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6 in every 100 patients die in hospital due to adverse drug reaction

Six of every 100 patients who die in hospital do so as a consequence of an adverse drug reaction or, in other words, a fatal reaction to medicines. Those are the conclusions of a research carried out at the Department of Medicine of the University of Granada, in collaboration with the Clinical Hospital San Cecilio of Granada, by Alfredo Jose Pardo Cabello and directed by Professors Emilio Puche Canas (Department of Pharmacology) and Francisco Javier Gomez Jimenez (Department of Medicine).

6 Jul 2008

Researchers solve structure of proteins known as sodium glucose co-transporters

Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells.

4 Jul 2008

California pharmacies expect disaster after Loss in lawsuit loss to stop 10% Medi-Cal provider cuts

Today, a state court denied eight retail pharmacies' motion to stop the ten percent Medi-Cal provider cuts. The pharmacies sought a temporary restraining order (TRO) from Sacramento Superior Court against the California Department of Health Care Services and its director Sandra Shewry to block the cuts from being implemented.

4 Jul 2008

GlaxoSmithKline, Novartis found guilty of overcharging Alabama Medicaid Program

An Alabama state court jury on Tuesday found pharmaceutical companies GlaxoSmithKline and Novartis guilty of defrauding the state Medicaid program by charging artificially high prices for medications and ordered the two companies to pay more than $114 million in restitution, the AP/Minneapolis Star Tribune reports.

4 Jul 2008

New target for the potential treatment of tuberculosis

Scientists have uncovered a new target for the potential treatment of tuberculosis (TB), finally resolving a long-running debate about how the bacterial cell wall is built.

3 Jul 2008

Cases of malaria increasing in UK

A huge rise in the numbers of UK residents travelling to malaria endemic areas, combined with a failure to use prevention measures, has significantly increased cases of imported falciparum malaria in the UK over the past 20 years, according to a study published on BMJ.com.

3 Jul 2008

Funding boost in fight against leukaemia

University of Manchester researchers have been awarded £1.6 million to study a group of genes identified as playing a key role in leukaemia.

From The University of Manchester 3 Jul 2008

Statins have unexpected effect on pool of powerful brain cells

Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.

3 Jul 2008

Study examines death rates for people newly diagnosed with HIV

In the five years after their diagnosis, people living with HIV in developed countries and receiving highly active antiretroviral therapy are no more likely to die than HIV-negative people, according to a study published Tuesday in the Journal of the American Medical Association, Reuters reports (Kahn, Reuters, 7/1).

3 Jul 2008

WHO, Stop TB Partnership, UNITAID announce new tuberculosis test that quickly diagnoses MDR-TB

The World Health Organization, Stop TB Partnership, UNITAID and the Foundation for Innovative New Diagnostics on Monday announced a joint project to distribute a new diagnostic test for multi-drug resistant tuberculosis that can produce results in two days instead of the standard two or three months, the New York Times reports. Difficulty in identifying MDR-TB has been a "major obstacle" in controlling TB because many patients die or spread the disease while waiting for test results, the Times reports.

3 Jul 2008

Microchip-based device determines the genetic signature of lung tumors

Massachusetts General Hospital (MGH) investigators have shown that an MGH-developed, microchip-based device that detects and analyzes tumor cells in the bloodstream can be used to determine the genetic signature of lung tumors, allowing identification of those appropriate for targeted treatment and monitoring genetic changes that occur during therapy. A pilot study of the device called the CTC-chip will appear in the July 24 New England Journal of Medicine and is receiving early online release.

3 Jul 2008

Computational research hones cancer-fighting strategies

A Florida State University faculty member who uses computational techniques to evaluate a new class of cancer-killing drugs is attracting worldwide attention from other researchers.

3 Jul 2008

New insight into role of statins in dementia

3 Jul 2008

Genetic link between Crohn's and asthma discovered

Research into the genetic causes of Crohn's disease has revealed that the gene ORMDL3, known to be a risk factor for childhood asthma, is also associated with Crohn's disease, and in the process links between the condition and other diseases have been found.

2 Jul 2008

Discovery of new drug candidates to combat bird flu

As the specter of a worldwide outbreak of avian or "bird flu" lingers, health officials recognize that new drugs are desperately needed since some strains of the virus already have developed resistance to the current roster of anti-flu remedies.

2 Jul 2008

Body's own 'marijuana' is good for the skin

Scientists from Hungary, Germany and the U.K. have discovered that our own body not only makes chemical compounds similar to the active ingredient in marijuana (THC), but these play an important part in maintaining healthy skin

2 Jul 2008

Brain trick offers treatment hope for Alzheimer's

Scientists in the UK and Canada have made a significant step forward in the search for new drugs to treat Alzheimer's disease.

2 Jul 2008

Artichoke leaf extract shown to lower cholesterol

Researchers at the University of Reading have found that an over-the-counter Artichoke Leaf Extract (ALE) from the globe artichoke plant can lower cholesterol in otherwise healthy individuals with moderately raised levels.

2 Jul 2008

FDA food protection plan shows improvements

The U.S. Food and Drug Administration's Food Protection Plan Progress Report, released today in conjunction with the Interagency Working Group on Import Safety Action Plan Update, shows significant areas of activity to further improve the safety of America's food supply since unveiling its Food Protection Plan in November 2007.

2 Jul 2008

Pharmaceutical companies say new approach by FDA has led to decrease approvals of new medications

An "intensifying focus on safety and a diminished tolerance for side effects" by FDA have "dramatically lowered" the chances that experimental medications will reach the market and have led to a recent decrease in approvals of new treatments, according to pharmaceutical companies, the Wall Street Journal reports.

2 Jul 2008