in health and disease

Loneliness may not be a direct cause of disease

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

Review highlights mitochondrial dysfunction in cholestatic liver injury

Higher soft drink consumption linked to increased risk of liver disease

NIH funds new research to combat emerging viruses

New IndiPHARM initiative aims to revolutionize personalized medication management

Brazilian research uncovers how liver nerves regulate glucose production under stress

A promising new therapeutic target for MASLD identified

Long-term exercise leads to healthier fat storage in obese individuals

Raw white garlic shows promise in boosting heart health and reducing disease risks

Long-term air pollution exposure and poor lifestyle choices increase risk of non-alcoholic fatty liver disease

Study reveals key role of A20 protein in controlling inflammation in liver disease

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

Probiotic offers protection against intestinal damage

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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