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Pathways to clinical goals speeds cancer therapy approval

Although cancer remains a leading cause of death in America, it can take up to 12 years to bring a new anti-cancer agent before the FDA and the success rate for approval is only five to 10 percent. That means many research hours and dollars are wasted chasing avenues that will not bring fruit.

15 Sep 2008

Newer atypical antipsychotic medications no better than older drug in treating child and adolescent schizophrenia

Two newer atypical antipsychotic medications were no more effective than an older conventional antipsychotic in treating child and adolescent schizophrenia and may lead to more metabolic side effects, according to a new study funded by the National Institutes of Health's National Institute of Mental Health (NIMH).

15 Sep 2008

Inherited one-hit gene mutation provides new opportunity for colon cancer prevention

More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer.

15 Sep 2008

European disparities in access to cancer drugs

New research has highlighted stark disparities in access to the latest cancer drugs across European Union nations, according to data presented at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm.

15 Sep 2008

Woman dies after being scratched by a wild rat

As a rule leptospirosis victims experience severe headaches and flu-like symptoms but the severe form which is Weil's disease, causes jaundice and liver damage, and can be fatal - but it usually only affects 10% of leptospirosis victims.

15 Sep 2008

Experts say thousands at risk for heart disease go unchecked

Australian experts say thousands at risk for heart disease go unchecked and are not getting the drugs which protect them.

15 Sep 2008

Staph infection a possible suspect in some SIDS cases

Australian researchers believe that some cases of sudden infant death syndrome (SIDS) may be caused by the bacterial infection Staphylococcus aureus (S. aureus).

15 Sep 2008

Uganda plans survey to determine prevalence of MDR-TB, health official says

Uganda this year plans to conduct a survey to determine the prevalence of multi-drug resistant tuberculosis in the country, National Leprosy and TB program manager Francis Adatu said Wednesday, the Monitor reports.

15 Sep 2008

New cannabis-like drugs could block pain without affecting brain

A new type of drug could alleviate pain in a similar way to cannabis without affecting the brain, according to a new study published in the journal Pain on Monday 15 September.

15 Sep 2008

Keppra XR approved in the U.S. for partial onset seizures

UCB announced today that the U.S. Food and Drug Administration (FDA) has approved Keppra XR (levetiracetam extended-release tablets) for use as an add-on to other antiepileptic treatments for people with partial onset seizures who are 16 years of age and older. Keppra XR is expected to be available in U.S. pharmacies at the end of September 2008.

15 Sep 2008

30 years on from Alma-Ata and the pendulum is swinging back to primary health care

Thirty years on from the signing of the historic Alma-Ata declaration, the famous rallying call to the global health community, the concept of Primary Health Care, which lay at its heart, is back on the global agenda.

15 Sep 2008

Domainex has core intellectual property rights granted for Europe

Domainex Ltd (Domainex), an innovative biopharmaceutical company, today announced the grant of European Patent No.1442134 for its Combinatorial Domain Hunting (CDH) Technology.

From Domainex 14 Sep 2008

Key component of chronic obstructive pulmonary disease identified

For the first time, researchers have demonstrated a close correlation between the decline in a key component of the lung's antioxidant defense system and the progression of chronic obstructive pulmonary disease (COPD) in humans.

14 Sep 2008

Anti-inflammatory drugs may mask prostate cancer marker

Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, may reduce serum levels of the prostate biomarker, PSA (prostate specific antigen), and hence may alter the detection of prostate cancer in individuals who take these medications.

14 Sep 2008

Health response launched for Haiti

WHO and its partners urgently need US$ 4.2 million to provide health care for many of the 800,000 people - including children and pregnant women - affected by successive tropical storms in Haiti.

14 Sep 2008

Scientists develop nanometer-sized 'cargo ships' to target and destroy tumors

Scientists have developed nanometer-sized 'cargo ships' that can sail throughout the body via the bloodstream without immediate detection from the body's immune radar system and ferry their cargo of anti-cancer drugs and markers into tumors that might otherwise go untreated or undetected.

11 Sep 2008

Naltrexone-derived pyridomorphinan shows promise for treatment of alcoholism

Southern Research Institute and Gallo Research Center today announced that peer-reviewed results from a study testing Naltrexone-derived pyridomorphinan (SoRI-9409) will be published in the December 2008 issue of the journal Biological Psychiatry.

11 Sep 2008

Drug-resistant plague - A bioterrorism concern?

The bacterium responsible for the "Black Plague," which led to the deaths of over 75 million people worldwide in the 14th century, may have other nasty tricks. Yersinia pestis can normally be treated and cured with a course of antibiotics, if caught within a few days of the symptoms.

11 Sep 2008

Nicolas Sarkozy launches international malaria campaign

French President Nicolas Sarkozy on Tuesday launched an international malaria campaign during the opening of a photo exhibit on the disease in Paris, Panapress/Afriquenligne reports.

11 Sep 2008

Irish Times examines HIV/AIDS efforts in Moldovan region

The Irish Times on Tuesday examined the efforts of a Medecins Sans Frontieres mission in Transdniestria -- an enclave in Moldova that supports Russia and declared its independence from Moldova in 1990 -- to improve its health care system and implement an HIV/AIDS center in light of the region's high prevalence of the disease, which is four times that of the national average

11 Sep 2008