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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

New research, available as a preprint on the bioRxiv* server, has focused on the role played by T cell immunity, particularly CD8+ cytotoxic T cells, on preventing lethal infection with SARS-CoV-2 in mice infused with peptide-loaded antigen-presenting dendritic cells (DCs).

19 Aug 2021

Scientists identify a potent neutralizing nanobody against SARS-CoV-1

In a recently published article in the journal Virologica Sinica, scientists have described the development and validation of a potent nanobody that targets the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus (SARS-CoV). The nanobody efficiently and specifically blocks the interaction between RBD and angiotensin-converting enzyme 2 (ACE2) and neutralizes the virus.

19 Aug 2021

White-tailed deer are highly susceptible to SARS-CoV-2 infection

The SARS-CoV-2 virus has been shown to infect a wide range of animals naturally and experimentally, and prior studies indicate deer are susceptible to infection. White-tailed deer (Odocoileus virginianus) fawns have been found to be susceptible to SARS-CoV-2.

19 Aug 2021

Genomic surveillance is vital to combat COVID-19

Although the development and increasingly widespread availability of effective and safe vaccines provides the greatest hope for the future recovery from the increasingly devastating COVID-19 pandemic, genomic surveillance is emerging as a vital necessity to achieve effective mitigation and containment.

18 Aug 2021

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

A new study has determined the production of the SARS-CoV-2 SP-dependent ORF8.

18 Aug 2021

Severe COVID-19 characterized by phosphorylation of STAT1

A new study reports an enhanced expression of STAT1 in mild and severely infected COVID-19 patients as compared to controls

18 Aug 2021

Study examines prevalence of neutralizing antibodies to HCoV-NL63 in healthy adults in Australia

A new study has been published in the MPDI journal Viruses, which focuses on determining the seroprevalence of neutralizing antibodies against HCoV-NL63, in healthy adults, in a cross-sectional study.

18 Aug 2021

Scientists propose innovative method to test the effectiveness of coronavirus medicines

South Ural State University scientists have proposed an innovative method for testing the effectiveness of medicines for coronavirus. According to the researchers, it is necessary to focus on the maximum coincidence of the ligand and the receptor. The results of the work have been published in the highly-rated journal "Molecules"(Q1).

18 Aug 2021

ELRIG UK Announces Drug Discovery 2021 Event to Host SLAS’s Innovation AveNEW

The European Laboratory Research & Innovation Group today announced the programme details for Drug Discovery 2021.

From Society for Laboratory Automation and Screening (SLAS) 18 Aug 2021

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

A new study suggests a new coronavirus test developed by scientists from the University of Washington and the Brotman Baty Institute for Precision Medicine produces faster and more sensitive results than conventional PCR tests to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA.

18 Aug 2021

Promega's complete workflow quickly provides a snapshot of community-wide infection rates using wastewater samples

A complete workflow developed by Promega Corporation enables wastewater testing laboratories, including public health organizations, to quickly assess the health of entire communities from a single sample.

18 Aug 2021

P681R spike mutation enhances replication efficiency of SARS-CoV-2 delta variant

A team of scientists from the University of Texas, USA, has recently revealed that the P681R spike mutation is responsible for increased infectivity of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The P681R spike mutation increases the replication of the delta variant by increasing the dissociation of S1 and S2 subunits at the furin cleavage site. The study is currently available on the bioRxiv* preprint server.

18 Aug 2021

Researchers confirm the speed, simplicity and accuracy of new COVID-19 testing method

Researchers from the University of Birmingham, U.K., have confirmed the speed, accuracy, and simplicity of a novel, a highly sensitive testing method for COVID-19 that can be deployed at entertainment venues, airport arrival terminals, and in remote settings where clinical testing laboratories are not available.

17 Aug 2021

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Now, a new study posted to the bioRxiv* preprint server focuses on functional immune memory to SARS-CoV-2, up to nine months in a Southeast Asian cohort, in the absence of re-infection.

16 Aug 2021

NIH scientists develop new sample preparation method to detect SARS-CoV-2

Scientists at the National Institutes of Health (NIH) have developed a new sample preparation method to detect SARS-Cov-2, the virus that causes COVID-19.

16 Aug 2021

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Messenger-RNA (mRNA) vaccines against the coronavirus that causes COVID-19 provoke a swift and strong response by the immune system's T cells - the heavy armor of the immune system - according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2021

The newest disease detection tool for covid and beyond: Poop

Since reopening campus at the University of California-San Diego last summer, university officials have relied on the tried-and-true public health strategies of testing and contact tracing. But they have also added a new tool to their arsenal: excrement.

16 Aug 2021

New system combines computer software and cryo-EM to determine 3D structures of RNA-only molecules

The single-stranded genetic material RNA is best known for guiding the assembly of proteins in our cells and carrying the genetic code for viruses like SARS-CoV-2 and HIV.

16 Aug 2021

Direct evidence in hamsters shows SARS-CoV-2 is airborne

Evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be transmitted without contact by respiratory droplets and aerosols bearing the virus when coughing, sneezing, speaking, and breathing. The virus has been cultured from aerosols collected nearby COVID-19 patients, and such aerosols can linger in still air for hours.

15 Aug 2021

Enzyme acts as a sensor to find the hiding spots of viruses

While some types of RNA viruses cloak themselves to hide inside a cell and create copies of themselves, a "detective enzyme" might be attuned to their whereabouts. A slight variation in their genomic code gives some people's cells the capacity to produce this sensor.

14 Aug 2021

RNA News and Research

Further Reading

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

Scientists identify a potent neutralizing nanobody against SARS-CoV-1

White-tailed deer are highly susceptible to SARS-CoV-2 infection

Genomic surveillance is vital to combat COVID-19

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

Severe COVID-19 characterized by phosphorylation of STAT1

Study examines prevalence of neutralizing antibodies to HCoV-NL63 in healthy adults in Australia

Scientists propose innovative method to test the effectiveness of coronavirus medicines

ELRIG UK Announces Drug Discovery 2021 Event to Host SLAS’s Innovation AveNEW

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

Promega's complete workflow quickly provides a snapshot of community-wide infection rates using wastewater samples

P681R spike mutation enhances replication efficiency of SARS-CoV-2 delta variant

Researchers confirm the speed, simplicity and accuracy of new COVID-19 testing method

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

NIH scientists develop new sample preparation method to detect SARS-CoV-2

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

The newest disease detection tool for covid and beyond: Poop

New system combines computer software and cryo-EM to determine 3D structures of RNA-only molecules

Direct evidence in hamsters shows SARS-CoV-2 is airborne

Enzyme acts as a sensor to find the hiding spots of viruses

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