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8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Researchers assess the efficacy of 8G3, a B-cell neutralizing antibody against SARS-CoV-2 variants, including the most recent Omicron variant.

3 Mar 2022

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

A new study published on the bioRxiv* preprint server has evaluated bacterial susceptibility during SARS-CoV-2 infection.

3 Mar 2022

WHO experts suggest antiviral drug for patients with non-severe covid-19 at highest risk of hospitalization

The antiviral drug molnupiravir is conditionally recommended for patients with non-severe covid-19 who are at highest risk of hospitalization, says a WHO Guideline Development Group of international experts in The BMJ today.

3 Mar 2022

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

A recent study analyzes IFNa subtypes for their therapeutic potential against SARS-CoV-2 and identified the underlying immune signatures and mechanisms.

3 Mar 2022

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

A recent study provides a better understanding of whether SARS-CoV-2 infection is linked with the occurrence of chilblains.

3 Mar 2022

Research uncovers a new molecular interaction mechanism for SARS-CoV2

The virus causing the current COVID-19 pandemic is the SARS-CoV-2. Soon after the pandemic outbreak in 2019, the ACE-2 protein, which is present on some of our cells´ surface, was identified as the receptor facilitating host cell viral entry.

3 Mar 2022

Study unravels why women are more susceptible to Alzheimer’s disease

Epidemiological studies have shown that women are twice as likely as men to develop Alzheimer's disease (AD), but the cause of this phenomenon has been unclear.

2 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

The prevalence of SARS-CoV-2 in environment and animal samples from the Huanan seafood market

A new study describes the surveillance of SARS-CoV-2 within the Huanan seafood market.

2 Mar 2022

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

The current study discusses a reliable ELISA that can detect three isotypes of antibody against three SARS-CoV-2 antigens.

2 Mar 2022

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

1 Mar 2022

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

University of Utah Health researchers are leading a five-year, $22-million nationwide clinical trial for NMDA receptor encephalitis––a type of autoimmune encephalitis that prompts the immune system to mistakenly attack the brain, causing confusion, memory loss, seizures, and symptoms similar to bipolar disorder and other psychiatric conditions.

1 Mar 2022

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Researchers used deep mutational scans to measure the effect of each amino-acid mutation in the receptor-binding domain of SARS-CoV-2 Wuhan-Hu-1, Alpha, Beta, Delta, and Eta variants.

1 Mar 2022

Study proposes structural explanation for immune evasion effect of SARS-CoV-2 BA.2 variant mutations S371L/F

Researchers proposed a structural mechanism to explain immune evasion effects of the two-point mutations, S371L and S371F, in the receptor-binding domain of the SARS-CoV-2 Omicron variant.

1 Mar 2022

Recombinant adenovirus vector vaccine generates mucosal antibodies against SARS-CoV-2

In a recent study posted to the bioRxiv* server, researchers assessed the immunogenicity of the self-developed recombinant adenovirus vector (rAd5) vaccine on macaques. They evaluated the efficacy of three candidate vaccines, ED88, ED90, and ED94, to select the most appropriate one for future development.

1 Mar 2022

Biophysical fitness profile of SARS-CoV-2 Delta variant

In a recent study posted to the bioRxiv* preprint server, researchers investigated the biophysical fitness landscape of the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

1 Mar 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Receptor News and Research

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

WHO experts suggest antiviral drug for patients with non-severe covid-19 at highest risk of hospitalization

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

Research uncovers a new molecular interaction mechanism for SARS-CoV2

Study unravels why women are more susceptible to Alzheimer’s disease

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

The prevalence of SARS-CoV-2 in environment and animal samples from the Huanan seafood market

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Study proposes structural explanation for immune evasion effect of SARS-CoV-2 BA.2 variant mutations S371L/F

Recombinant adenovirus vector vaccine generates mucosal antibodies against SARS-CoV-2

Biophysical fitness profile of SARS-CoV-2 Delta variant

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

MUSC study sheds light on better ways to prevent and treat colorectal cancer

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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