Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

MicroRNAs circulating in blood could lead to first diagnostic test for asthma

People with asthma have telltale molecules circulating in their blood, say researchers at Penn State College of Medicine. The discovery could lead to the first diagnostic blood test for asthma, as well as more targeted treatments for the condition.

16 Apr 2016

High dosages of antihistamines have dulling effect on genes associated with post-exercise recovery

After vigorous exercise, some 3,000 genes go to work to aid recovery by boosting muscles and blood vessels, but in the presence of high doses of antihistamines almost 27 percent of the gene response is blunted, according to University of Oregon researchers.

15 Apr 2016

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

In a new study, a research team at Basel University Hospital in Switzerland investigates the biochemical and physiological characteristics of orbicularis oculi, a group of facial muscles that control the eyelids and are selectively spared or involved in different neuromuscular disorders. What they found also helps to explain why another set of muscles—the extraocular muscles that control the movement of the eye—are not affected by Duchenne muscular dystrophy, congenital muscular dystrophy, and aging.

12 Apr 2016

Advances in NMR metabolomics: an interview with Professor Tone F. Bathen

The main objective of our research is to improve and individualize cancer diagnostics and cancer treatment. We try to achieve this through the integrated use of MR technology and the development of data-driven tools to analyze tumors on both a functional and molecular level.

From Bruker BioSpin Division 11 Apr 2016

Clinical study shows association between Corus CAD blood test scores and cardiovascular event rates

CardioDx, Inc., a molecular diagnostics company specializing in cardiovascular genomics, announced today results from a genomic substudy of the NHLBI-funded Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial in nondiabetic patients receiving the Corus CAD blood test.

7 Apr 2016

Maternal smoking influences epigenetic programming of unborn child's genetic make-up

If mothers smoke during pregnancy, they influence the epigenetic programming of their unborn child's genetic make-up in the long term. This may give rise to an increased risk of the development of disease risks later in the child's life.

5 Apr 2016

Daily walnut consumption positively impacts blood cholesterol levels in older adults

Initial findings from the Walnuts and Healthy Aging study presented at Experimental Biology 2016 (EB) indicate that daily walnut consumption positively impacts blood cholesterol levels without adverse effects on body weight among older adults.

4 Apr 2016

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that a microRNA called miR-181a dampens signals from the cancer-driving NFκB protein pathway in the most aggressive large B-cell lymphomas (DLBCL). By reducing NFκB signaling, miR-181a controls tumor cell proliferation and survival and could be the target of novel therapies. The study was published in the journal Blood.

2 Apr 2016

Experimental urine test identifies 92% of men with elevated PSA levels

An experimental urine test that detects genetic changes associated with prostate cancer identified 92 percent of men with elevated PSA (prostate-specific antigen) levels who had high-grade cancers, according to a study published today in JAMA Oncology online.

1 Apr 2016

Commonly used fungicides could cause gene expression changes in brain cells

Scientists at the UNC School of Medicine have found a class of commonly used fungicides that produce gene expression changes similar to those in people with autism and neurodegenerative conditions, including Alzheimer's disease and Huntington's disease.

31 Mar 2016

Penn researchers discover molecular mechanism that underlies common cerebrovascular disease

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures, yet exactly how they form is somewhat of a mystery. Now, a team from the Perelman School of Medicine at the University of Pennsylvania has discovered the molecular mechanism that underlies this common cerebrovascular disease. They published their results this week online ahead of print in Nature.

31 Mar 2016

Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

A novel mouse model of a highly lethal form of acute myeloid leukemia (AML) offers a new tool for scientists working to better understand this disease and research new therapeutic targets.

31 Mar 2016

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

While childhood cancer is rare (adult malignancies after 20 years are 20-30 times more common in general) it remains a major cause of death by disease in children. 15,700 children are diagnosed with cancer each year in the USA.

31 Mar 2016

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?

29 Mar 2016

Shugoshin protein maintains proper gene expression in subtelomeres

A research group discovered a new function of the chromosomal terminus, which may lead to the clarification of the mechanism for developing abnormal telomere structure such as multiple malformation and mental retardation.

29 Mar 2016

Novel way of hitting prostate cancer

Researchers at UC Davis, in collaboration with the other institutions, have found that suppressing the nuclear receptor protein ROR-γ with small-molecule compounds can reduce androgen receptor (AR) levels in castration-resistant prostate cancer and stop tumor growth.

29 Mar 2016

Gleevec could be novel therapeutic agent for type 2 diabetes

The cancer treatment drug Imatinib, otherwise known as Gleevec is approved to treat various forms of cancer, mostly notably chronic myeloid leukemia (CML). However, researchers have stumbled onto another possible use for it, curing type 2 diabetes.

28 Mar 2016

BIDMC investigators identify precise 5-gene classifier for discriminating early pancreatic cancer

Pancreatic cancer, the fourth leading cause of cancer death in the United States, is often diagnosed at a late stage, when curative treatment is no longer possible. A team led by investigators at Beth Israel Deaconess Medical Center has now identified and validated an accurate 5-gene classifier for discriminating early pancreatic cancer from non-malignant tissue.

28 Mar 2016

Study identifies genetic differences in kidney tumors of African-Americans

A University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared with whites.

26 Mar 2016

UC Berkeley biologists discover potential target for unisex contraceptives

UC Berkeley biologists have discovered the switch that triggers the power kick sperm use to penetrate and fertilize a human egg, uncovering a possible source of male infertility but also a potential target for contraceptives that work in both men and women.

26 Mar 2016

Gene Expression News and Research

Further Reading

MicroRNAs circulating in blood could lead to first diagnostic test for asthma

High dosages of antihistamines have dulling effect on genes associated with post-exercise recovery

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

Advances in NMR metabolomics: an interview with Professor Tone F. Bathen

Clinical study shows association between Corus CAD blood test scores and cardiovascular event rates

Maternal smoking influences epigenetic programming of unborn child's genetic make-up

Daily walnut consumption positively impacts blood cholesterol levels in older adults

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

Experimental urine test identifies 92% of men with elevated PSA levels

Commonly used fungicides could cause gene expression changes in brain cells

Penn researchers discover molecular mechanism that underlies common cerebrovascular disease

Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

Shugoshin protein maintains proper gene expression in subtelomeres

Novel way of hitting prostate cancer

Gleevec could be novel therapeutic agent for type 2 diabetes

BIDMC investigators identify precise 5-gene classifier for discriminating early pancreatic cancer

Study identifies genetic differences in kidney tumors of African-Americans

UC Berkeley biologists discover potential target for unisex contraceptives

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy