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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Post-illness metabolomic and gut-microbiome profiles in community-dwelling participants with SARS-CoV-2

Researchers explored post-illness gut-microbiome and metabolomic profiles of community COVID-19 cases and individuals with non-COVID-19 illnesses of prolonged duration.

15 Aug 2022

Why is COVID-19 more severe in people older than 50?

A new study reports that the reduced efficiency of the immune response against SARS-CoV-2 could be due to the reduced diversity of both B- and T-cells.

14 Aug 2022

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Researchers compare the length spectra of sperm mitochondrial DNA deletions in two seasons with varied air pollution levels.

14 Aug 2022

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases.

12 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

What is the impact of heat treatment on monkeypox virus?

In newly released research, investigators determined the inactivation of monkeypox virus (MPXV) by heat treatment.

12 Aug 2022

What is the impact of COVID-19 on male reproductive health?

In a recent study, researchers assessed male reproductive health three months after COVID-19 infection.

12 Aug 2022

How should we react to the global monkeypox outbreak?

In a new study, researchers assessed the various aspects of the global monkeypox outbreak.

12 Aug 2022

Novel zoonotic Langya virus identified in China

Scientists discuss their discovery of the novel Langya henipavirus in eastern China.

11 Aug 2022

Portable diagnostic device deployed in sub-Saharan Africa to identify cases of Kaposi sarcoma

A portable diagnostic device designed by researchers at Cornell Engineering and Weill Cornell Medicine has been deployed in clinical tests in Uganda to identify cases of Kaposi sarcoma, a common yet difficult-to-detect cancer that often signals the presence of HIV infection.

11 Aug 2022

Wastewater surveillance expanded to detect the presence of monkeypox

An ongoing program that monitors wastewater for the presence of SARS-CoV-2 and which has effectively predicted subsequent surges in COVID-19 cases in San Diego has been expanded to detect the presence of monkeypox.

11 Aug 2022

Transposable element controls the immune system to favor host survival during virus infection

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection.

11 Aug 2022

Novel model reveals how genomic instability arises in histologically benign tissue

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically, over time. This has been made possible using a new technique called spatial transcriptomics, which allows scientists to see what genetic changes take place without breaking up the tissue they're looking at.

11 Aug 2022

Study aims to understand how female fertility is established at the molecular level

Fertility is finite for mammalian females. From birth, females possess a limited number of primordial follicles, collectively called the ovarian reserve. Within each follicle is an oocyte that eventually becomes an egg. But with age, the follicles in the ovarian reserve decrease.

11 Aug 2022

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Scientists discover new target for treatment of premature aging disorders

A stretch of DNA that hops around the human genome plays a role in premature aging disorders, scientists at the Salk Institute and King Abdullah University of Science and Technology in Saudi Arabia have discovered.

10 Aug 2022

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

In a study recently published in Cancer Research, a journal of the American Association for Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center School of Medicine Cancer Center, sought to expand upon his lab's previous research that showed ALT tumors identified by a biomarker known as C-circles share a common biology that confers vulnerabilities to be exploited for cancer therapy.

10 Aug 2022

Scientists conduct comparative analysis of monkeypox virus profilin-like proteins and human profilin proteins

In a new study, researchers explored monkeypox virus proteomics and structural characteristics of the A42R protein, the only MPXV protein in the RCSB PDB (protein data bank) and the only profilin-like protein of poxviruses with known structure.

10 Aug 2022

What is the correlation between monkeypox viral DNA and infectivity in clinical samples?

In a new study, researchers investigated the correlation between monkeypox virus (MPXV) infectivity and viral DNA content in clinical specimens.

10 Aug 2022

DNA News and Research

Further Reading

Post-illness metabolomic and gut-microbiome profiles in community-dwelling participants with SARS-CoV-2

Why is COVID-19 more severe in people older than 50?

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

What is the impact of heat treatment on monkeypox virus?

What is the impact of COVID-19 on male reproductive health?

How should we react to the global monkeypox outbreak?

Novel zoonotic Langya virus identified in China

Portable diagnostic device deployed in sub-Saharan Africa to identify cases of Kaposi sarcoma

Wastewater surveillance expanded to detect the presence of monkeypox

Transposable element controls the immune system to favor host survival during virus infection

Novel model reveals how genomic instability arises in histologically benign tissue

Study aims to understand how female fertility is established at the molecular level

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Scientists discover new target for treatment of premature aging disorders

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

Scientists conduct comparative analysis of monkeypox virus profilin-like proteins and human profilin proteins

What is the correlation between monkeypox viral DNA and infectivity in clinical samples?

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