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Key step in the production of beta-amyloid

Researchers at UT Southwestern Medical Center have defined a key step in the production of beta-amyloid, a short protein that is thought to be responsible for the development of Alzheimer's disease. Understanding this step may aid in the discovery of drugs that could help block the disease from developing.

11 Aug 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

Introgen announces additional broad patent in China

Introgen Therapeutics has announced that a patent with broad claims directed to combination therapy with the p53 gene and conventional chemotherapy or radiation was issued in China.

11 Aug 2005

Pig brain cell transplant looks hopeful for treating Huntington's disease

According to researchers at Australian bioscience company Living Cell Technologies (LCT), if approved, pig brain cells wrapped in a seaweed derivative could be implanted into human brains by sometime next year to treat Huntington's disease.

11 Aug 2005

Taking parathyroid hormone followed by a year on alendronate shows strong osteoporosis benefit

Postmenopausal women who took a bone-building drug for one year followed by a year on a standard drug that fights bone loss experienced greater increases in bone density than has been reported from any other drug regimen, an NIH-sponsored study has found. Bone density is the standard predictor of fracture risk associated with osteoporosis.

11 Aug 2005

Cancer causing potential of the sex hormones

The cancer causing potential of the sex hormones used in hormone therapy has been known since the 1930s, say researchers and women's health advocates in the Journal of Epidemiology and Community Health.

11 Aug 2005

FDA approval sought for Pfizer's new cancer drug

Drug company Pfizer has announced it has submitted a New Drug Application (NDA) for its cancer drug Sutent, to the U.S. Food and Drug Administration (FDA).

11 Aug 2005

Seniors in U.S. can relax as official says Medicare drug benefit scheme will cost less

Federal officials have said that Medicare's controversial new drug benefit for seniors, may in fact cost less than first projected, because of the very competitive bids from insurers and other providers.

10 Aug 2005

Blondes may have fun but redheads can take the pain

According to a new British study, blondes may have more fun, but redheads are less likely to feel the pain.

10 Aug 2005

Four out of five prisoners test positive for drugs

In a shocking revelation it appears that a third of prisoners in Scottish jails are using drugs at the time of their release.

10 Aug 2005

Important breast cancer discovery

Scientists at the McGill University Health Centre (MUHC) have made an important discovery that will advance our understanding of how the female hormone estrogen causes growth of breast cancer cells. The research, in collaboration with scientists at the Institut de Recherches Cliniques de Montreal (IRCM) identifies 153 genes that respond to estrogen and one in particular that can be used to halt the growth of breast cancer cells.

10 Aug 2005

Quality of the doctor-patient relationship can greatly affect patients' medication use

Patients who trust their doctors are more likely to stick to their prescription medicines, even if they face high out-of-pocket costs, a new study finds. But patients who have lower levels of trust in their physicians, or who have depression-like symptoms, are much more likely to skip doses or refills when costs become a problem for them.

10 Aug 2005

Current clinical practice guidelines are not written with older adults with multiple illnesses in mind

The aging of the population and the increasing prevalence of chronic diseases pose challenges to the development and application of clinical practice guidelines (CPGs), according to background information in the article. In 1999, 48 percent of Medicare beneficiaries aged 65 years or older had at least 3 chronic medical conditions and 21 percent had 5 or more.

10 Aug 2005

Firefly protein lets researchers monitor molecule known as IKK (for IKappa kinase) linked to cancer

Scientists have used a glowing protein from fireflies to observe the activity of a molecule that is an important target for new drugs to treat cancer, autoimmune diseases and several other disorders.

9 Aug 2005

Researchers identify protein called EMP-1 that is present in the tumors of patients who fail to respond to treatment with gefitinib

By the time the human genome was mapped, cancer researchers had already begun investigating the proteins that were encoded by these newly identified genes.

9 Aug 2005

Over-supply of blood sugar could be a major cause of erectile dysfunction in diabetic men

Researchers have found that one particular simple sugar, present in increased levels in diabetics, interferes with the chain of events needed to achieve and maintain erection and can lead to permanent penile impairment over time.

9 Aug 2005

Scientists enhance the anti-cancer properties of a digitalis, a drug commonly used to treat heart disease

Employing a simple new technique to manipulate the sugars that power many front-line drugs, a team of Wisconsin scientists has enhanced the antic-cancer properties of a digitalis, a drug commonly used to treat heart disease.

9 Aug 2005

U.S. drug makers up in arms over info on FDA "Drug Watch" web page

Pharmaceutical companies in the United States are up in arms over plans by U.S. regulators to release preliminary information, about the potential side effects of drugs.

9 Aug 2005

Testing for the activity of certain genes can predict response to chemotherapy for breast cancer

Breast cancer patients could find out whether they will respond positively to chemotherapy treatment by testing for the activity of certain genes.

9 Aug 2005

DDT resistance in flies carries no cost

For those concerned with the troublesome effects of genetic resistance to drugs and pesticides, the conventional wisdom of evolution offers a reassuring word: In the absence of the original chemical threat, most resistance mutations would cause a disadvantage to their hosts and might be expected to quickly leave the genetic landscape once the use of a drug or insecticide is suspended or withdrawn.

9 Aug 2005

Drugs News and Research

Key step in the production of beta-amyloid

Researchers find drug targets for treating metabolic syndrome

Introgen announces additional broad patent in China

Pig brain cell transplant looks hopeful for treating Huntington's disease

Taking parathyroid hormone followed by a year on alendronate shows strong osteoporosis benefit

Cancer causing potential of the sex hormones

FDA approval sought for Pfizer's new cancer drug

Seniors in U.S. can relax as official says Medicare drug benefit scheme will cost less

Blondes may have fun but redheads can take the pain

Four out of five prisoners test positive for drugs

Important breast cancer discovery

Quality of the doctor-patient relationship can greatly affect patients' medication use

Current clinical practice guidelines are not written with older adults with multiple illnesses in mind

Firefly protein lets researchers monitor molecule known as IKK (for IKappa kinase) linked to cancer

Researchers identify protein called EMP-1 that is present in the tumors of patients who fail to respond to treatment with gefitinib

Over-supply of blood sugar could be a major cause of erectile dysfunction in diabetic men

Scientists enhance the anti-cancer properties of a digitalis, a drug commonly used to treat heart disease

U.S. drug makers up in arms over info on FDA "Drug Watch" web page

Testing for the activity of certain genes can predict response to chemotherapy for breast cancer

DDT resistance in flies carries no cost

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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