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Scientist have found an unexpected effect of the interaction of PTEN and p53 genes in early stage prostate cancer

Prostate cancer, the second leading cause of cancer death for men in the United States, is caused by changes in several tummor suppressor genes including PTEN and p53. Up to 70 percent of men with prostate cancer have lost one copy of the PTEN gene at the time of diagnosis, and p53 is absent in a high number of patients with advanced prostate cancer.

3 Aug 2005

Pfizer adds warning to Celebrex arthritis drug

Pharmaceutical giant Pfizer has adapted the label of its Celebrex arthritis drug and added a prominent warning of possible cardiovascular risks, such as increased risk of heart attacks.

3 Aug 2005

Not enough women take part in heart drug trials

Scientists say because women are under-represented in the clinical trials of heart drugs, doctors are left in the dark as to how treatments may work differently in their bodies.

3 Aug 2005

First evidence that complex genetic interactions account for autism risk

Using a novel analysis of the interactions among related genes, Duke University Medical Center researchers have uncovered some of the first evidence that complex genetic interactions account for autism risk. The Duke team found that the brain mechanism that normally stops or slows nerve impulses contributes to the disease.

3 Aug 2005

Breed and placement affect skin drug delivery

Skin creams and patches might be the easiest way to give your pets medicine but their success also depends on the breed and where it’s applied.

2 Aug 2005

Drug use among Indiana youth sees biggest drop in years

A new report on alcohol, tobacco and other drug use by the Indiana Prevention Resource Center at Indiana University Bloomington demonstrates a significant downward trend in youth drug use and includes the agency's first compilation of data concerning methamphetamine use and gambling by sixth- through 12th-grade students.

2 Aug 2005

HAART reduces AIDS rates by 86%

Highly active antiretroviral therapy (HAART) for HIV-infected individuals has reduced the rate of progression to AIDS or death by 86%, according to new research from Bristol University published in The Lancet.

2 Aug 2005

Medicare at 40: Past Accomplishments and Future Challenges

As Americans commemorate Medicare's 40th Anniversary, AARP's Public Policy Institute (PPI) has released the report, "Medicare at 40," which examines the program's successes as well as the challenges that lie ahead. It found that Medicare has largely accomplished its original goals of ensuring access to care and establishing financial protections for medical costs.

2 Aug 2005

Omega-6 fatty acids promote the growth of prostate tumor cells in the laboratory

A study conducted at the San Francisco VA Medical Center (SFVAMC) has demonstrated that omega-6 fatty acids such as the fat found in corn oil promote the growth of prostate tumor cells in the laboratory.

2 Aug 2005

Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease

Researchers investigating anecdotal evidence that cannabis relieves some of the symptoms of inflammatory bowel disease (IBD) have discovered a potential new target for cannabis-derived drugs for treatment of the disease.

2 Aug 2005

Drugs with similar chemical attributes as Ecstasy might offer useful alternatives to current therapies for Parkinson's disease

Amphetamines, including the drug popularly known as Ecstasy, can reverse the symptoms of Parkinson's disease in mice with an acute form of the condition, according to new research at Duke University Medical Center.

2 Aug 2005

Arf gene prevents excessive growth of blood vessels in the developing eye

A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital.

2 Aug 2005

Researchers characterize the proteome of the human cornea

In doing so, they have identified 141 distinct proteins, 99 of which had not been previously recognized in mammalian corneas. The details of their findings appear in the August/September issue of Molecular and Cellular Proteomics, an American Society for Biochemistry and Molecular Biology journal.

1 Aug 2005

Researchers have identified a pathway that is specific for cancer

When cancer spreads, people often die. That's why a lot of cancer research and drugs focus on the metabolic pathways that allow cancer to metastasize -- to spread from one part of the body to another.

1 Aug 2005

New recommendations can help medical arms of the military meet their mission

As reported last December in the New England Journal of Medicine, the U.S. military's on-the-ground surgical strategy now aims at "damage control, not definitive repair, unless it can be done quickly."

1 Aug 2005

Cannabis drugs may benefit those with bowel disease

UK scientists say they believe that patients with inflammatory bowel disease may benefit from cannabis-based drugs.

1 Aug 2005

Controlling the expression of genes by turning them on or off could produce a drug for the treatment or cure of almost any disease

A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center.

1 Aug 2005

Pseudomonas aeruginosa has broken the immune system's code

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

1 Aug 2005

People with HIV in developing countries do just as well on antiretroviral therapy (ART) programs as do people with HIV on ART programs in developed countries

It also shows that people with HIV who are given free ART drugs will do "significantly" better at fighting the disease compared to those who must pay for the drugs.

1 Aug 2005