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New dual-target therapy offers hope for better breast cancer treatment

Researchers, led by the University of Melbourne's Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at the Peter Doherty Institute of Infection and Immunity (Doherty Institute), in collaboration with Pfizer, have discovered new insights into possible future treatments for breast cancer.

12 Feb 2025

Physical activity improves sleep quality in older adults during social isolation

A new research paper was published in Aging (Aging-US) on January 15, 2025, in Volume 17, Issue 1, titled "Association between physical activity practice and sleep quality of older people in social isolation during the COVID-19 pandemic and Health Guidelines and future studies for the post-COVID period: a systematic review."

11 Feb 2025

Lung signals trigger blood clot formation in cancer patients

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and University of California San Diego Health. Clots are the second-leading cause of death among cancer patients with advanced disease or aggressive tumors.

11 Feb 2025

GUK1 enzyme plays crucial role in lung cancer metabolism and growth

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, and it can shapeshift in unpredictable ways to evade treatment.

10 Feb 2025

University of Oulu advances biosensor technology for disease detection

The University of Oulu is at the forefront of developing cutting-edge biosensor technology that could revolutionize the early diagnosis and treatment of diseases.

10 Feb 2025

Novel MSC-based therapy provides hope for ocular GVHD treatment

Graft-versus-host disease (GVHD) is a common and severe complication that occurs after stem cell transplantation, where the donor's immune cells attack the recipient's tissues.

10 Feb 2025

Study explores how nanoplastics could affect child's immune system during pregnancy

Allergies and asthma are widespread diseases that could arise during embryonal development in the womb.

6 Feb 2025

Ethnicity and mental health impact brain health in rural older adults

A new research paper was published in Aging (Aging-US) on November 27, 2024, in Volume 17, Issue 1, titled "Neurocognitive disparities: investigating ethnicity and mental health in rural aging adults."

6 Feb 2025

Researchers discover how RNA molecules influence multiple generations

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies.

4 Feb 2025

Topical ABT-263 treatment improves wound healing in aging skin

A new research paper was published by Aging (Aging-US) on December 3, 2024, in Volume 17, Issue 1, titled "Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing."

4 Feb 2025

Blocking a protein could halt the growth of fast-growing cancers

Preventing the cell's protein factories from making the notorious cancer-causing protein MYC could stop out-of-control tumors.

4 Feb 2025

New microscopy technique uncovers 'ribosome cooperativity' in difficult situations

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells.

31 Jan 2025

Targeting MYCN and MDM2 offers new hope for cancer therapy

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

EU-funded Vigilant network aims to develop broad-spectrum antiviral drugs

Pandemics threaten both human health and the global economy. Vaccines are an essential part of the fight against pandemics, but they are only available months after the outbreak

23 Jan 2025

Research shows epigenetic aging in the blood as potential breast cancer marker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) on December 5, 2024, Volume 16, Issue 22, titled "DNA-methylation age and accelerated epigenetic aging in blood as a tumor marker for predicting breast cancer susceptibility."

21 Jan 2025

Cigarette smoke alters immune cell function in the lungs

Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of effective treatments.

17 Jan 2025

Pioglitazone may help prevent painful skin ulcers in people with Werner syndrome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 2, 2024, entitled "Less frequent skin ulcers among patients with Werner syndrome treated with pioglitazone: findings from the Japanese Werner Syndrome Registry."

16 Jan 2025

Scientists discover why cancer cells die differently after radiotherapy

Scientists at Children's Medical Research Institute have solved a big mystery in cancer research – why cells die in different ways following radiotherapy.

13 Jan 2025

New skeletal tissue could revolutionize regenerative medicine and cartilage repair

An international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering.

9 Jan 2025