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New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

New research lays the foundation for more effectively treating pediatric brain tumor

In a ground-breaking new study, scientists have uncovered the mechanics of the blood-tumor barrier, one of the most significant obstacles to improving treatment efficacy and preventing the return of cancerous cells.

1 Nov 2022

UT Southwestern study uncovers a causative signaling pathway in breast cancer

UT Southwestern researchers have identified a causative signaling pathway in breast cancer, providing potential new targets for treatment of the most common type of cancer in women.

1 Nov 2022

First preclinical model to study the pathobiology of appendiceal cancer

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year.

1 Nov 2022

EULAR points-to-consider can guide diagnostic evaluation, treatment and monitoring of SAIDs

SAIDs are a group of multi-system disorders caused by dysfunction in the innate immune system. A number of these SAIDs are mediated by a cytokine called interleukin-1 (IL-1), including the cryopyrin-associated periodic syndromes (CAPS), tumor necrosis factor receptor-associated periodic syndrome (TRAPS), mevalonate kinase deficiency (MKD), and deficiency of the IL-1 receptor antagonist (DIRA).

1 Nov 2022

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

Triple-negative breast cancer (TNBC) tumors gain immunosuppression and chemoresistance through interactions between interleukin 34 and myeloid-derived suppressor cells, researchers find.

1 Nov 2022

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.

1 Nov 2022

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases. Fortunately, HPV-positive oropharynx cancers have an improved survival rate compared to other head and neck cancers, allowing for less intensive treatment options, especially if diagnosed at early stages.

1 Nov 2022

Researchers develop special molecules that stimulate the immune system

Surgery, radiation, and chemotherapy are the three main therapies used to treat cancerous tumors. The doctoral research network 'Magicbullet::Reloaded'is investigating another approach, with 15 doctoral researchers developing special molecules that stimulate the immune system to destroy tumor cells. In a video, network members explain how doctoral researchers gain valuable experience and research opportunities as part of the network.

1 Nov 2022

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

The Breast Cancer Research Foundation (BCRF) has renewed its funding to Elisa Port, MD, and Hanna Irie, MD, PhD, to study new therapeutic approaches that target aggressive triple-negative breast cancer.

31 Oct 2022

Study expands breast cancer patient population that can benefit from PARP inhibitors

A drug approved to treat breast cancer patients with mutations in the BRCA1 or BRCA2 genes may also benefit people who have other genetic mutations.

31 Oct 2022

New system to detect cancer-related markers on CTCs

Having biopsies taken and endless tests run is nobody's idea of a good time, even if it's necessary for monitoring your health.

31 Oct 2022

Artificial intelligence-based method may help predict early-stage melanoma recurrence

Most deaths from melanoma - the most lethal form of skin cancer - occur in patients who were initially diagnosed with early-stage melanoma and then later experienced a recurrence that is typically not detected until it has spread or metastasized.

31 Oct 2022

New way of reprogramming immune cells shown to work in melanoma

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard-to-treat and devastating skin cancer, melanoma.

31 Oct 2022

New method to improve nanoparticle coating may enhance tumor targeting

A new technique to improve the coating of nanoparticles used in cancer therapy may enhance tumour targeting, a new study carried out in collaboration between the University of Eastern Finland and Anhui Medical University in China concludes.

31 Oct 2022

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

This study is led by Dr. Longtao Huangfu, and Dr. Xiaoyang Wang (Peking University Cancer Hospital & Institute). A diet of fresh fruits and vegetables may reduce the prevalence of cancers, including GC (Eusebi et al., 2020; Liu et al., 2021).

28 Oct 2022

CHG may be the most effective irrigation solution for use during surgical treatment of bone tumors

The widely used disinfectant chlorhexidine gluconate (CHG) appears to be the most effective irrigation solution for use as part of the surgical treatment of bone tumors, suggests an experimental study in The Journal of Bone & Joint Surgery.

28 Oct 2022

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

RNA, the molecule that gave rise to life, has been shown to be essential for repairing human genetic material and preventing mutations that might lead to developing cancer.

28 Oct 2022

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

A Ludwig Cancer Research study has developed a novel nanotechnology that triggers potent therapeutic anti-tumor immune responses and demonstrated its efficacy in mouse models of multiple cancers.

28 Oct 2022

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

The malignant brain tumor type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumor cells resting and insensitive to radiation treatment.

28 Oct 2022

Tumor News and Research

New control system could be used to finely tune the production of useful proteins

New research lays the foundation for more effectively treating pediatric brain tumor

UT Southwestern study uncovers a causative signaling pathway in breast cancer

First preclinical model to study the pathobiology of appendiceal cancer

EULAR points-to-consider can guide diagnostic evaluation, treatment and monitoring of SAIDs

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Researchers develop special molecules that stimulate the immune system

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

Study expands breast cancer patient population that can benefit from PARP inhibitors

New system to detect cancer-related markers on CTCs

Artificial intelligence-based method may help predict early-stage melanoma recurrence

New way of reprogramming immune cells shown to work in melanoma

New method to improve nanoparticle coating may enhance tumor targeting

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

CHG may be the most effective irrigation solution for use during surgical treatment of bone tumors

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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