Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Older cancer patients taking multiple medications are at higher risk of hospitalization

As adults age, they accumulate a number of medications for chronic conditions. Older patients take anywhere between 5-15 medications per year, which increases the risk that some of the drugs will counteract each other.

21 Mar 2020

Immunotherapy treatment shows promise for some patients with advanced rare cancers

A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of advanced, hard-to-treat rare cancers.

20 Mar 2020

Researchers highlight urgent need for public health leadership during COVID-19 pandemic

For decades, public health officials have directed the containment of emerging pandemics - perhaps most notably - the worldwide eradication of smallpox starting in the early to mid-1960s.

19 Mar 2020

Substances linked to bladder cancer found in the urine of e-cigarette users

An analysis of evidence from multiple scientific studies found six substances that have a strong link to bladder cancer in the urine of people who had used electronic cigarettes and sometimes other tobacco products, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and NYU Langone Health reported.

19 Mar 2020

Study offers new insight into genetic alterations associated with osteosarcoma

A study by researchers at the National Cancer Institute, part of the National Institutes of Health, offers new insight into genetic alterations associated with osteosarcoma, the most common cancerous bone tumor of children and adolescents.

19 Mar 2020

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven't been able to predict which patients won't benefit from the treatment and should explore other options.

19 Mar 2020

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

The cover for issue 11 of Oncotarget features Figure 6, "Effects of AZD8186 in combination with anti-PD1 on syngeneic models," by Owusu-Brackett, et al.

18 Mar 2020

Vaxxas' novel high-density microarray patch can deliver vaccines safely and effectively

Vaxxas, a clinical-stage biotechnology company commercializing a novel vaccination platform, today announced the publication in the journal PLoS Medicine of groundbreaking clinical research indicating the broad immunological and commercial potential of Vaxxas' novel high-density microarray patch.

17 Mar 2020

New type of artificial binding proteins for blocking sugar structures on cell surfaces

The laboratory directed by Arne Skerra, Professor of Biological Chemistry, has its focus on designing artificial binding proteins for therapeutic applications.

17 Mar 2020

African-American men less likely to use more targeted biopsy option for prostate cancer

Researchers at the University of Cincinnati have found in a retrospective study that African-American men are less likely to use a more targeted biopsy option for prostate cancer, despite an increased incidence in this group of patients.

17 Mar 2020

Beijing Tide Pharmaceutical and Insilico Medicine announce cancer drug discovery collaboration

Beijing Tide Pharmaceutical Co., Ltd., a subsidiary of Sino Biopharmaceutical Limited, and Insilico Medicine, an artificial intelligence company developing end-to-end drug discovery pipelines, announced today that they are entering a collaboration, applying artificial intelligence technology to drug discovery, to jointly accelerate the process for multiple types of cancer treatment.

16 Mar 2020

Overview of prognostic and predictive factors in pancreatic cancer

Oncotarget Volume 11, Issue 10 reported that there are not standardized predictive biomarkers able to identify patients who benefit most from treatments.

13 Mar 2020

A miRNA signature linked to local-regional failure and overall survival after pancreatic cancer resection

The cover for issue 10 of Oncotarget features Figure 3, "Overall survival (OS) for high (red) versus low (black) risk groups in the (A) OSU, (B) TCGA, and (C) SNU resected cohorts," by Wolfe, et al.

13 Mar 2020

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic stroke-cohort 1: 37 atherothrombotic patients and 6 controls, ischemic stroke-cohort 2: 80 atherothrombotic patients and 184 controls.

13 Mar 2020

UC Riverside biochemist and Atomwise form new joint venture

Over the past few years, biochemist John Jefferson Perry at the University of California, Riverside, has collaborated on a number of projects with Atomwise Inc., a company that uses artificial intelligence, or AI, for drug discovery.

13 Mar 2020

Preserving kidney function in patients with diabetic kidney disease

Diabetic kidney disease, which affects between 20 to 40 percent of people with diabetes, is a serious complication that can ultimately lead to end-stage kidney disease--a life-threatening condition that requires either dialysis or kidney transplant.

13 Mar 2020

Post-diagnosis disparities drive worse outcomes for Black and Hispanic children with brain cancer

Cancer researchers have known for years that Black and Hispanic patients have worse outcomes than their non-Hispanic White peers.

12 Mar 2020

People in rural Honduras embrace multiphasic cancer screening opportunities

The burden of cancer is on the rise in low- and middle-income countries (LMICs) such as Honduras.

11 Mar 2020

Scientists receive €2.45 million funding for leukemia research

Leukemia stem cells are considered to be the starting point of leukemia; their elimination is a basic prerequisite for a successful long-term therapy. Scientists at Heidelberg University Hospital, the Heidelberg Institute for Stem Cell Technology and Experimental Medicine at the German Cancer Research Center, the German Cancer Research Center and the European Molecular Biology Laboratory have now obtained research funding of €2.45 million from the German Federal Ministry of Education and Research as part of the junior research alliance LeukoSyStem.

11 Mar 2020

Oncology News and Research

Further Reading

Older cancer patients taking multiple medications are at higher risk of hospitalization

Immunotherapy treatment shows promise for some patients with advanced rare cancers

Researchers highlight urgent need for public health leadership during COVID-19 pandemic

Substances linked to bladder cancer found in the urine of e-cigarette users

Study offers new insight into genetic alterations associated with osteosarcoma

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

Vaxxas' novel high-density microarray patch can deliver vaccines safely and effectively

New type of artificial binding proteins for blocking sugar structures on cell surfaces

African-American men less likely to use more targeted biopsy option for prostate cancer

Beijing Tide Pharmaceutical and Insilico Medicine announce cancer drug discovery collaboration

Overview of prognostic and predictive factors in pancreatic cancer

A miRNA signature linked to local-regional failure and overall survival after pancreatic cancer resection

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

UC Riverside biochemist and Atomwise form new joint venture

Preserving kidney function in patients with diabetic kidney disease

Post-diagnosis disparities drive worse outcomes for Black and Hispanic children with brain cancer

People in rural Honduras embrace multiphasic cancer screening opportunities

Scientists receive €2.45 million funding for leukemia research

Event guide: 10th CAR-TCR Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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