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Researchers trace gecko’s skin tumors to a gene implicated in deadly cancer

The leopard gecko's name was Mr. Frosty, and he was hard to miss. Yellow bands striped his back, and uncommonly white skin peeked out from speckles on his head and tail.

25 Jun 2021

Renowned scientists recover deleted SARS-CoV-2 data from Wuhan

Renowned evolutionary researcher, Jesse Bloom from the Fred Hutchinson Cancer Research Center, has conducted a phylogenetic analysis suggesting that the early severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequences that were obtained from the Huanan Seafood Market in Wuhan, China, are not fully representative of the viruses circulating in the city at the time of the coronavirus disease 2019 (COVID-19) outbreak.

24 Jun 2021

Researchers create first detailed atlas of the developing mouse brain

Researchers at Harvard University and the Broad Institute of MIT and Harvard have created a first detailed atlas of a critical region of the developing mouse brain, applying multiple advanced genomic technologies to the part of the cerebral cortex that is responsible for processing sensation from the body.

24 Jun 2021

Could polio vaccines induce cross-reactive antibodies that target SARS-CoV-2?

A new preprint released on the medRxiv* server explores a link between immunity to SARS-CoV-2, the earlier SARS-CoV, and childhood poliovirus vaccination. Almost 90% of the world’s people have received this vaccine, but antibodies elicited by it reduce over time and are almost absent at the end of adolescence.

24 Jun 2021

New tool can help conserve one of the UK’s most threatened mammals

A new tool to help conserve one of the UK’s most threatened mammals has been released today, with the publication of the first high-quality reference genome for the European water vole.

24 Jun 2021

Bivalent DNA SARS-CoV-2 vaccine induces strong humoral and cellular immunity in mice

A team of UK-based scientists has developed and validated a DNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that encodes both spike receptor-binding domain (RBD) and nucleocapsid of the virus as vaccine immunogens.

24 Jun 2021

Internal communication network in mammals provides new insights on obesity, skin disorders

National Institutes of Health scientists and their collaborators have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as obesity and inflammatory skin disorders develop. The new research is published in Cell.

24 Jun 2021

A study of circulating biomarkers in hospitalized patients infected with SARS-CoV-2 alpha variant

Now, a new study published on the medRxiv* preprint server proposes a rapid method to identify the mutations in B.1.1.7 (N501Y mutation and H69/V70 deletion) and the impact of this variant on various biomarkers in hospitalized patients. This is the first study that correlates the biomarker levels to SARS-CoV-2 variants.

23 Jun 2021

SARS-CoV-2 detection with a simple, inexpensive, and sensitive molecular test

Researchers from the US recently described a rapid molecular test named WHotLAMP for the detection of SARS-CoV-2 in saliva. WHotLAMP is easy to use, very sensitive at 3.6 viral RNA copies per microliter of saliva, specific, and inexpensive. This study is published on the medRxiv*preprint serve.

23 Jun 2021

Researchers unravel new mechanism that enables cancer development

Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new mechanism that activates specific genes, leading to the development of cancers.

23 Jun 2021

Heidelberg researchers replicate rare genetic defect in fish model

A rare genetic defect that affects the so-called ALG2 gene can cause serious metabolic diseases in humans. It does so through the defective formation of proteins and sugar molecules.

23 Jun 2021

Can antioxidants help manage neurological complications in COVID-19?

In a recent study published in Antioxidants, researchers evaluated the use of antioxidants as potential adjuvants for the treatment of COVID-19.

23 Jun 2021

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

A recent study published in Frontiers in Immunology focuses on the roles of the SADS-CoV N protein in IFN suppression during infection.

23 Jun 2021

Genome surveillance tool facilitates detection of COVID-19 variants

Swedish researchers have developed COVseq, a SARS-CoV-2 genome tracker that can be produced at a large scale for a small cost.

23 Jun 2021

Genetic risk score predicts onset and severity of scoliosis in adolescents

In a study published in the Journal of Bone and Mineral Research, investigators developed and validated a genetic risk score for predicting the onset and severity of the most common type of scoliosis in adolescents--called adolescent idiopathic scoliosis (AIS).

23 Jun 2021

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

The RDM Positive Impact Foundation is funding an ambitious $1.25 million research project at the UC Davis MIND Institute to study SYNGAP1.

22 Jun 2021

New human organoid mimics the earliest developmental steps of the nervous system in embryos

The progression from a round ball of cells to an embryo with a head and a tail is one of the most critical steps in an organism's development. But just how cells first start organizing themselves with directionality along this head-to-tail axis is hard to study because it happens in the earliest days of embryonic development, in the confines of a mammal's uterus.

22 Jun 2021

Genome News and Research

Researchers trace gecko’s skin tumors to a gene implicated in deadly cancer

Renowned scientists recover deleted SARS-CoV-2 data from Wuhan

Researchers create first detailed atlas of the developing mouse brain

Could polio vaccines induce cross-reactive antibodies that target SARS-CoV-2?

New tool can help conserve one of the UK’s most threatened mammals

Bivalent DNA SARS-CoV-2 vaccine induces strong humoral and cellular immunity in mice

Internal communication network in mammals provides new insights on obesity, skin disorders

A study of circulating biomarkers in hospitalized patients infected with SARS-CoV-2 alpha variant

SARS-CoV-2 detection with a simple, inexpensive, and sensitive molecular test

Researchers unravel new mechanism that enables cancer development

Heidelberg researchers replicate rare genetic defect in fish model

Can antioxidants help manage neurological complications in COVID-19?

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

Genome surveillance tool facilitates detection of COVID-19 variants

Genetic risk score predicts onset and severity of scoliosis in adolescents

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

New human organoid mimics the earliest developmental steps of the nervous system in embryos

Study: Immune responses may develop against other proteins produced by SARS-CoV-2

Study reviews natural drug candidates for potential treatment of COVID-19

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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