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Blocking Hutchinson-Gilford progeria syndrome (HGPS) with anticancer drugs

A class of anticancer drugs currently being evaluated in phase 3 clinical trials may also be an effective treatment for Hutchinson-Gilford progeria syndrome (HGPS), a fatal genetic disorder that causes premature aging.

29 Aug 2005

Drugs known as farnesyltransferase inhibitors (FTIs) may hold promise for premature aging disorder

In a surprising development, a research team led by the National Human Genome Research Institute (NHGRI), has found that a class of experimental anti-cancer drugs also shows promise in laboratory studies for treating a fatal genetic disorder that causes premature aging.

29 Aug 2005

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

A close structural relative of the celebrated COX-2 inhibitor celecoxib (brand name: Celebrex) is a potent tumor fighter, able to wipe out tumor cells that are resistant to conventional chemotherapies, according to an interdisciplinary team of researchers from the University of Southern California.

29 Aug 2005

First genetic evidence that protein synthesis is critical for the regulation of memory formation

A group of Montreal researchers has discovered that GCN2, a protein in cells that inhibits the conversion of new information into long-term memory, may be a master regulator of the switch from short-term to long-term memory.

29 Aug 2005

Depressant benzodiazepine especially effective at treating seizure in alcohol withdrawal syndrome patients

Tranquilizers work better than placebos at treating the symptoms of alcohol withdrawal syndrome but they may not work better than other drugs, according to a new review of recent studies.

29 Aug 2005

New laboratory method for quickly detecting active anthrax proteins

A new laboratory method for quickly detecting active anthrax proteins within an infected blood sample at extremely low levels has been developed by researchers at the National Institute of Standards and Technology (NIST), the U.S. Army Medical Research Institute of Infectious Diseases and the National Cancer Institute.

29 Aug 2005

Molecular missing link between fasting and acute attacks of porphyria

A team of researchers has discovered a molecular missing link that helps explain why fasting brings on acute attacks of the genetic disease hepatic porphyria, according to a new report in the 26 August issue of the journal Cell.

29 Aug 2005

Leading medical journal says homeopathy no better than dummy drugs

Leading medical journal The Lancet has rubbished homeopathy and says it is no more value than dummy drugs.

29 Aug 2005

Supermolecules strike blow to cancer cells

Chemistry and biology researchers at Virginia Tech have enhanced the abilities of the molecules they are creating to deliver killing blows to cancer cells. The man-made molecular complexes enter cancer cells and, when signaled, deliver killing medicine or cause the cell to change.

29 Aug 2005

Minimally invasive prostate removal aided by a robot has possible benefits, high cost

Although minimally invasive prostate removal aided by a robot can lead to less blood loss, shorter hospital stays and fewer complications, there is no evidence that the procedure improves cure rates, according to a new technology assessment.

29 Aug 2005

Study reveals functional link between emotion processing centers in the brain and certain physiological processes relevant to disease

The mere mention of a stressful word like "wheeze" can activate two brain regions in asthmatics during an attack, and this brain activity may be associated with more severe asthma symptoms, according to a study by University of Wisconsin-Madison researchers and collaborators.

29 Aug 2005

New vaccine protects more effectively against tuberculosis

Max Planck researchers have uncovered the mechanism by which the new genetically engineered tuberculosis vaccine functions.

28 Aug 2005

Neurotransmitter orexin influences reward processing - associated with pleasure and reward pathways in the brain

Researchers at the University of Pennsylvania School of Medicine have discovered that the recently identified neurotransmitter orexin (also known as hypocretin) influences reward processing by activating neurons in the lateral hypothalamus region of the brain.

28 Aug 2005

Compound might defeat African sleeping

One of the most devastating diseases in sub-Saharan Africa almost disappeared in the late 1950s.

26 Aug 2005

Ichor Medical Systems issued key patent

Ichor Medical Systems today announced that it has been issued a patent that protects vital elements of the company's technology.

25 Aug 2005

Protein snapin has potential as a drug target in therapies aimed at learning and memory disorders

Rutgers' Bonnie Firestein likens nerve cells to trees -- some are short and bushy with many branches while others are tall with a few branches coming out of one or two main trunks. Different branching patterns correlate with specific disorders and Firestein's quest is to discover how these dissimilar patterns come about and why.

25 Aug 2005

Experimental immunusuppressant drug preserves transplanted kidneys

An international team of transplant physicians has shown that the investigational drug belatacept (LEA29Y) preserves transplanted kidney function as effectively as cyclosporine, the drug most commonly used to prevent the immune system from rejecting transplanted organs.

24 Aug 2005

Drugs News and Research

Blocking Hutchinson-Gilford progeria syndrome (HGPS) with anticancer drugs

Drugs known as farnesyltransferase inhibitors (FTIs) may hold promise for premature aging disorder

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

First genetic evidence that protein synthesis is critical for the regulation of memory formation

Depressant benzodiazepine especially effective at treating seizure in alcohol withdrawal syndrome patients

New laboratory method for quickly detecting active anthrax proteins

Molecular missing link between fasting and acute attacks of porphyria

Leading medical journal says homeopathy no better than dummy drugs

Supermolecules strike blow to cancer cells

Minimally invasive prostate removal aided by a robot has possible benefits, high cost

Study reveals functional link between emotion processing centers in the brain and certain physiological processes relevant to disease

New vaccine protects more effectively against tuberculosis

Neurotransmitter orexin influences reward processing - associated with pleasure and reward pathways in the brain

Compound might defeat African sleeping

Ichor Medical Systems issued key patent

Protein snapin has potential as a drug target in therapies aimed at learning and memory disorders

Experimental immunusuppressant drug preserves transplanted kidneys

Drug company donates bird flu vaccine to World Health Organization

Prince Charles champions alternative healthcare

New drug that selectively blocks immune responses protects kidneys after transplant

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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