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Rapid hand-held troponin blood test for heart attack diagnosis launched by Philips

Chest pain patients presenting at the emergency department are set to benefit from a major development by Royal Philips. The company today announced that it has CE marked its cardiac troponin I (cTnI) blood test on the Minicare I-20 handheld device. Minicare cTnI delivers its lab comparable test results in less than 10 minutes near the patient, reducing the time for the physician to decide on treatment.

From Philips Healthcare 25 May 2016

Diet-based therapy may improve quality of life in IBS patients

A change in diet can improve the lives of those diagnosed with a common, but hard-to-treat gut disorder.

25 May 2016

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine revealed that triple-negative breast cancer (TNBC), which has generally been unresponsive to hormone receptor-targeted treatments, can indeed be treated using vitamin D and androgen receptor-targeted therapy.

24 May 2016

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

An endoscopist's knowledge of a positive Cologuard test improves colonoscopy performance, according to a poster presentation at last week's Digestive Disease Week conference.

24 May 2016

New microfluidic device helps extract rare target cells from background cells

A team of researchers from University of Cincinnati in Cincinnati, OH have developed a novel microfluidic device, which combines the inertial effect of fluid and microscale vortices generated in microchambers, to achieve simultaneous double sorting of rare target cells and removal of background cells.

23 May 2016

Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma.

21 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.

19 May 2016

MSF responds to Lord O'Neill's recommendations on how to defeat drug resistance and superbugs

The O'Neill report confirms what MSF has long voiced. The pharmaceutical industry’s system for researching and developing medicines is not always delivering the drugs, vaccines and diagnostics needed. When they are developed, they are often unaffordable or not suitable for the people who need them most

19 May 2016

ProBioGen will license GlymaxX® to Thermo Fisher Scientific for use in developing allergy diagnostics

ProBioGen, a leading specialist for contract development and manufacturing of complex glycoproteins and corresponding technologies, today announced that Thermo Fisher Scientific has licensed its GlymaxX® technology for use in development of allergy diagnostics.

19 May 2016

Research shows close similarities of canine models of human rare disorders

Professor Hannes Lohi's research group at the University of Helsinki has discovered three novel canine genes for Caffey, Raine and van den Ende-Gupta syndromes. Research reveals close similarities of the canine models of human rare disorders and highlights the potential of comparative research approach for the development of rare disease diagnostics and treatments.

18 May 2016

Biovica acquires cSens AB - creating opportunities for solving cancer diagnostic challenges

Biovica has acquired cSens AB, a company that has developed a PCR-based platform for the analysis of serum thymidine kinase (TK) enzyme activity, which correspond to tumor proliferation and cancer aggressiveness.

18 May 2016

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Ipsen S.A., a global specialty-driven pharmaceutical company, and the Institute of Molecular and Cell Biology (IMCB), a research institute under the aegis of the Agency for Science, Technology and Research (A*STAR), Singapore, today announced the signature of a research partnership to study the intracellular trafficking of botulinum neurotoxins (BoNTs) within neurons.

16 May 2016

New optimised PCR tests for reliable diagnosis of Zika virus

DZIF scientists from the University of Bonn have shown that not all conventional Zika virus molecular diagnostic tests for are sufficiently reliable. They developed optimised assays and a control for quantifying viruses in blood and urine.

13 May 2016

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Myocardial fibrosis could be a future therapeutic target after researchers found it correlated with adverse cardiovascular outcomes in patients with obstructive sleep apnoea (OSA) referred for cardiac magnetic resonance (CMR).

13 May 2016

Novel rapid diagnostic test and shorter treatment with better outcomes may benefit MDR-TB patients

New WHO recommendations aim to speed up detection and improve treatment outcomes for multidrug resistant tuberculosis (MDR-TB) through use of a novel rapid diagnostic test and a shorter, cheaper treatment regimen.

12 May 2016

New IsoPSA test identifies molecular structural changes in protein biomarkers to detect prostate cancer

A promising new test is detecting prostate cancer more precisely than current tests, by identifying molecular changes in the prostate specific antigen (PSA) protein, according to Cleveland Clinic research presented today at the American Urological Association annual meeting.

12 May 2016

Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

Researchers at Tufts University have stabilized blood samples for long periods of time without refrigeration and at high temperatures by encapsulating them in air-dried silk protein.

11 May 2016

New NICE guidance recommends use of Roche Diagnostics’ new pre-eclampsia test

Obstetricians and midwives are today welcoming the publication of new NICE guidance recommending the use of a new test from Roche Diagnostics that can rule-out the development of the life threatening condition, pre-eclampsia, within one week in pregnant women.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Diagnostics News and Research

Rapid hand-held troponin blood test for heart attack diagnosis launched by Philips

Diet-based therapy may improve quality of life in IBS patients

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

New microfluidic device helps extract rare target cells from background cells

Phase I study of triple drug combination shows promise in multiple myeloma patients

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

MSF responds to Lord O'Neill's recommendations on how to defeat drug resistance and superbugs

ProBioGen will license GlymaxX® to Thermo Fisher Scientific for use in developing allergy diagnostics

Research shows close similarities of canine models of human rare disorders

Biovica acquires cSens AB - creating opportunities for solving cancer diagnostic challenges

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

New optimised PCR tests for reliable diagnosis of Zika virus

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Novel rapid diagnostic test and shorter treatment with better outcomes may benefit MDR-TB patients

New IsoPSA test identifies molecular structural changes in protein biomarkers to detect prostate cancer

Air-dried silk protein encapsulation can stabilize blood samples for long periods of time

New NICE guidance recommends use of Roche Diagnostics’ new pre-eclampsia test

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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