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No seroprevalence observed against SARS-CoV-2 in wild ruminants in Germany

A team of scientists from Germany has recently conducted a serological screening on wild animals to assess seroprevalence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other pathogenic viruses related to domestic ruminants.

27 Feb 2022

Will Omicron BA.2 become the next dominant variant?

A new study presents a comprehensive analysis of the potential of both Omicron BA.2 and BA.3 to become the next dominant circulating SARS-CoV-2 strain.

27 Feb 2022

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A new study discusses the emergence of new variants of SARS-CoV-2 that can escape antibody-mediated neutralization, as opposed to other Sarbecoviruses.

27 Feb 2022

A promising new vaccine for SARS-CoV-2 and influenza

Researchers create a vaccine candidate that could protect against both SARS-CoV-2 and IAVs.

27 Feb 2022

Targeting a specific protein can help prevent or delay prostate cancer progression

Targeting a specific protein that is often overexpressed in prostate cancer can help prevent or delay the disease from spreading to other parts of the body, according to a study led by Cedars-Sinai Cancer investigators.

25 Feb 2022

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Researchers conducted a comprehensive and systematic analysis of functional SARS-CoV-2 antibody profiles in a controlled randomized trial of severe COVID-19 hospitalized individuals treated with COVID-19 CCP.

25 Feb 2022

Research could pave the way for adoption of precision medicine approaches for COVID-19

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why?

25 Feb 2022

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Researchers examined systemic B and T cell responses 16 weeks after BNT162b2 vaccination, and the potency of vaccine-induce neutralizing antibodies, in hemodialysis patients and healthcare workers with no comorbidities.

25 Feb 2022

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection.

24 Feb 2022

Serological responses to heterologous COVID-19 mRNA vaccination in older individuals

Researchers assess the serological response to a real-world COVID-19 vaccination strategy in older individuals who resided in long-term care facilities.

24 Feb 2022

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

A Stony Brook University physician-scientist has identified that mucosal-associated invariant T (MAIT) cells, an unconventional form of immune cell, exercise several complex roles during healthy and disease states.

24 Feb 2022

Should SARS-CoV-2 Omicron be considered a serotype?

A recent article provides evidence for and against the hypothesis of SARS-CoV-2 serotypes.

24 Feb 2022

Study provides a promising new avenue for development of anti-obesity treatments

An anti-tumor drug promotes weight loss in mice at low doses by activating a natural hunger-suppressing pathway, according to a new study publishing February 24th in the open-access journal PLOS Biology by Jiang Wei Wu and colleagues at Northwest A&F University in Shaanxi, China.

24 Feb 2022

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Researchers demonstrated that decorating the capsid surface of adenovirus vaccine vectors with a newly discovered protein superglue, DogTag/DogCatcher generates potent SARS-CoV-2-specific humoral and cellular immunity.

24 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Third dose of mRNA-based COVID-19 vaccine efficiently recalls Omicron-reactive B cell memory

A new study examined how the quantity and quality of antibody and memory B cell responses to SARS-CoV-2 change temporally and with the number of exposures to antigens.

24 Feb 2022

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

Researchers investigated whether residual SARS-CoV-2 antigens and RNA are present in tissues samples of long COVID-19 patients beyond the convalescent phase of COVID-19.

24 Feb 2022

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Researchers investigated the probability of Omicron BA.2 reinfections following SARS-CoV-2 Omicron BA.1 initial infection by whole genomic sequencing in the period of dominance of these subvariants in Denmark.

24 Feb 2022

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Researchers used a systems immunology approach to analyze the immune states of healthy and non-obese subjects who recovered from mild COVID-19 and compared them with age- and sex-matched COVID-19-naive controls.

24 Feb 2022

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

A new study posted to the bioRxiv* preprint server reports on the development of anti-RBD immunoglobulin Y (IgY) antibodies from chicken eggs to block the binding of the viral RBD to human ACE2 receptors. This approach has several advantages since chicken egg-derived IgY can be edible and polyclonal can target multiple epitopes, enhancing neutralizing activity.

23 Feb 2022

Receptor News and Research

No seroprevalence observed against SARS-CoV-2 in wild ruminants in Germany

Will Omicron BA.2 become the next dominant variant?

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A promising new vaccine for SARS-CoV-2 and influenza

Targeting a specific protein can help prevent or delay prostate cancer progression

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Research could pave the way for adoption of precision medicine approaches for COVID-19

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

Serological responses to heterologous COVID-19 mRNA vaccination in older individuals

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

Should SARS-CoV-2 Omicron be considered a serotype?

Study provides a promising new avenue for development of anti-obesity treatments

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Third dose of mRNA-based COVID-19 vaccine efficiently recalls Omicron-reactive B cell memory

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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