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Monocyte signature predicts dexamethasone response in severe COVID-19 patients

Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy.

3 Jul 2024

Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

Beyond PMS: A poorly understood disorder means periods of despair for some women

For the most part, Cori Lint was happy. She worked days as a software engineer and nights as a part-time cellist, filling her free hours with inline skating and gardening and long talks with friends.

3 Jul 2024

Digital screening for depression: Does automated feedback help?

The efficacy of two versions of automated feedback following internet-based depression screening on the severity of depression.

3 Jul 2024

New hope for solid tumors with enhanced CAR-T cells

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

3 Jul 2024

New HIV test targets neglected strains in global cure hunt

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa - a vital tool in the search for an HIV cure that will benefit patients around the world.

3 Jul 2024

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading.

2 Jul 2024

Study links vegetable protein to delayed puberty through gut microbiome changes

A large Chinese study found that high vegetable protein intake is linked to later puberty timing and beneficial gut microbiome changes in children, while high animal protein intake is associated with earlier puberty. The gut microbiome mediates these effects.

2 Jul 2024

TRPC5 gene identified as a diagnostic marker of obesity and postpartum depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

2 Jul 2024

Advancements in immunotherapy for hepatocellular carcinoma offer hope to patients

Hepatocellular carcinoma (HCC) is a primary liver cancer predominantly arising from chronic liver diseases such as hepatitis B and C infections, alcohol abuse, and metabolic disorders.

2 Jul 2024

Using dark-field X-ray imaging to diagnose kidney stones

The best way to treat kidney stones depends on how what they are composed of and how they are shaped.

2 Jul 2024

Financial incentives can improve smoking cessation among socioeconomically disadvantaged adults

A study published today by a University of Oklahoma researcher shows that financial incentives can make a big difference in helping smokers quit.

2 Jul 2024

WHO recommends a comprehensive set of tobacco cessation interventions

The World Health Organization (WHO) recommends a comprehensive set of tobacco cessation interventions, including behavioral support delivered by health-care providers, digital cessation interventions and pharmacological treatments in a first guideline on tobacco cessation.

2 Jul 2024

Pharmacogenomics: A pathway to personalized treatment in prostate cancer

Prostate cancer (PC) stands as the second leading cause of death among American men, with about 1 in 8 men diagnosed during their lifetime.

2 Jul 2024

Study hints at a promising approach for treating wet age-related macular degeneration

A new study in mice hints at the promise of an eventual alternative treatment option for the "wet" version of age-related macular degeneration (AMD).

2 Jul 2024

Cellular Origins acquires Actia Platform IP to enhance automated cell therapy manufacturing

Cellular Origins, a TTP Company, focused on enabling scalable, cost-effective, and efficient manufacture of cell and gene therapies (CGTs), today announced the acquisition of the ACTIA (Autologous Cell Therapy Industrial Automation) Platform IP, developed by Geoff Hodge whilst CEO of SOTIO Biotech US. The ACTIA Platform complements Cellular Origins’ existing approach and will accelerate and expand R&D efforts to further develop the Company’s robotic solution for automated cell therapy manufacturing, Constellation™.

From Cellular Origins 2 Jul 2024