Nucleic Acid News and Research

RSS

Saliva samples show better sensitivity for early stages of COVID-19 detection

Study explores the advantages of saliva compared to MTS and recommends the use of saliva for large-scale screening of COVID-19, especially in pre-symptomatic patients.

6 Dec 2021

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

In this paper, a group of researchers from Harvard Medical School, McGill University, and Tianjin University describes an on-chip diagnostic technology for the direct detection of SARS-CoV-2 N protein in nasal samples that combines the advantages of hydrodynamic microfluidic filtration and sandwich immunoassay.

5 Dec 2021

Study finds third dose of BNT162b2 or mRNA-1273 is moderately effective against post-vaccination COVID-19 infection

The current study used VHA electronic health records (EHR) to estimate the effectiveness of the booster dose in the USA against post-vaccination COVID-19.

3 Dec 2021

Automate your sample pooling with INTEGRA’s efficient pipetting solutions

INTEGRA’s automated pipetting solutions are helping scientists meet the challenge of efficiently pooling potentially infectious samples prior to testing.

From INTEGRA Biosciences 3 Dec 2021

Special collection of articles highlights China's response to covid-19

Today, The BMJ is launching a special collection of articles on China's response to covid-19 - what it was, how it worked, why traditional public health measures played such a vital role, and how other countries can learn from this experience to protect their populations, in particular in future pandemics.

2 Dec 2021

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Researchers employ a structure-guided approach for the development of a series of ACE2-Fc variants using human IgG1 or IgG3 backbone.

1 Dec 2021

Plant-derived virus-like particle vaccines against SARS-CoV-2

In a review published in Biotechnology Letters, the authors discuss plant-derived VLP-based vaccines.

1 Dec 2021

Study shows long-term safety and biologic activity of golodirsen in DMD patients

This first-in-human study of golodirsen showed its long-term safety and biologic activity in patients with Duchenne Muscular Dystrophy (DMD). The approved exon-skipping therapy is designed to enable the production of functional dystrophin proteins, as described in the peer-reviewed journal Nucleic Acid Therapeutics.

1 Dec 2021

Study shows that nucleic acid amplification tests more accurate in detecting SARS-CoV-2 than rapid antigen

Researchers use reference preparations from pooled swab samples to compare the analytical sensitivity of different SARS-CoV-2 assays

30 Nov 2021

How COVID-19 protection conferred by infection is modified by vaccination

The authors of a recent study investigated how vaccination, administered before or after the first COVID-19 infection, modifies the protective effect of the previous infection against reinfection.

29 Nov 2021

Immunity found 6 months after SARS-CoV-2 infection in children

A new study suggests that infection-induced antibodies persist, providing protection for at least six months.

29 Nov 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

A new study published in the journal Diagnostics was based on the hypothesis that detecting urinary SARS-CoV-2 nucleic acid––which may result in renal and cardiovascular endothelial destruction to facilitate viral access to the kidney parenchyma—may be used as a specific biomarker to indicate the severity of COVID-19.

16 Nov 2021