Drugs News and Research

RSS

Rituximab maintenance therapy dramatically improves survival for patients with lymphoma

Two years of maintenance therapy with rituximab dramatically improves the chances of survival for patients suffering from one of the most frequent forms of lymphoma, indolent non-Hodgkin's Lymphoma (NHL).

14 Feb 2006

Hormone replacement therapy protects against heart disease in younger women

According to a new study hormone replacement therapy using estrogen does not appear to protect postmenopausal women from heart disease.

14 Feb 2006

Almost half of heart attacks are not recognised

According to Dutch researchers almost fifty percent of heart attacks are not recognised as such.

14 Feb 2006

Gene therapy cures depressed mice

Researchers in the U.S. say that deleting a specific gene in the brain of mice that have been conditioned to be depressed, has the same effect as antidepressants.

13 Feb 2006

So much for openness and enhanced oversight at FDA drug safety board!

The Drug Safety Oversight Board, created in February 2005, was originally introduced as a measure to speed up and help regulators respond to signs of unexpected side effects following a new drug hitting the market.

13 Feb 2006

Acne drug which causes birth defects too hard to monitor

According to the birth watchdog group the March of Dimes, preventing birth defects from a widely used acne drug is too heavy a burden on doctors, patients and pharmacists.

13 Feb 2006

Genzyme launches test to monitor Gleevec resistance

Genzyme Corporation has announced the availability of an important new test to monitor drug resistance in chronic myeloid leukemia (CML) patients who are treated with Gleevec (imatinib mesylate).

13 Feb 2006

Girls are catching up with boys in use of illicit substances

Despite commonly held beliefs that boys are at higher risk for using illegal substances, data indicate that girls have caught up with boys in illicit drug and alcohol use and have actually surpassed boys in cigarette and prescription drug use. There are also more girls who are new users of substances than boys.

13 Feb 2006

Sirolimus reduces risk of cancer in kidney transplant patients

A new study published in this month's issue of the Journal of the American Society of Nephrology shows that the risk of cancer in kidney transplant recipients was reduced by more than 50% at five years post transplantation in those patients who were treated with sirolimus following withdrawal of cyclosporine at three months.

13 Feb 2006

Statins show beneficial effect on rheumatoid arthritis

Statins, a class of drugs widely used to treat high cholesterol, have also recently been studied for their potential role in inflammation and other cell processes, including immune response.

13 Feb 2006

Stopping antidepressants during pregnancy may lead to relapse

Women who stop taking antidepressant medications during pregnancy are at a five times greater risk for recurrence of depression than are women who continue taking their medication throughout their pregnancies, according to a multi-institutional study published in the Journal of the American Medical Association.

13 Feb 2006

Cellular discovery suggests possibilities for drug therapy for kidney disease

Scientists at the University of California, Santa Barbara have reported a discovery at the cellular level that suggests possibilities for drug therapy for kidney disease.

13 Feb 2006

Common genetic variation increases SIDS risk in African Americans

About five percent of deaths from SIDS (sudden infant death syndrome) in African Americans can be traced to defects in one gene and half of those deaths result from a common genetic variation that increases an infant's risk of developing an abnormal heart rhythm during times of environmental stress

13 Feb 2006

Chink in cancer's armor

Much as the famed starship Enterprise would deploy a deflector shield to evade enemy attack, tumor cells are capable of switching on a molecular force field of their own to fend off treatments aimed at killing them. Now University of Florida researchers have found a chink in their armor.

13 Feb 2006

Drugs formerly contraindicated for inflammatory bowel disease prove beneficial for pain relief

According to two studies published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, prescription painkillers are effective in easing the pain of patients with dormant inflammatory bowel disease (IBD) and are not likely to cause symptom flare-ups in IBD patients in remissions

12 Feb 2006

Gut protein protects against infection and intestinal breakdown

A protein that binds to bile in the small intestine may hold the key to preventing infection and intestinal breakdown in people with conditions such as obstructive jaundice or irritable bowel syndrome, researchers at UT Southwestern Medical Center have discovered.

12 Feb 2006

Heart risk warning wanted on ADHD drugs

A U.S. advisory panel has recommended that drugs used by millions to treat attention deficit hyperactivity disorder (ADHD), should carry a warning of the risk of heart problems.

12 Feb 2006

Use of antidepressants during pregnancy linked to neonatal abstinence syndrome in infants

Almost one-third of 60 newborn infants whose mothers took antidepressants during pregnancy experienced neonatal abstinence syndrome, a type of withdrawal with symptoms that include high-pitched crying, tremors and disturbed sleep, according to a study in the February issue of Archives of Pediatrics & Adolescent Medicine.

9 Feb 2006

First solid data on health effects of a low-fat diet

Adopting a low-fat diet in later life and following such a regimen for nearly a decade does not appear to have a significant impact on reducing the overall risk of breast cancer, colorectal cancer or heart disease, according to a Women's Health Initiative study that involved nearly 50,000 postmenopausal women across the United States.

9 Feb 2006

Researchers define a new "first step" that initiates sepsis

A Mayo Clinic research team has challenged the accepted theory on the cause of sepsis -- a condition in which the body's cells generate fever, shock and often death. Sepsis is thought to occur when poisons from bacterial infection interfere with the cells.

9 Feb 2006