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Breakthrough discovery in HIV research opens path to new, better therapies

New research on the human immunodeficiency virus (HIV) structure has revealed a promising novel drug target for treating it.

23 Apr 2020

Using 'own' immune cells to fight infectious diseases including COVID-19

A provocative paper from Duke-NUS Medical School, published in the Journal of Experimental Medicine in March 2020, discusses the possibilities of creating new receptors on a sick person's own immune cells as a means of controlling the infection. This therapy is already being used to treat certain cancers with marked success.

22 Apr 2020

Study identifies a promising new strategy for combating malaria

Researchers have discovered a promising new strategy for combating malaria, a mosquito-borne parasite that claims nearly a half-million lives each year.

22 Apr 2020

Have we found a new malaria vaccine?

A new study published in the journal Nature in April 2020 reports on a malaria protein antibody that appears to protect resistant children from severe disease, showing promise in the fight against malaria, a new study found. Almost 500,000 people die of malaria every year.

22 Apr 2020

Adults with spinal cord injury are at higher risk of developing mental health disorders

In a new study, published in Mayo Clinic Proceedings, researchers from Michigan Medicine find adults with spinal cord injury are at a higher risk of developing mental health disorders, including depression and anxiety, compared to adults without the condition.

22 Apr 2020

PiCoVacc vaccine candidate for COVID-19 effective in animal trials

In a new study available on the bioRxiv preprint server, a group of researchers from China report on the pilot-scale production of a purified inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus vaccine candidate (PiCoVacc), shown to induce virus-specific neutralizing antibodies in rats, mice, and non-human primates.

21 Apr 2020

New study may offer a breakthrough in treating telomere diseases

Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely.

21 Apr 2020

A new, potential treatment for nonalcoholic steatohepatitis with fibrosis

In the 2020 April 21 issue of Journal of Hepatology, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis (NASH) with fibrosis and suggested a possibility of the new therapy using cytoglobin (CYGB) inducer for clinical application.

21 Apr 2020

COVID-19 and immunodeficiency

COVID-19 disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a highly infectious disease. As of today, over 170,000 people worldwide have succumbed to the infection. Reports have shown that some comorbidities and illnesses raise the risk of getting infected and also influence the severity of the disease. Having a compromised immune system can also drastically raise the risk of getting COVID-19.

21 Apr 2020

Hypertensive pregnancy disorders may lead to mental health conditions in children

Hypertensive pregnancy disorders, especially preeclampsia, a form of high blood pressure during pregnancy, may lead to adverse mental health conditions in children, according to new research published today in Hypertension, an American Heart Association journal.

20 Apr 2020

Type 2 diabetics secrete too much glucagon when α-cells become insulin resistant

Patients with type 2 diabetes secrete not only too little insulin but also too much glucagon, which contributes to poor blood glucose control.

20 Apr 2020

A new combinatorial therapy for treatment of liver cancer

In the latest issue of Molecular Therapy, Skoltech and MIT researchers have published a new combinatorial therapy for the treatment of liver cancer.

20 Apr 2020

Study shows how interactions between microbiome and the immune system contribute to liver disease

A new study by researchers in the Quadram Institute has provided insights into how interactions between gut microbes and cells of the immune system contribute to cholestatic liver disease.

20 Apr 2020

Hypertensive pregnancy disorders may lead to mental health conditions in children

Hypertensive pregnancy disorders, especially preeclampsia, may lead to adverse mental health conditions in children.

20 Apr 2020

Study: Early changes in microbiome development can impact health and disease later in life

A team of researchers at Children's Hospital of Philadelphia (CHOP) has characterized how the gut microbiome develops in the first hours of infancy, providing a critical baseline for how changes in this environment can impact health and disease later in life.

17 Apr 2020

Greater occurrence of infections correlates with future cancer diagnosis

Patients experienced a greater occurrence of infections in the years preceding a cancer diagnosis.

17 Apr 2020

Landmark 30-year study describes clinical course of patients with Crigler-Najjar syndrome

A new study summarizes more than 30 years of clinical experience and describes the clinical course of 28 individuals homozygous for damaging mutations in the UGT1A1 gene who were born between 1984 and 2015 with Crigler-Najjar syndrome.

17 Apr 2020

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020

Review investigates stem cell therapy as potential new treatment for preeclampsia

Preeclampsia is the leading cause of death and disability, for both mothers and babies, killing approximately 76,000 mothers and 500,000 babies globally every year. Despite this, the only cure at present is to deliver the placenta and the baby, with the potential for long term complications.

16 Apr 2020

Aspirin associated with reduction in risk of several digestive tract cancers

Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers.

15 Apr 2020

Liver News and Research

Breakthrough discovery in HIV research opens path to new, better therapies

Using 'own' immune cells to fight infectious diseases including COVID-19

Study identifies a promising new strategy for combating malaria

Have we found a new malaria vaccine?

Adults with spinal cord injury are at higher risk of developing mental health disorders

PiCoVacc vaccine candidate for COVID-19 effective in animal trials

New study may offer a breakthrough in treating telomere diseases

A new, potential treatment for nonalcoholic steatohepatitis with fibrosis

COVID-19 and immunodeficiency

Hypertensive pregnancy disorders may lead to mental health conditions in children

Type 2 diabetics secrete too much glucagon when α-cells become insulin resistant

A new combinatorial therapy for treatment of liver cancer

Study shows how interactions between microbiome and the immune system contribute to liver disease

Hypertensive pregnancy disorders may lead to mental health conditions in children

Study: Early changes in microbiome development can impact health and disease later in life

Greater occurrence of infections correlates with future cancer diagnosis

Landmark 30-year study describes clinical course of patients with Crigler-Najjar syndrome

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

Review investigates stem cell therapy as potential new treatment for preeclampsia

Aspirin associated with reduction in risk of several digestive tract cancers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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