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Mutant genes trigger AMD but may lighten the way to new treatments

According to new research in the U.S., the most common form of blindness in the elderly, age-related macular degeneration (AMD), can be attributed to just two genes which trigger the condition.

7 Mar 2006

SSRI use associated with increased risk for heart patients

In a surprising finding, patients with coronary artery disease who take commonly used antidepressant drugs may be at significantly higher risk of death, Duke University Medical Center researchers have found.

7 Mar 2006

New anti-drug program success

A newly-released study suggests that a well-designed in-school and community communication campaign really can dramatically cut marijuana and alcohol use among young teens.

7 Mar 2006

Extensive study of natalizumab

Scientists have completed an extensive study of more than 3,000 patients who received a promising anti-inflammatory drug, natalizumab, that was linked to three cases of a serious brain infection in large clinical trials halted in early 2005.

7 Mar 2006

5,000 rare diseases need drugs, but Europe only approves a handful each year

Only seven per cent of drug applications for treating people with rare diseases were approved in Europe between 2000 and 2004, despite the fact that there are currently more than 5,000 conditions needing medication.

6 Mar 2006

Next-generation drug development: risky and costly, but worth it

Generic drugs, which drive a $40 billion dollar generics industry expected to hit $60 billion by 2007, account for 53% of all prescriptions filled in the United States today.

6 Mar 2006

FDA gives greenlight for new treatment of head and neck cancer

The U.S. Food and Drug Administration has approved colon cancer drug Erbitux to treat head and neck cancer after results of a large clinical trial showed the drug prolonged survival by 20 months.

5 Mar 2006

Trials on MS drug Tysabri renews hope for sufferers

According to the results of two new trials the multiple sclerosis (MS) drug Tysabri significantly reduces the progression of the disease.

5 Mar 2006

Cannabis destroys cancer cells

Researchers investigating the role of cannabis in cancer therapy reveal it has the potential to destroy leukaemia cells, in a paper published in the March 2006 edition of Letters in Drug Design & Discovery.

1 Mar 2006

Treating orthopaedic trauma during pregnancy - most testing and treatments safe for fetuses and mothers

Pregnant women who suffer orthopaedic trauma should be diagnosed and stabilized in the same manner as any other patient, according to research published in the March 2006 issue of the Journal of the American Academy of Orthopaedic Surgeons.

1 Mar 2006

Rhodium quinones promise better drugs

By combining a common organic compound with a rare metal, a team of Brown University chemists has created a new class of molecules that have potentially important applications for the pharmaceutical, chemical and energy industries.

1 Mar 2006

Hydrogel scaffold materials used to create stable networks of blood vessels

Yale biomedical engineers have created an implantable system that can form and stabilize a functional network of fine blood vessels critical for supporting tissues in the body, according to a report in the Proceedings of the National Academy of Sciences.

1 Mar 2006

Effective oral treatment of erectile dysfunction can improve relationships

The inability to perform sexually can have a significant negative psychosocial impact on a man's overall health including depression, anxiety, and low self-esteem.

1 Mar 2006

Reaction to DTaP vaccine finds no help from ibuprofen, acetaminophen

A red splotch forms where most preschoolers get their fifth, and last, shot of the acellular diphtheria-tetanus-pertussis (DTaP) vaccine, and it can last a few days.

1 Mar 2006

Concerta used to treat ADHD may be less likely to be abused than other stimulant drugs

A team led by Massachusetts General Hospital (MGH) researchers has found that a delayed-release stimulant used to treat attention-deficit hyperactivity disorder (ADHD) may be less likely to be abused than other stimulant drugs.

1 Mar 2006

Parents are a powerful influence in keeping their teens off of drugs

And according to new data, the majority of teens say the greatest risk in using marijuana is upsetting their parents (69%), followed by losing the respect of friends and family (67.2%).

1 Mar 2006

HAART is very cost-effective

New research shows that highly active antiretroviral therapy (HAART) is very cost-effective, despite the high price tag. However, the study also shows that reimbursement to physicians treating patients with HIV is critically low, threatening patients' access to care.

1 Mar 2006

FDA shields drug companies from lawsuits

Last month, the FDA revealed its latest protective policy for drug companies in a statement that said people who believe they have been injured by drugs approved by the FDA should not be allowed to sue drug companies in state courts.

1 Mar 2006

Night blindness is a new clinical symptom of Chagas disease

"This is a new observation, a new clinical symptom of Chagas disease," said Levin, head of the Laboratory of the Molecular Biology of Chagas Disease at the University of Buenos Aires, Argentina. Levin and colleagues report their findings in the March 2006, issue of the FASEB Journal.

1 Mar 2006

Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer

A new study shows that patients whose colorectal cancer has spread to the liver who received an approach called hepatic arterial infusion (HAI) - the administration of chemotherapy directly to the liver through a pump in the abdomen - fare better than those who received traditional, intravenous chemotherapy.

1 Mar 2006