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Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

A team of scientists from France has recently demonstrated photosensitive antiviral activity of the natural compound pheophorbide a (Pba) against a broad range of enveloped viruses, including coronaviruses.

12 Jul 2021

Real-world evidence SARS-CoV-2 mRNA vaccines work and help prevent worst outcomes

Researchers in the United States have conducted a study demonstrating the real-world effectiveness of the Pfizer-BioNTech BNT162b2 and Moderna mRNA-1273 vaccines at preventing hospitalizations due to coronavirus disease 2019 (COVID-19).

12 Jul 2021

Hematopoietic stem cells take advantage of 'junk' RNA to replenish the blood system

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients.

12 Jul 2021

Students at Lewis Katz School of Medicine stand to benefit from new $1 million NIGMS grant

Rapid evolution in the field of biomedical research demands well-trained scientists. Adapting biomedical research training programs to keep up with the increasingly complex and interdisciplinary nature of the field, however, presents complex challenges for higher-education institutions.

12 Jul 2021

The progressive increase in transmissibility and virulence of emerging SARS-CoV-2 variants could lead to a significantly more deadly pandemic

Researchers from Toronto University, Canada, recently showed that these emerging VOCs were linked to increased virulence, as determined by hospitalization risk, ICU admission, and mortality. This study is currently available on the medRxiv* preprint server.

12 Jul 2021

Researchers discover new genetic driver of autism and other developmental disorders

A research group including Kobe University's Professor TAKUMI Toru (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) and Assistant Professor TAMADA Kota, both of the Physiology Division in the Graduate School of Medicine, has revealed a causal gene (Necdin, NDN) in autism model mice that have the chromosomal abnormality called copy number variation.

9 Jul 2021

Mating can turn off a single gene for multiple generations, study shows

Evidence suggests that what happens in one generation--diet, toxin exposure, trauma, fear--can have lasting effects on future generations.

9 Jul 2021

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from Würzburg and Marburg reveals. The findings could help improve cancer therapies.

9 Jul 2021

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

While Delta (B.1.617.2) has overtaken Alpha (B.1.1.7) as the dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant in the United States, Alpha remained a force to be reckoned with in New York City earlier this year. New research published on the preprint medRxiv* server details breakthrough infections in vaccinated and unvaccinated individuals living in New York City.

9 Jul 2021

Researchers model probability of extinction of SARS-CoV-2 variant in an outbreak

However, it cannot be confirmed for certain that the strain has been eliminated, raising the question of how long a strain must go undetected before being considered, in all probability, extinct.

9 Jul 2021

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Researchers in the United States have conducted a study suggesting that individuals fully vaccinated against coronavirus disease 2019 (COVID-19) who develop breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are less likely to transmit the virus to others than unvaccinated infected individuals.

8 Jul 2021

Researchers uncover genetic markers associated with COVID-19 infection risk and severity

An international collaboration uncovers several genetic markers associated with SARS-CoV-2 infection and COVID-19 severity.

8 Jul 2021

New genomics workbook helps people use their family history to assess disease risks

Researchers at the National Human Genome Research Institute, part of the National Institutes of Health, have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.

8 Jul 2021

Study uncovers mutations in Polycomb group gene as underlying cause of novel neurological disorder

A multi-institutional study has discovered spontaneous mutations in RNF2 (RING2) gene as the underlying cause of a novel neurological disorder.

8 Jul 2021

Genetic analysis method reveals causal association between thyroid function and serum lipid metabolism

Thyroid hormones are amino acid-based molecules produced by the thyroid gland. Involved in direct or indirect regulation of key metabolic pathways, these molecules play critical roles in the development and normal functioning of the body.

8 Jul 2021

Do lockdowns exert selection pressure on overdispersion of SARS-CoV-2 variants?

New research recently released on the medRxiv* preprint server describes a mathematical model that has been developed to evaluate competitions between variants that differ in their level of overdispersion (k) and their mean infectiousness.

8 Jul 2021

How do host factors like the lung microbiome aid in SARS‐CoV‐2 infection?

A new article has been published in Cellular and Molecular Lifesciences, which focuses on the connection between host factors and the worsening of the COVID-19. Further, the impact of the virus on the host’s microbiome and secondary infection has also been studied.

8 Jul 2021

Researchers determine the structure of nanomachine essential for functioning of mTOR

The principle that form follows function does not only apply to design and architecture. It also applies to biology

8 Jul 2021

Optical genome mapping could change the existing workflow within cytogenetic laboratories

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately. Sometimes even better than all existing techniques together, as they describe in two proof-of-concept studies published in the American Journal of Human Genetics.

8 Jul 2021

How SARS-CoV-2 has evolved over the course of the pandemic

In an effort to understand the ongoing evolution of the SARS-CoV-2 genome, researchers constructed a phylogenetic tree of all available SARS-CoV-2 genomes.

7 Jul 2021

Genome News and Research

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

Real-world evidence SARS-CoV-2 mRNA vaccines work and help prevent worst outcomes

Hematopoietic stem cells take advantage of 'junk' RNA to replenish the blood system

Students at Lewis Katz School of Medicine stand to benefit from new $1 million NIGMS grant

The progressive increase in transmissibility and virulence of emerging SARS-CoV-2 variants could lead to a significantly more deadly pandemic

Researchers discover new genetic driver of autism and other developmental disorders

Mating can turn off a single gene for multiple generations, study shows

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

Researchers model probability of extinction of SARS-CoV-2 variant in an outbreak

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Researchers uncover genetic markers associated with COVID-19 infection risk and severity

New genomics workbook helps people use their family history to assess disease risks

Study uncovers mutations in Polycomb group gene as underlying cause of novel neurological disorder

Genetic analysis method reveals causal association between thyroid function and serum lipid metabolism

Do lockdowns exert selection pressure on overdispersion of SARS-CoV-2 variants?

How do host factors like the lung microbiome aid in SARS‐CoV‐2 infection?

Researchers determine the structure of nanomachine essential for functioning of mTOR

Optical genome mapping could change the existing workflow within cytogenetic laboratories

How SARS-CoV-2 has evolved over the course of the pandemic

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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