Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Humalog 200 units/ml KwikPen insulin gets marketing approval in EU for treatment of diabetes

Eli Lilly and Company today announced that the European Commission has granted marketing authorisation for Humalog 200 units/ml KwikPen (insulin lispro 200 units/ml) for the treatment of diabetes in adults.

3 Oct 2014

Researchers receive $4 million NIH grant to bioengineer miniature pancreas in a dish

Although type 1 diabetes can be controlled with insulin injections and lifestyle modifications, major advances in treating the disease have not been made in more than two decades and there remain fundamental gaps in what is understood about its causes and how to halt its progression.

3 Oct 2014

Weekly growth hormone on course for phase III in children

A long-lasting formulation of human growth hormone appears to be as effective as standard daily treatment in paediatric patients with growth hormone deficiency, researchers reported at the European Society of Paediatric Endocrinology annual meeting in Dublin, Ireland.

2 Oct 2014

Empirical sulphonylurea therapy an option for neonatal diabetes

A report of empirical sulphonylurea therapy in neonatal diabetes prior to genetic diagnosis highlights contrasting approaches to the problem.

2 Oct 2014

Managing diabetes and intensive exercise: an interview with Dr Rafael Castol, Team Novo Nordisk

Team Novo Nordisk is a professional cycling team that races at UCI Pro Continental level. It's the first ever team to be made up of athletes diagnosed with Type 1 diabetes. The team was created three years ago, and is part of the Changing Diabetes initiative developed by Novo Nordisk.

From Novo Nordisk 1 Oct 2014

Galmed Pharmaceuticals purchases EndoPAT devices, accessories from Itamar Medical

Galmed Pharmaceuticals Ltd. ("Galmed"), a clinical-stage biopharmaceutical company focused on the development and commercialization of a once-daily, oral medication for the treatment of liver diseases and cholesterol gallstones, announced today that it purchased 60 EndoPAT™ devices and accessories from Itamar Medical Ltd.

29 Sep 2014

MicroBiome Therapeutics' NM 505 drug can improve tolerability of metformin

MicroBiome TherapeuticsTM LLC, today reported positive topline results from a proof of concept study testing whether its investigational drug, NM 505, can improve the tolerability of metformin, the first-line therapy for Type 2 diabetes worldwide.

26 Sep 2014

Working long hours in jobs of low socioeconomic status can increase the risk of diabetes

It is widely accepted that working long hours can be detrimental to one's health; not least because it leaves less time free to exercise and can cause stress and sleep disturbances.

25 Sep 2014

Ohio State researchers develop novel anticancer peptide vaccines and inhibitors

Researchers have developed two new anticancer peptide vaccines and two peptide inhibitors as part of a larger peptide immunotherapy effort at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

25 Sep 2014

Research report on biopharmaceutical and vaccine manufacturing markets

The total biopharmaceutical manufacturing market is growing, according to Kalorama Information's report, Biopharmaceutical and Vaccine Production Markets.

24 Sep 2014

Dynamical glucometry may uncover new ways of understanding diabetes

For millions of people in the United States living with Type 1 or Type 2 diabetes, measuring the daily rise and fall of blood glucose (sugar) is a way of life.

24 Sep 2014

Fast decline in insulin sensitivity seen in pre-diabetic South Asians

People of south Asian descent who have Type 2 diabetes show a more rapid decline in fasting glucose levels than White individuals even before they develop the disease, new findings from the Whitehall II study suggest.

18 Sep 2014

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden.

18 Sep 2014

Gut hormone-drug combination therapy more effective at improving type 2 diabetes

Combined treatment with a drug that mimics the action of a gut hormone and basal insulin is more effective at improving blood sugar control than other anti-diabetic treatments, with similar rates of hypoglycaemia (dangerously low blood sugar levels) and greater weight loss, a systematic review and meta-analysis published in The Lancet shows.

15 Sep 2014

ChromaDex signs NIAGEN supply agreement with Healthy Directions

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, cosmetic and pharmaceutical industries, announced today that it has entered into an ingredient supply agreement with Healthy Directions, a direct-to-consumer nutritional supplement retailer and wholly-owned subsidiary of Helen of Troy Limited.

11 Sep 2014

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition.

11 Sep 2014

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Researchers at the University of California, San Diego School of Medicine, in partnership with ViaCyte, Inc., a San Diego-based biotechnology firm specializing in regenerative medicine, have launched the first-ever human Phase I/II clinical trial of a stem cell-derived therapy for patients with Type 1 diabetes.

11 Sep 2014

Insulin News and Research

Further Reading

Humalog 200 units/ml KwikPen insulin gets marketing approval in EU for treatment of diabetes

Researchers receive $4 million NIH grant to bioengineer miniature pancreas in a dish

Weekly growth hormone on course for phase III in children

Empirical sulphonylurea therapy an option for neonatal diabetes

Managing diabetes and intensive exercise: an interview with Dr Rafael Castol, Team Novo Nordisk

Galmed Pharmaceuticals purchases EndoPAT devices, accessories from Itamar Medical

MicroBiome Therapeutics' NM 505 drug can improve tolerability of metformin

Working long hours in jobs of low socioeconomic status can increase the risk of diabetes

Ohio State researchers develop novel anticancer peptide vaccines and inhibitors

Research report on biopharmaceutical and vaccine manufacturing markets

Dynamical glucometry may uncover new ways of understanding diabetes

Fast decline in insulin sensitivity seen in pre-diabetic South Asians

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Gut hormone-drug combination therapy more effective at improving type 2 diabetes

ChromaDex signs NIAGEN supply agreement with Healthy Directions

FDA approves Contrave extended-release tablets for chronic weight management

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Lilly and Boehringer Ingelheim's insulin glargine product gets marketing approval from EC

Beta-O2 receives grant from JDRF to study ßAir bio-artificial pancreas for treatment of T1D

Regular consumption of mango by obese adults may lower blood sugar levels

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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