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Gene abnormality found to predict childhood leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

8 Jan 2009

Latest genetic research on ADHD

A special issue of American Journal of Medical Genetics (AJMG): Part B: Neuropsychiatric Genetics presents a comprehensive overview of the latest progress in genetic research of Attention Deficit/Hyperactivity Disorder (ADHD).

7 Jan 2009

Scientists visualize the mechanism of synthesizing estrogen

The molecular details of Aromatase, the key enzyme required for the body to make estrogen, are no longer a mystery thanks to the structural biology work done by the Ghosh lab at the Hauptman-Woodward Medical Research Institute (HWI) in Buffalo, New York.

7 Jan 2009

Gene mutations found to predict acute lymphoblastic leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

7 Jan 2009

Lilly receives complete response letter for Olanzapine LAI for treatment of schizophrenia

Eli Lilly and Company has announced that it received a complete response letter from the U.S. Food and Drug Administration (FDA) for olanzapine long-acting injection (LAI) for acute and maintenance treatment of schizophrenia in adults.

7 Jan 2009

Widespread antiviral drug use can accelerate the evolution of drug resistance in viruses

Influenza's ability to resist the effects of cheap and popular antiviral agents in Asia and Russia should serve as a cautionary tale about U.S. plans to use the antiviral Tamiflu in the event of widespread avian flu infection in humans, scientists say.

7 Jan 2009

Codexis announces licensing agreement with Teva Pharmaceutical Industries

Codexis, Inc. today announced a licensing agreement with Teva Pharmaceutical Industries Ltd., to produce an important publicly-undisclosed generic product, using a proprietary Codexis biocatalyst.

7 Jan 2009

Bird flu becoming more resistant to antivirals

A new University of Colorado at Boulder study shows the resistance of the avian flu virus to a major class of antiviral drugs is increasing through positive evolutionary selection, with researchers documenting the trend in more than 30 percent of the samples tested.

7 Jan 2009

New Benzothiazepine test will catch sports cheats

Avoiding detection just got harder for drug cheats who try to use a particular range of untested, but potentially enhancing, compounds.

7 Jan 2009

Framingham and National Cholesterol Education Program tools do not accurately predict coronary heart disease

The Framingham and National Cholesterol Education Program tools, NCEP, do not accurately predict coronary heart disease, according to a study performed at the Yale University School of Medicine in New Haven, CT.

6 Jan 2009

Sequella, Inc. drug compound SQ109 selected for phase 1B clinical trial program

Sequella, Inc., a clinical-stage biopharmaceutical company focused on diseases of epidemic potential, announced today that SQ109, its lead drug candidate for the treatment of tuberculosis (TB), was the first drug approved for evaluation in a newly awarded clinical program contract to Dynport Vaccine Company LLC and Quintiles Transnational.

6 Jan 2009

People with Ala12 gene variant need to watch out for high fat in their diets

New evidence in mice bolsters the notion that a version of a gene earlier shown to protect lean people against weight gain and insulin resistance can have the opposite effect in those who eat a high-fat diet and are heavier, reveals a report in the January 7th issue of the journal Cell Metabolism, a Cell Press publication.

6 Jan 2009

New hope for leptin as a solution to obesity

The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity.

6 Jan 2009

Home visits lower likelihood of low birth weight babies

Socially disadvantaged mothers who receive home visits from trained community visitors are less likely to deliver low birth weight babies than other mothers in similar circumstances, a new study finds.

6 Jan 2009

Novel compound F15845 shows promise for angina

A compound designed to prevent chest pains in heart patients has shown promising results in animal studies, say scientists.

6 Jan 2009

Novel treatment option for obesity

A new study in the January 7th issue of Cell Metabolism , a Cell Press publication, helps to explain why obese people and animals fail to respond to leptin, a hormone produced by fat that signals the brain to stop eating.

6 Jan 2009

Apolipoprotein D protects against Alzheimer's

Do Carmo and her collaborators have successfully demonstrated the protective and reparative role of apolipoprotein D, or ApoD, in neurodegenerative diseases. Their discovery suggests interesting avenues for preventing and slowing the progression of this type of illness.

6 Jan 2009