Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Research uncovers defective process in patients with autosomal dominant polycystic kidney disease

New research has uncovered a process that is defective in patients with autosomal dominant polycystic kidney disease, a common cause of kidney failure. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), point to a new potential strategy for preventing and treating the disease.

6 Sep 2013

New gene that causes cystic kidneys in children, young adults identified

Sylvia Hoff, a graduate student from the Spemann Graduate School of Biology and Medicine, has identified a new gene that causes cystic kidneys in children and young adults.

6 Sep 2013

Multiple risk factors eliminate impact of AF on stroke risk, but more research is needed

Dr Benn Christiansen said: "We know that atrial fibrillation increases the risk of ischemic stroke. And in patients with atrial fibrillation or previous ischemic stroke, the risk of stroke increases with the number of risk factors.

5 Sep 2013

Blood levels of cystatin C strengthen association between kidney function and risks of renal disease

A new, international study from the Chronic Kidney Disease Prognosis Consortium found that use of blood levels of cystatin C to estimate kidney function—alone or in combination with creatinine—strengthens the association between kidney function and risks of death and end-stage renal disease.

5 Sep 2013

Ultragenyx, Kyowa Hakko Kirin To Develop Rare Bone Disease-Fighting Mab

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4 Sep 2013

Study: Nearly 12% of Chinese adults have diabetes and about 50% at risk of developing the disease

A study based on a nationally representative sample of adults in China in 2010 indicates that nearly 12 percent of Chinese adults had diabetes and the prevalence of prediabetes was about 50 percent, according to a study in the September 4 issue of JAMA.

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

Researchers from Brigham and Women's Hospital (BWH) have developed a risk score calculation that can help predict which patients with rhabdomyolysis (a condition that occurs due to muscle damage) may be at risk for the severe complication of kidney failure or death.

3 Sep 2013

Insomnia linked to GERD in nonalcoholic fatty liver disease

Insomnia appears to be relatively common in patients with nonalcoholic fatty liver disease and may occur, at least in part, as a result of gastroesophageal reflux disease symptoms, report researchers.

2 Sep 2013

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Patients with type 2 diabetes and high cardiovascular risk due to recent acute coronary syndromes had similar rates of cardiovascular events when treated with the anti-diabetic agent alogliptin compared to placebo according to results of the Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care trial presented at the European Society of Cardiology Congress.

2 Sep 2013

Research roundup: Assessing new hospital observation rule; doctors' view of DNR orders for kids

Hospitalized patients in the United States are increasingly placed on "observation status." The Centers for Medicare & Medicaid Services (CMS) state that observation should rarely exceed 48 hours.

31 Aug 2013

After voting to cut payments to dialysis clinics, many lawmakers seek a reversal

On Capitol Hill, some lawmakers are rethinking the Medicare policy for kidney patients because clinics argue they may have to close or cut services. Elsewhere, the president of the American Medical Association is optimistic Congress will change Medicare's payment formula and a Republican senator wants all congressional staff to get coverage in Obamacare's exchanges.

30 Aug 2013

GW researcher to receive $1.3M NIDDK grant to study how type 2 diabetes develops

A George Washington University researcher will receive $1.3 million over the next five years from the National Institute of Diabetes and Digestive and Kidney Diseases for research that will help better understand how type 2 diabetes develops, possibly informing the development of novel treatments to reverse the disease.

30 Aug 2013

Urinary protein may be early warning sign regarding patients' cognitive abilities

The presence of protein in the urine may be a marker of risk for future cognitive decline in patients with type 2 diabetes and normal kidney function, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

30 Aug 2013

Socioeconomic status more important barrier to living kidney donation than cultural factors

Socioeconomic status is a more important barrier to living kidney donation than cultural factors, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings may be useful for determining ways to increase living kidney donation in the United States.

30 Aug 2013

Researchers discover new gene mutations which cause devastating mitochondrial disorders

Researchers have identified a novel disease gene in which mutations cause rare but devastating genetic diseases known as mitochondrial disorders.

30 Aug 2013

Study points to potential new therapeutic target for preventing birth defects in women with diabetes

A research team at the University of Maryland School of Medicine has identified a cell signaling pathway which plays a significant role in causing developmental defects of the fetal spinal cord and brain in babies of women with diabetes.

29 Aug 2013

Findings support partial nephrectomy for T1b RCC

Partial nephrectomy and radical nephrectomy provide comparable cancer control for T1b renal cell carcinoma, yet use of the less radical approach has remained limited in the USA over recent years, study results show.

28 Aug 2013

Researchers develop ddPCR technology to quantify rejection biomarker in organ transplant injury

A recently reported blood test for the early detection of organ transplant injury could enable more timely therapeutic intervention in transplant patients and thus help to avoid longer term damage. As described by scientists at the University Medical Center G-ttingen and Chronix Biomedical, a molecular diagnostics company, the new method uses Bio-Rad Laboratories' Droplet Digital PCR (ddPCR-) technology to overcome the obstacles of earlier tests, which were both time-consuming and costly.

28 Aug 2013

New technique using ice slush and robotic surgery to remove large kidney stone

A first-ever technique using ice slush and minimally invasive robotic surgery to remove a particularly large type of kidney stone has been reported by urologists at Henry Ford Hospital.

28 Aug 2013

Nephrology News and Research

Further Reading

Research uncovers defective process in patients with autosomal dominant polycystic kidney disease

New gene that causes cystic kidneys in children, young adults identified

Multiple risk factors eliminate impact of AF on stroke risk, but more research is needed

Blood levels of cystatin C strengthen association between kidney function and risks of renal disease

Ultragenyx, Kyowa Hakko Kirin To Develop Rare Bone Disease-Fighting Mab

Study: Nearly 12% of Chinese adults have diabetes and about 50% at risk of developing the disease

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

Insomnia linked to GERD in nonalcoholic fatty liver disease

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Research roundup: Assessing new hospital observation rule; doctors' view of DNR orders for kids

After voting to cut payments to dialysis clinics, many lawmakers seek a reversal

GW researcher to receive $1.3M NIDDK grant to study how type 2 diabetes develops

Urinary protein may be early warning sign regarding patients' cognitive abilities

Socioeconomic status more important barrier to living kidney donation than cultural factors

Researchers discover new gene mutations which cause devastating mitochondrial disorders

Study points to potential new therapeutic target for preventing birth defects in women with diabetes

Findings support partial nephrectomy for T1b RCC

Researchers develop ddPCR technology to quantify rejection biomarker in organ transplant injury

New technique using ice slush and robotic surgery to remove large kidney stone

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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Evaluating new approaches for rare disease genomics

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