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Researchers find key mechanism of cell damage in aging and disease

Researchers have taken a first snapshot of how a class of highly reactive molecules inflicts cellular damage as part of aging, heart disease, stroke, cancer, diabetes, kidney disease and Alzheimer's disease to name a few. According to a study published today in the journal Cell, researchers have discovered a tool that can monitor related damage and determine the degree to which antioxidant drugs effectively combat disease.

24 Jul 2008

Raltegravir drug combo works against highly resistant strain of HIV

A study involving an international team of scientists has discovered that a new drug when combined with other anti-HIV medications, is particularly effective against a highly resistant strain of the HIV virus.

24 Jul 2008

Washington Post examines HIV/AIDS among Hispanics in U.S.

HIV/AIDS among the Hispanic community in the U.S. is reaching what some public health experts are calling a "simmering public health crisis," the Washington Post reports.

24 Jul 2008

Statins appear to improve survival in kidney transplant recipients

For patients receiving kidney transplants, treatment with cholesterol-lowering "statin" drugs may lead to longer survival, reports a study in the November 2008 Journal of the American Society of Nephrology (JASN).

23 Jul 2008

New technique measures formation of clumps of proteins in protein-based pharmaceuticals

Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals.

23 Jul 2008

Researchers identify compound in human saliva that greatly speeds wound healing

A report by scientists from The Netherlands published online in The FASEB Journal identifies a compound in human saliva that greatly speeds wound healing.

23 Jul 2008

Open access to large-scale drug discovery data

The Wellcome Trust has awarded £4.7 million (€5.8 million) to EMBL's European Bioinformatics Institute (EMBL-EBI) to support the transfer of a large collection of information on the properties and activities of drugs and a large set of drug-like small molecules from publicly listed company Galapagos NV to the public domain.

23 Jul 2008

Antiretroviral treatment programs should take poverty, hunger into account, report says

Programs that provide access to no-cost antiretroviral drugs have had a significant impact on people living with HIV/AIDS, but they also should take into account the effects of poverty and hunger, according to a report recently released by the Catholic Agency for Overseas Development, PlusNews reports.

23 Jul 2008

Widespread adoption of e-prescribing could save U.S. $156 million over five years

HHS Secretary Mike Leavitt on Monday discussed the details of an electronic prescribing incentive program scheduled to begin on Jan. 1, 2009, that will increase Medicare payments to physicians who adopt the technology, the AP/Chicago Tribune reports.

23 Jul 2008

CMS proposal would limit industry practice that raises costs for some Medicare drug plan beneficiaries

A CMS proposal under consideration would limit a practice used by pharmacy benefit managers known as "lock-in pricing" that can increase costs for beneficiaries enrolled in the Medicare drug benefit and bring them into the so-called "doughnut hole" coverage gap more quickly, the Wall Street Journal reports.

23 Jul 2008

Alaska Group to offer health coverage to employees of not-for-profit

The Foraker Group, an organization that supports not-for-profit organizations in Alaska, on Thursday announced that it will offer health insurance to employees of private, not-for-profit organizations in the state, the Anchorage Daily News reports.

23 Jul 2008

Bioscience fund GBS invests US$6m in Xenome

Biopharmaceutical company Xenome Limited today announced it has received a convertible note placement of US$6 million from GBS Venture Partners, a Melbourne based life sciences specialist that invests in unlisted and listed high growth companies involved in innovative technologies.

23 Jul 2008

Roche starts acquisition process of ARIUS - fast tracks access to screening platform for antibody therapeutics

Roche and ARIUS Research Inc. have announced that the two companies have signed a definitive agreement for Roche to acquire ARIUS in an all-cash transaction at a price of approximately C$191 million.

23 Jul 2008

New study finds working age adults with major chronic conditions grew 25 percent over 10 years

As the number of working-age adults who have major chronic conditions grew between 1997 and 2006, those without health coverage in this group experienced substantial erosion in access to health care, according to a new study by Kaiser Family Foundation researchers published today as a Health Affairs Web Exclusive.

22 Jul 2008

PBS' 'News Hour' examines efforts of Baylor's Pediatric AIDS Corps to fight HIV/AIDS in Africa

PBS' "News Hour with Jim Lehrer" on Thursday examined efforts from the Baylor College of Medicine's Pediatric AIDS Corps to fight HIV/AIDS among children in Malawi.

22 Jul 2008

West Virginia prescription drug program showing growth, success within first three months

West Virginia Rx, a new state-managed prescription drug program that allows uninsured state residents to obtain medications at no cost, is on track to enroll 10,000 people within its first year, the Charleston Gazette reports (Kabler, Charleston Gazette, 7/17).

22 Jul 2008

Discovery of cells for spinal-cord repair

A researcher at MIT's Picower Institute for Learning and Memory has pinpointed stem cells within the spinal cord that, if persuaded to differentiate into more healing cells and fewer scarring cells following an injury, may lead to a new, non-surgical treatment for debilitating spinal-cord injuries.

22 Jul 2008

Epilepsy drug may raise the risk of birth defects

Scientists have found that women who take an epilepsy drug while they are pregnant may increase the risk of birth defects in their babies.

22 Jul 2008

Suspect protein HMGB1 found to promote DNA repair, prevent cancer

An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academies of Science.

21 Jul 2008

Taking the epilepsy drug topiramate may increase risk of birth defects

Taking the epilepsy drug topiramate alone or along with other epilepsy drugs during pregnancy may increase the risk of birth defects, according to a study published in the July 22, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

21 Jul 2008

Drugs News and Research

Researchers find key mechanism of cell damage in aging and disease

Raltegravir drug combo works against highly resistant strain of HIV

Washington Post examines HIV/AIDS among Hispanics in U.S.

Statins appear to improve survival in kidney transplant recipients

New technique measures formation of clumps of proteins in protein-based pharmaceuticals

Researchers identify compound in human saliva that greatly speeds wound healing

Open access to large-scale drug discovery data

Antiretroviral treatment programs should take poverty, hunger into account, report says

Widespread adoption of e-prescribing could save U.S. $156 million over five years

CMS proposal would limit industry practice that raises costs for some Medicare drug plan beneficiaries

Alaska Group to offer health coverage to employees of not-for-profit

Bioscience fund GBS invests US$6m in Xenome

Roche starts acquisition process of ARIUS - fast tracks access to screening platform for antibody therapeutics

New study finds working age adults with major chronic conditions grew 25 percent over 10 years

PBS' 'News Hour' examines efforts of Baylor's Pediatric AIDS Corps to fight HIV/AIDS in Africa

West Virginia prescription drug program showing growth, success within first three months

Discovery of cells for spinal-cord repair

Epilepsy drug may raise the risk of birth defects

Suspect protein HMGB1 found to promote DNA repair, prevent cancer

Taking the epilepsy drug topiramate may increase risk of birth defects

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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