Clinical Trial News and Research

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Smartphone-based augmented reality app helps tackle the fear of spiders

Researchers from the University of Basel have developed an augmented reality app for smartphones in order to help people reduce their fear of spiders.

20 Sep 2021

Ask KHN-Politifact: Is my cloth mask good enough to face the delta variant?

In recent months, some European airlines have banned the use of cloth face coverings to control the spread of the coronavirus during air travel, instead favoring surgical masks — sometimes referred to as medical or disposable — and N95 respirators.

20 Sep 2021

EIT Health highlights the urgent need for harnessing data and AI to fight against Alzheimer’s disease

To coincide with World Alzheimer’s Month, EIT Health, an EU-backed network of best-in-class health innovators, has highlighted the urgent need to focus on implementing bolder approaches to the treatment of Alzheimer’s Disease post-pandemic.

20 Sep 2021

Many cancer survivors continue to suffer long-term burdensome symptoms, study shows

Previous standards of cancer follow-up care and support may no longer meet current needs as improvements in screening practices, early diagnosis and treatment of cancer have put long-term survival beyond five years following diagnosis within reach for more than half of patients in Europe.

20 Sep 2021

Immunotherapy treatment may be appropriate for patients with earlier stages of melanoma

An immunotherapy called pembrolizumab reduced cancer recurrence after surgery in patients with stage IIb and IIc melanoma, according to the results of an international, randomized phase III clinical trial led by UPMC Hillman Cancer Center.

20 Sep 2021

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study.

20 Sep 2021

Development of a potential pan-variant aerosol to manage COVID-19

Researchers hypothesized that if APN01 could be directly introduced into the airways of an infected person, it could locally neutralize SARS-CoV-2.

19 Sep 2021

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

A new study utilized MVA to develop vaccine candidates that were subsequently evaluated in animal models of congenital cytomegalovirus disease.

19 Sep 2021

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

In contrast to intramuscular vaccines, only nasal vaccines are able to block the virus in the nose by inducing local immunity in the nasal mucosa, i.e. the portal of entry and multiplication of the virus.

18 Sep 2021

Thousands of vulnerable hospital patients set to benefit from new COVID-19 treatment

Thousands of vulnerable NHS patients in hospital due to COVID-19 are set to benefit from a ground-breaking new antibody treatment, the government has announced today (17 September 2021).

18 Sep 2021

mAb treatment can rapidly select for SARS-CoV-2 resistance, suggests study

A study evaluates the efficacy of a mAb to prevent disease progression in non-hospitalized persons with symptomatic SARS-CoV-2 infection.

17 Sep 2021

GammaDelta Therapeutics initiates first-in-human phase 1 trial of GDX012 for the treatment of acute myeloid leukemia

GammaDelta Therapeutics Ltd., a biotechnology company pioneering the discovery and development of allogeneic gamma delta T cell therapies for cancer, today announced that it has initiated a first-in-human Phase I clinical trial evaluating GDX012 for the treatment of acute myeloid leukemia.

17 Sep 2021

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

17 Sep 2021

Childhood maltreatment causes neurobiological alterations in early stages of life

A paper published in the journal Psychological Medicine confirms the existence of neurobiological alterations in early stages of life in minors exposed to maltreatment.

16 Sep 2021

CXCR6/CXCL16 axis has significant role in the immuno-pathogenesis of severe COVID-19

In a study published on the preprint server medRxiv*, scientists studying the SARS-CoV-2 genome have identified a region linked with the disease severity.

16 Sep 2021

Single dose of typhoid conjugate vaccine found to be safe and effective in Malawian kids

A new study, published today in the New England Journal of Medicine, finds a single dose of typhoid conjugate vaccine (TCV) – the only typhoid vaccine licensed for children as young as 6 months – is safe and 84 percent effective in protecting against typhoid in Blantyre, Malawi.

16 Sep 2021

Novel combination therapy approach to keep leukemia at bay

In chronic leukemias, blocking the overactive kinase JAK2 by a targeted therapy approach is only mitigating the patients' symptoms, but cannot truly change the course of the disease.

16 Sep 2021

Study looks at drug resistance in BRAF-mutated gliomas

Looking to understand why some brain tumors with a specific mutation can start to reject drugs commonly used to treat them, CU Cancer Center member Jean Mulcahy Levy, MD, led researchers from institutions around the country - including several from the University of Colorado School of Medicine - to study samples of brain tumors before and after being treated with the drug.

16 Sep 2021

Study identifies probable cause of Alzheimer’s disease

Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities for Australia's second-leading cause of death.

16 Sep 2021

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Clinical Trial News and Research

Smartphone-based augmented reality app helps tackle the fear of spiders

Ask KHN-Politifact: Is my cloth mask good enough to face the delta variant?

EIT Health highlights the urgent need for harnessing data and AI to fight against Alzheimer’s disease

Many cancer survivors continue to suffer long-term burdensome symptoms, study shows

Immunotherapy treatment may be appropriate for patients with earlier stages of melanoma

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

Development of a potential pan-variant aerosol to manage COVID-19

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

Thousands of vulnerable hospital patients set to benefit from new COVID-19 treatment

mAb treatment can rapidly select for SARS-CoV-2 resistance, suggests study

GammaDelta Therapeutics initiates first-in-human phase 1 trial of GDX012 for the treatment of acute myeloid leukemia

Multiple sclerosis patients elicit robust T-cell responses to mRNA COVID-19 vaccines

Childhood maltreatment causes neurobiological alterations in early stages of life

CXCR6/CXCL16 axis has significant role in the immuno-pathogenesis of severe COVID-19

Single dose of typhoid conjugate vaccine found to be safe and effective in Malawian kids

Novel combination therapy approach to keep leukemia at bay

Study looks at drug resistance in BRAF-mutated gliomas

Study identifies probable cause of Alzheimer’s disease

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

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