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COVID-19 severity is linked to changes in mitochondrial DNA methylation

This study examined mitochondrial and nuclear-encoded mitochondrial DNA methylation in Indian patients with severe COVID-19 and found region-specific differential methylation linked to disease severity. Pathway analyses and protein assays implicated disrupted mitochondrial metabolism and dynamics, suggesting a role for mitochondrial epigenetic regulation in COVID-19 pathophysiology.

20 Jan 2026

New genetic insights reveal vitamin B1's role in gut health and motility

Bowel habits aren't exactly dinner-table talk. But they reflect how quickly the gut moves things along, and when that goes wrong people can experience constipation, diarrhoea, or irritable bowel syndrome (IBS).

20 Jan 2026

Genomic screening uncovers hidden cancer and heart disease risk in young adults

A nationwide Australian pilot screened more than 10,000 adults aged 18–40 years for high-risk genetic variants linked to hereditary cancer and familial hypercholesterolaemia, identifying clinically actionable findings in about 2% of participants.

19 Jan 2026

PFAS exposure increases gestational diabetes risk

A review of 130 studies links PFAS exposure to gestational diabetes, highlighting the need for further research on diabetes outcomes and environmental factors.

19 Jan 2026

Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome

The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to target precancerous and cancerous cells in individuals with Lynch Syndrome (LS), according to a study from researchers at The University of Texas MD Anderson Cancer Center.

16 Jan 2026

Monash experts urge funding for national genomic screening to prevent disease

Leading genomic health experts from Monash University are calling for urgent government funding to progress the development of a national preventive genomic testing program that would save thousands of Australians from conditions like cancer and heart disease.

16 Jan 2026

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.

14 Jan 2026

Research shows racial-ethnic differences in the risk of pregnancy-related high blood pressure

The risk of pregnancy-related high blood pressure varied markedly among subgroups of Asian American, Native Hawaiian and Pacific Islander people, highlighting the need for tailored prevention and treatment, according to research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

14 Jan 2026

Light daily movement linked to longer life in cardiometabolic disease

Researchers determine the impact of light physical activity on mortality in people with cardiovascular-kidney-metabolic syndrome.

14 Jan 2026

New research identifies faulty TRPM3 ion channel in ME/CFS immune cells

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), providing long-awaited validation for hundreds of thousands of Australians living with the debilitating illness.

13 Jan 2026

Why adherence determines weight loss success with semaglutide

Researchers examine how the effectiveness of weight-loss medications may depend on the patient adherence.

12 Jan 2026

Long COVID symptom clusters that could reshape patient care

A systematic review of Long COVID identifies symptom clusters, highlighting fatigue and proposing a management framework for personalized treatment strategies.

12 Jan 2026

How pandemic viruses spread across U.S. cities before anyone notices

Researchers reconstruct the spatial spread of pandemic respiratory viruses across metropolitan areas throughout the United States

12 Jan 2026

AI automates sister chromatid exchange counting, improving diagnosis of Bloom syndrome

Researchers from Tokyo Metropolitan University have developed a suite of algorithms to automate the counting of sister chromatid exchanges (SCE) in chromosomes under the microscope.

10 Jan 2026

George Mason trial: New pill aims to sustain weight loss after GLP-1s

GLP-1 medications like Ozempic and Wegovy have transformed obesity treatment, but maintaining weight loss after the medications stop remains a challenge.

9 Jan 2026

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors.

8 Jan 2026

Specific gut bacteria found to drive alcohol production in patients with auto-brewery syndrome

Researchers at University of California San Diego, Mass General Brigham, and their colleagues have identified specific gut bacteria and metabolic pathways that drive alcohol production in patients with auto-brewery syndrome (ABS).

8 Jan 2026

Why promising microbiome therapies rarely work in patients

Addressing the microbiome's translational gap involves understanding biological complexity and developing function-driven, patient-specific interventions.

8 Jan 2026

Light daily movement linked to lower mortality risk in people with CKM syndrome

Light intensity activities, like walking or household chores, were linked to a lower risk of death for people with cardiovascular-kidney-metabolic (CKM) syndrome, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

7 Jan 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026