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Cooling brain prevents cell death in young mice exposed to anesthesia

New research from Washington University School of Medicine in St. Louis suggests cooling the brain may prevent the death of nerve cells that has been observed in infant mice exposed to anesthesia.

17 Nov 2008

First-ever glimpse of the cell-wall structure in three dimensions

The bacterial cell wall that is the target of potent antibiotics such as penicillin is actually made up of a thin single layer of carbohydrate chains, linked together by peptides, which wrap around the bacterium like a belt around a person, according to research conducted by scientists at the California Institute of Technology (Caltech).

17 Nov 2008

Governments urged to take broader perspective when considering whether to fund vaccines

Including quality-of-life impacts in assessments of national vaccination programs would lead to many benefits, including improved productivity and less sick leave for parents, according to an editorial co-authored by a University of New South Wales (UNSW) researcher, that has appeared in the Lancet Infectious Diseases.

17 Nov 2008

Protein enzyme BubR1 provides new understanding of processes behind cancer-cell survival and drug-resistance

A study of how one protein enzyme, BubR1, helps make sure chromosomes are equally distributed during mitosis might explain how the process of cell division goes so awry in cancer, according to researchers from Fox Chase Cancer Center.

17 Nov 2008

Scientists discover how certain antibiotics kill bacteria

A series of genetic clues led a team of Boston University biomedical engineers to uncover exactly how certain antibiotics kill bacteria.

17 Nov 2008

New and improved scientific method to forecast the demand for key anti-malarial treatments

Treating infectious diseases while meeting escalating costs to do so continues to pose worldwide challenges, with one of the main issues being the ability to provide an adequate supply of drugs to treat infectious diseases.

17 Nov 2008

'Intelligent' cancer drug development boosts success rates

A new era of intelligent cancer drug development has spurred a leap in the proportion of drugs reaching patients, according to a study by Cancer Research UK scientists published in Nature Reviews Drug Discovery.

17 Nov 2008

Scientists establish completely new route to cancer development

CANCER RESEARCH UK scientists have linked cancer clues in faulty cells to provide a new route to cancer development, reveals a study published in Developmental Cell.

17 Nov 2008

Scientists gain insight into the cause and possible treatment of motor neurone disease

BBSRC-funded researchers at UCL along with collaborators at King's College London have identified a molecule that could be the key to understanding the cause of neurodegenerative diseases such as motor neurone disease (MND).

17 Nov 2008

Blood exosomes shown to contain tumor-specific genetic information for brain cancer

Tiny vesicles called exosomes released into the bloodstream from aggressive brain tumors contain genetic signatures that may help guide future diagnosis and treatment of this deadly disease.

17 Nov 2008

University of Illinois at Chicago joins international research effort on autism

Researchers at the University of Illinois at Chicago are taking part in an international effort to gather DNA samples from 2,000 autism patients and their families over the next three years.

16 Nov 2008

Scientists find intra cellular pathway driving a deadly sub-type of breast cancer

An intra cellular pathway not previously linked to breast cancer is driving a sub-type of the disease that is highly lethal and disproportionately over-represented in African American women.

16 Nov 2008

Microvesicles released from glioblastoma cells carry information that may guide treatment

Microvesicles - tiny membrane-covered sacs - released from glioblastoma cells contain molecules that may provide data that can guide treatment of the deadly brain tumor.

16 Nov 2008

New research reveals key steps in HIV's assault on the brain

Scientists have unraveled in unprecedented detail the cascade of events that go wrong in brain cells affected by HIV, a virus whose assault on the nervous system continues unabated despite antiviral medications that can keep the virus at bay for years in the rest of the body.

16 Nov 2008

PEA-15 protein points to potential targeted approach for ovarian cancer

A protein known to inhibit the growth of ovarian cancer works in part by forcing cancer cells to eat themselves until they die, researchers at The University of Texas M. D. Anderson Cancer Center report in the Nov. 15 issue of Cancer Research .

16 Nov 2008

Previously unknown regulatory step during HIV replication provides potential new target for HIV/AIDS therapy

A previously unknown regulatory step during human immunodeficiency (HIV) replication provides a potentially valuable new target for HIV/AIDS therapy, report researchers at the Salk Institute for Biological Studies and the University of Wisconsin, Madison.

16 Nov 2008

Aspirin lowers PSA levels

The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is significantly associated with lower PSA levels, especially among men with prostate cancer, say researchers at Vanderbilt University.

16 Nov 2008

Vigabatrin offers hope for treating relapse to methamphetamine abuse

A new study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory suggests that vigabatrin (a.k.a. gamma vinyl-GABA, or GVG) blocks drug-seeking behavior in animals previously trained to associate methamphetamine with a particular environment.

16 Nov 2008

Higher levels of blood phosphate may be a previously unidentified and modifiable cardiovascular risk factor

Healthy adults with higher levels of phosphate in the blood are more likely to have increased levels of calcium in the coronary arteries-a key indicator of atherosclerosis and future cardiovascular disease risk, reports a study in the February 2009 issue of the Journal of the American Society of Nephrology (JASN).

16 Nov 2008

Drug-related preference in cocaine addiction extends to images

When given a choice between viewing pictures of cocaine and a variety of other images, cocaine addicted individuals, as compared to healthy, non-addicted research subjects, show a clear preference for the drug-related images.

16 Nov 2008

Drugs News and Research

Cooling brain prevents cell death in young mice exposed to anesthesia

First-ever glimpse of the cell-wall structure in three dimensions

Governments urged to take broader perspective when considering whether to fund vaccines

Protein enzyme BubR1 provides new understanding of processes behind cancer-cell survival and drug-resistance

Scientists discover how certain antibiotics kill bacteria

New and improved scientific method to forecast the demand for key anti-malarial treatments

'Intelligent' cancer drug development boosts success rates

Scientists establish completely new route to cancer development

Scientists gain insight into the cause and possible treatment of motor neurone disease

Blood exosomes shown to contain tumor-specific genetic information for brain cancer

University of Illinois at Chicago joins international research effort on autism

Scientists find intra cellular pathway driving a deadly sub-type of breast cancer

Microvesicles released from glioblastoma cells carry information that may guide treatment

New research reveals key steps in HIV's assault on the brain

PEA-15 protein points to potential targeted approach for ovarian cancer

Previously unknown regulatory step during HIV replication provides potential new target for HIV/AIDS therapy

Aspirin lowers PSA levels

Vigabatrin offers hope for treating relapse to methamphetamine abuse

Higher levels of blood phosphate may be a previously unidentified and modifiable cardiovascular risk factor

Drug-related preference in cocaine addiction extends to images

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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