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A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

When a patient in the pediatric intensive care unit (PICU) develops a fever, physicians often routinely order a blood culture to identify the cause, particularly if they have reason to worry about sepsis, a life-threatening condition that occurs when chemicals released by immune system cells in the bloodstream to fight an infection trigger inflammation and shock throughout the body.

2 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Improving Medical Communication through Social Media

News-Medical interviews Dr. Benjamin Schmidt about using social media to highlight different perspectives in the medical community and improve communication between patients and doctors.

29 Apr 2022

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

All humans carry genetic variations in their DNA, called Single Nucleotide Polymorphisms (SNPs) that can underlie susceptibility to diseases such as diabetes and cancer.

28 Apr 2022

Genetic bottlenecks could impact Wyoming toads' ability to respond to new pathogens

A new study from North Carolina State University examines immune system diversity in the critically endangered Wyoming toad and finds that genetic bottlenecks could impact a species' ability to respond to new pathogens.

28 Apr 2022

Yale researchers identify immune system culprit in severe COVID cases

Yale researchers have identified a particular immune response pathway that leads to severe illness and death in people infected by the SARS-CoV-2 virus.

28 Apr 2022

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Massachusetts General Hospital researchers have developed a novel treatment strategy that has the potential to bring the life-saving benefits of chimeric antigen receptor T-cell therapy (CAR T) to patients with acute myeloid leukemia (AML) the most common form of leukemia in adults.

28 Apr 2022

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma.

28 Apr 2022

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

In a recent study published in Biomedicines, researchers explored the utility of natural killer (NK) cells in coronavirus disease 2019 (COVID-19).

28 Apr 2022

The added value of adequate immune fitness to the existing approaches to pandemic preparedness

Researchers described two studies, the CLOFIT retrospective study and the COTEST real-time study, that investigated if maintaining adequate immune fitness could significantly add to the current strategies of preparedness for COVID-19 and other pandemics.

28 Apr 2022

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the cancer - even metastatic cancer - and prevents it from recurring.

27 Apr 2022

New insight into the body’s response to tuberculosis may help design a more effective vaccine

More than 1.7 billion people - or a quarter of the world's population - are infected with Mycobacterium tuberculosis, the bacterial strain that causes tuberculosis (TB).

27 Apr 2022

Researchers identify four new target molecules for future personalized MS treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects.

27 Apr 2022

Penn scientists discover how one inflammatory disorder increases susceptibility to another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response.

27 Apr 2022

Immune System News and Research

A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Artificial circular RNAs found to bypass cellular antiviral responses

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Improving Medical Communication through Social Media

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

Genetic bottlenecks could impact Wyoming toads' ability to respond to new pathogens

Yale researchers identify immune system culprit in severe COVID cases

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

The added value of adequate immune fitness to the existing approaches to pandemic preparedness

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

New insight into the body’s response to tuberculosis may help design a more effective vaccine

Researchers identify four new target molecules for future personalized MS treatment

Penn scientists discover how one inflammatory disorder increases susceptibility to another

Research shows existence of a link between atherosclerotic plaques and the central nervous system

Genetic cause of lupus identified

Gene discovery could pave the way for new and more effective treatments for lupus

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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