Immune System News and Research

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New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

A new clinical trial at the University of Cincinnati is studying the effectiveness of a new two-pronged immunotherapy treatment procedure to treat the most aggressive and deadly type of brain tumors, called glioblastomas. Originating from healthy brain cells, glioblastomas can form in any area of the brain.

25 Mar 2022

Researchers show how an important inhibitor binds to the A2A receptor

The A2A receptor regulates how vigorously the innate immune system attacks diseased cells.

25 Mar 2022

New model reveals how antibodies navigate pathogen surfaces like a child at play

A new study shows how antibodies select the antigens that they bind to, as they navigate the surface of pathogens like coronaviruses.

24 Mar 2022

New implantable biotechnology produces and releases CAR-T cells for attacking tumors

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors.

24 Mar 2022

INRS professor developing a glycoconjugate vaccine for melioidosis

The threat from Melioidosis is real. The bacterium that causes this infectious multisymptom illness is resistant to antibiotics, making diagnosis and treatment more complex and resulting in a mortality rate of up to 50%.

24 Mar 2022

U of A researcher receives $436,642 from NIH to study effects of SARS-COV-2 on the aortic valve

The National Institute of Health awarded $436,642 to associate professor of biomedical engineering, Kartik Balachandran, to study the downstream effects of acute respiratory syndrome coronavirus 2 on the aortic valve.

24 Mar 2022

UB-612 vaccine booster found to elicit high neutralizing antibody levels against SARS-CoV-2 Omicron

Researchers evaluated the effectiveness of a novel vaccine candidate UB-612 against 14 SARS-CoV-2 variants, including the latest variant of concern, Omicron.

24 Mar 2022

World Tuberculosis Day 2022: an interview with Dr. Maxine Caws

For World Tuberculosis Day 2022, News Medical spoke to Dr. Maxine Caws to raise awareness of this infectious disease.

24 Mar 2022

$Metabolic-immune interaction appears to be the cause of heart failure with preserved ejection fraction$

Metabolic-immune interaction appears to be the cause of heart failure with preserved ejection fraction

The dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body's response to metabolic stress and the immune system, according to a review article written by UT Southwestern researchers and colleagues.

23 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

Origins of Type 2 diabetes differ between males and females, research shows

Over the past four decades, global cases of Type 2 diabetes mellitus have skyrocketed. According to the World Health Organization, the number of people estimated to have the disease jumped from 108 million in 1980 to 422 million in 2014, with the fastest growth observed in low- and middle-income countries.

23 Mar 2022

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer.

23 Mar 2022

New nanoparticle-based COVID-19 vaccine platform could target other infectious diseases

Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use.

23 Mar 2022

People who consume sugar for extended periods have increased risk of autoimmune disease

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease.

23 Mar 2022

New York Blood Center and Columbia University partner to advance the use of mRNA technology in HIV vaccine study

New York Blood Center’s Project ACHIEVE and Columbia University’s Columbia Research Unit are working in partnership for the New York City effort to advance the use of messenger ribonucleic acid (mRNA) technology in an HIV preventive vaccine study – HVTN 302.

23 Mar 2022

Scientists identify a promising strategy for stopping Ebola virus polymerase

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

23 Mar 2022

Detection of immune and clotting dysfunction in plasma and saliva after SARS-CoV-2 infection

It is becoming increasingly clear that individuals recovering from acute coronavirus disease (COVID-19) may develop post-acute sequelae (Post-Acute Coronavirus Syndrome, PACS).

23 Mar 2022

Review: Common clinical features of pediatric antiphospholipid syndrome

Each year, around two of every 100,000 American adults receive a new diagnosis of antiphospholipid syndrome, or APS, an autoimmune disease known to cause inflammation and recurring, potentially fatal, blood clots.

22 Mar 2022

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

A human immune system is a lot like the board game Mouse Trap: it's a Rube Goldberg system of interacting parts. Only instead of a falling ball causing a tiny diver to leap into a tub - which, in turn, springs a trap on some plastic mice - proteins trigger other proteins to activate immune cells and direct them toward germs.

22 Mar 2022

Immunocompromised patients worry vaccine exemptions put them in peril

Charlie O'Neill received part of her husband's liver in a 2013 living donor transplant and has been taking drugs that suppress her immune system ever since to prevent her body from attacking the organ.

22 Mar 2022

Immune System News and Research

New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

Researchers show how an important inhibitor binds to the A2A receptor

New model reveals how antibodies navigate pathogen surfaces like a child at play

New implantable biotechnology produces and releases CAR-T cells for attacking tumors

INRS professor developing a glycoconjugate vaccine for melioidosis

U of A researcher receives $436,642 from NIH to study effects of SARS-COV-2 on the aortic valve

UB-612 vaccine booster found to elicit high neutralizing antibody levels against SARS-CoV-2 Omicron

World Tuberculosis Day 2022: an interview with Dr. Maxine Caws

Metabolic-immune interaction appears to be the cause of heart failure with preserved ejection fraction

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Origins of Type 2 diabetes differ between males and females, research shows

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

New nanoparticle-based COVID-19 vaccine platform could target other infectious diseases

People who consume sugar for extended periods have increased risk of autoimmune disease

New York Blood Center and Columbia University partner to advance the use of mRNA technology in HIV vaccine study

Scientists identify a promising strategy for stopping Ebola virus polymerase

Detection of immune and clotting dysfunction in plasma and saliva after SARS-CoV-2 infection

Review: Common clinical features of pediatric antiphospholipid syndrome

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

Immunocompromised patients worry vaccine exemptions put them in peril

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