Clinical Trial News and Research

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Immunocompromised patients using rituximab could benefit from third COVID-19 booster vaccine

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows immunocompromised patients using rituximab (a drug used to treat diseases like rheumatoid arthritis) were able to produce antibodies against COVID-19 (seroconvert) after receiving a third COVID-19 vaccine dose, even if there was no development of the antibody after the first two doses of the vaccine.

2 Nov 2021

Study shows cognitive effects of ready-to-use enhanced therapeutic food in malnourished children

A nutritional supplement popular in the U.S. and added to some types of yogurt, milk and infant formula can significantly improve cognition in severely malnourished children, according to a study led by researchers at Washington University School of Medicine in St. Louis.

2 Nov 2021

Immune checkpoint protein may be a promising new target for prostate cancer immunotherapy

The immune checkpoint protein B7-H3 may be a promising new target for immunotherapy in treatment-resistant prostate cancers, according to two new studies led by researchers at the Johns Hopkins Kimmel Cancer Center.

2 Nov 2021

Understanding the current medical landscape of prostate cancer

In this interview, News-Medical talks to Dr. Simon Chowdhury and Laetitia Guilloux about the current state of prostate cancer, it's prevalence, treatment options and its future.

From Janssen Pharmaceuticals 2 Nov 2021

What do we really know about vaccine effectiveness?

The politicization of covid vaccines — and, well, just about everything else having to do with the pandemic — has led to confusion, if not utter fatigue.

2 Nov 2021

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the COVID-19 vaccine was not associated with severe disease flares in patients with rheumatic diseases.

1 Nov 2021

Platelet inhibitors may be linked with reduction in digital ulcers in people with systemic sclerosis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of platelet inhibitors could be associated with a reduction in the occurrence of digital ulcers, painful sores on the extremities that can progress to gangrene, in people with systemic sclerosis.

1 Nov 2021

Researchers develop a new test to more easily diagnose medulloblastoma

Researchers at the University of British Columbia and BC Cancer, in partnership with BC Children's Hospital Research Institute, have developed a new test to more easily diagnose medulloblastoma, the most common malignant childhood brain tumor.

1 Nov 2021

Largest real-world study evaluates the effectiveness of third "booster" dose of COVID-19 vaccine

The Clalit Research Institute, in collaboration with researchers from Harvard University, analyzed one of the world's largest integrated health record databases to examine the effectiveness of the third dose of the Pfizer/BioNTech BNT162B2 vaccine against the Delta variant of SARS-CoV-2.

30 Oct 2021

Harnessing the genetics of hookworms to develop next generation of PPE for combat troops

Researchers at Washington University School of Medicine in St. Louis have received a grant to develop the next generation of personal protective equipment (PPE) for combat troops.

30 Oct 2021

New EcoTyper tool can help identify cancer subtypes

Researchers at the Stanford Institute for Stem Cell Biology and Regenerative Medicine have devised a tool to examine how cells behave and interact in various environments of the body.

30 Oct 2021

Two new studies show how to enhance effectiveness of cancer immunotherapy

Two new studies revealed that anti-PD-1 immunotherapy given before surgery was safe and effective for patients with oral-cavity squamous cell carcinoma (OCSCC) and identified potential molecular biomarkers in the blood and tumors of patients that would show how likely it is that someone would respond to immunotherapy.

30 Oct 2021

Therapeutic heparin for preventing COVID-19 deaths is four times higher than the prophylactic dose

The anti-coagulant heparin reduces the likelihood of death from COVID-19 by 78% when administered in therapeutic doses to patients with signs of respiratory failure on admission to hospital, according to a study reported on October 14 in the British Medical Journal.

30 Oct 2021

Countermarketing messages convinces many parents to avoid buying sugary drinks for children

Public health messages such as in the image (associated with this release) - designed to reduce parents' purchases of sugar-sweetened beverages marketed as fruit drinks or children - convinced a significant percentage of parents to avoid those drinks, according to a study by researchers at the University of Washington and the University of Pennsylvania.

30 Oct 2021

Forgotten antibiotic may be useful in treating severe febrile urinary tract infections

A forgotten antibiotic, temocillin, led to lower selection of resistant bacteria than the standard treatment for febrile urinary tract infection, in a study published in The Lancet Infectious Diseases.

29 Oct 2021

Magnus Medical receives FDA's Breakthrough Device Designation for rapid-acting technology to treat major depression

Magnus Medical, Inc., a medical device company, today announced that the U.S. Food & Drug Administration (FDA) has granted the company Breakthrough Device Designation for its individualized, rapid-acting, non-invasive neurostimulation technology designed to treat major depressive disorder (MDD) in people who have not improved sufficiently from antidepressant medication or other treatments.

29 Oct 2021

NIH study identifies distinct mechanisms of long-term HIV control in two people after treatment disruption

Research led by scientists at the National Institutes of Health has identified two distinct ways that people with HIV can control the virus for an extended period after stopping antiretroviral therapy (ART) under medical supervision.

29 Oct 2021

Study finds early fluvoxamine treatment among COVID-19 patients reduces hospitalization

A team of researchers conducted a randomized, placebo-controlled, adaptive platform trial to evaluate the efficacy of fluvoxamine to prevent COVID-19 progression and hospitalization.

29 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

Study offers hope for a new therapeutic option for patients with severe asthma

A new monoclonal antibody therapy shows promise in offering an alternative treatment for patients suffering from moderate-to-severe asthma. Research led by Michael E. Wechsler, MD, MMSc, director of the National Jewish Health Cohen Family Asthma Institute, found that itepekimab was safe and effective in a phase 2 trial published online today in the New England Journal of Medicine.

28 Oct 2021

Clinical Trial News and Research

Immunocompromised patients using rituximab could benefit from third COVID-19 booster vaccine

Study shows cognitive effects of ready-to-use enhanced therapeutic food in malnourished children

Immune checkpoint protein may be a promising new target for prostate cancer immunotherapy

Understanding the current medical landscape of prostate cancer

What do we really know about vaccine effectiveness?

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

Platelet inhibitors may be linked with reduction in digital ulcers in people with systemic sclerosis

Researchers develop a new test to more easily diagnose medulloblastoma

Largest real-world study evaluates the effectiveness of third "booster" dose of COVID-19 vaccine

Harnessing the genetics of hookworms to develop next generation of PPE for combat troops

New EcoTyper tool can help identify cancer subtypes

Two new studies show how to enhance effectiveness of cancer immunotherapy

Therapeutic heparin for preventing COVID-19 deaths is four times higher than the prophylactic dose

Countermarketing messages convinces many parents to avoid buying sugary drinks for children

Forgotten antibiotic may be useful in treating severe febrile urinary tract infections

Magnus Medical receives FDA's Breakthrough Device Designation for rapid-acting technology to treat major depression

NIH study identifies distinct mechanisms of long-term HIV control in two people after treatment disruption

Study finds early fluvoxamine treatment among COVID-19 patients reduces hospitalization

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Study offers hope for a new therapeutic option for patients with severe asthma

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