Genetic News and Research

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DDX41: A unique player in myeloid leukemogenesis

A new editorial paper was published in Oncotarget's Volume 15 on July 2, 2024, entitled, "DDX41 and its unique contribution to myeloid leukemogenesis."

19 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024

Fox Chase Cancer Center researchers identify new targets for mesothelioma prevention

A new research perspective was published in Oncoscience (Volume 11) on May 23, 2024, entitled, "Targeting inflammatory factors for chemoprevention and cancer interception to tackle malignant mesothelioma."

19 Jul 2024

Marshall University receives $3.3 million grant to examine genetic mechanisms behind fentanyl addiction

Marshall University was awarded a $3.3 million grant (#R01DA057931) from the National Institute on Drug Abuse (NIDA) to examine the genetic mechanisms that underlie fentanyl addiction.

19 Jul 2024

Elite Controllers: Do their genomes hold the key to curing HIV?

Although South Africa has the largest number of people living with HIV worldwide, strides have been made in controlling the epidemic, especially in the reduction of HIV incidence, testing, and treatment. Equipped with MGI’s advanced sequencing tools and technologies, researchers from the South African Medical Research Council (SAMRC) and University of KwaZulu-Natal (UKZN) are inching closer to finding the answer to the natural control of HIV infection, leading to improved health outcomes and quality of life amongst South Africans.

From MGI 19 Jul 2024

Expanding genetic Horizons: GWAS insights from the VA Million Veterans Program

A large-scale genome-wide association study (GWAS) using data from the United States Department of Veterans Affairs (VA) Million Veterans Program (MVP) – one of the largest US-based biobanks – fills crucial gaps in our knowledge of the relationships between genes, traits, and disease across diverse populations, according to a new study.

19 Jul 2024

Tiny animals steal antibiotic secrets from bacteria to fight disease

A group of small, freshwater animals protect themselves from infections using antibiotic recipes "stolen" from bacteria, according to new research by a team from the University of Oxford, the University of Stirling and the Marine Biological Laboratory (MBL), Woods Hole.

19 Jul 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Ginseng genome unlocks secrets of medicinal benefits

A landmark study has successfully decoded the complete ginseng genome, unveiling the genetic mechanisms that govern saponin biosynthesis. This detailed genetic map illuminates the evolutionary and metabolic pathways of Panax ginseng, a staple in traditional medicine. This pivotal discovery promises to drive forward breeding initiatives and augment the plant's medicinal qualities, unlocking new possibilities for therapeutic applications.

19 Jul 2024

New insights into modified nucleoside synthesis

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis system.

19 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Diverse genetic data illuminates health disparities across populations

The majority of genetic studies focus on people of European descent, which limits the understanding of how genes influence health in other populations.

18 Jul 2024

Mobile apps and wearables show promise in easing mental health symptoms during therapy wait times

The recent surge in people seeking mental health care across the country has led to long wait times for first appointments with therapists and psychiatrists.

18 Jul 2024

Improving medication adherence beats resistance testing for better HIV outcomes in African youth

Globally, around 2.6 million children and adolescents are currently living with HIV, the majority of them in Africa.

18 Jul 2024

Common blood thinner can be repurposed as an inexpensive antidote for cobra venom

Scientists at the University of Sydney and Liverpool School of Tropical Medicine have made a remarkable discovery: a commonly used blood thinner, heparin, can be repurposed as an inexpensive antidote for cobra venom.

18 Jul 2024

Breakthrough gene therapy offers hope for Duchenne muscular dystrophy

A new gene therapy treatment for Duchenne muscular dystrophy shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles.

18 Jul 2024

CU Boulder research uncovers role of endogenous retroviruses in cancer

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago.

18 Jul 2024

First trimester COVID-19 exposure and vaccination not tied to major birth defects

Neither covid-19 infection nor vaccination during the first trimester of pregnancy is associated with increased risk of major birth defects, finds a study from Scandinavia published by The BMJ today.

18 Jul 2024

Study links circadian rhythm disruption to obesity and diabetes

Disruption of circadian rhythms and clock gene expression is linked to adverse metabolic health outcomes, including obesity and diabetes. Further research is needed to understand these relationships and their implications for treatment and prevention.

17 Jul 2024

Long-term air pollution exposure doubles psoriasis risk, study finds

Long-term exposure to air pollution and genetic predisposition significantly increase the risk of developing psoriasis, highlighting the roles of both environmental and genetic factors.

17 Jul 2024

Genetic News and Research

DDX41: A unique player in myeloid leukemogenesis

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

Fox Chase Cancer Center researchers identify new targets for mesothelioma prevention

Marshall University receives $3.3 million grant to examine genetic mechanisms behind fentanyl addiction

Elite Controllers: Do their genomes hold the key to curing HIV?

Expanding genetic Horizons: GWAS insights from the VA Million Veterans Program

Tiny animals steal antibiotic secrets from bacteria to fight disease

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Ginseng genome unlocks secrets of medicinal benefits

New insights into modified nucleoside synthesis

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Diverse genetic data illuminates health disparities across populations

Mobile apps and wearables show promise in easing mental health symptoms during therapy wait times

Improving medication adherence beats resistance testing for better HIV outcomes in African youth

Common blood thinner can be repurposed as an inexpensive antidote for cobra venom

Breakthrough gene therapy offers hope for Duchenne muscular dystrophy

CU Boulder research uncovers role of endogenous retroviruses in cancer

First trimester COVID-19 exposure and vaccination not tied to major birth defects

Study links circadian rhythm disruption to obesity and diabetes

Long-term air pollution exposure doubles psoriasis risk, study finds

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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