Metabolic Disorders News and Research

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Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds.

4 Apr 2017

Patent analysis reveals that saffron bioactives can be used to treat multiple disorders

Increased stress levels, sleep disorders and obesity have become hallmarks of present lifestyle. These conditions are often correlated with serious health problems such as cancer, diabetes, cerebral ischemia, stroke, etc.

27 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

Why don’t patients always discuss hyperglycemia with their doctor?

Hyperglycemia occurs when a patient has higher than normal blood sugar levels. If the levels are very high, consistently 13-14 or above, the patient will start to feel tired, thirsty and feel the urge to go to the toilet frequently to pass urine (micturition).

17 Mar 2017

Hormone secreted by bone cells can suppress appetite, mice study reveals

A hormone secreted by bone cells can suppress appetite, according to mouse studies conducted by Columbia University Medical Center researchers.

8 Mar 2017

Researchers develop new tool that quickly reveals metabolic fluxes in cells

If we were to take photographs at the underground stations in Barcelona, we would see the number of people waiting, find out what time the rush hour takes place and deduce why some stations are busier than others.

23 Feb 2017

Upstate opens new public cord blood bank in New York

Upstate Medical University opens the Upstate Cord Blood Bank, only the second public cord blood bank in New York and one of only 32 in the US.

20 Feb 2017

UT Southwestern scientists unravel role of PARP enzymes in major cellular activities

A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.

16 Feb 2017

Estrogen regulates specific exosome-packed microRNAs in blood circulation, study shows

A study at the Gerontology Research Center demonstrated that, in blood circulation, the exosome-carried messenger molecule profile differs between post- and premenopausal women.

15 Feb 2017

Review shows lipid nanoparticles as highly promising delivery systems in gene therapy

Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy.

14 Feb 2017

New study sheds light on how prenatal BPA exposure increases obesity risk

An expectant mother's exposure to the endocrine-disrupting chemical bisphenol A (BPA) can raise her offspring's risk of obesity by reducing sensitivity to a hormone responsible for controlling appetite, according to a mouse study published in the Endocrine Society's journal Endocrinology.

8 Feb 2017

FDA grants permission to market new Seeker System for screening rare metabolic disorders in newborns

The U.S. Food and Drug Administration today permitted marketing of the Seeker System for the screening of four, rare Lysosomal Storage Disorders (LSDs) in newborns.

3 Feb 2017

Non-invasive technique for examining fatty tissues could revolutionize medicinal drug testing

That's the hope of Associate Professor Noriyuki Yanaka and researchers at Hiroshima University who have developed a non-invasive way to assess the anti-inflammatory properties of fortified health foods and medications.

31 Jan 2017

Oral devices improve sleep in OSA patients but may not reduce key heart disease risk factors

In patients with severe obstructive sleep apnea (OSA), oral appliances that treat the condition by moving the lower jaw forward appear to improve sleep but not reduce key risk factors for developing heart and other cardiovascular disease, according to new research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

28 Jan 2017

TSU scientists developing new method to treat autism and cognitive disorders

Scientists at the Tomsk State University are exploring myokines, proteins that are produced in the muscles during physical activities.

26 Jan 2017

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks, University at Buffalo researchers have found.

19 Jan 2017

Workplace-based sleep health program can reduce injuries and disability in firefighters

Many firefighters suffer acute and chronic sleep deficiency and misalignment of their circadian rhythm (body clock) due to extended shifts and long work weeks.

12 Jan 2017

Vitamin D supplementation improves metabolic syndrome in mice

It is well known that a diet high in fat can trigger a metabolic syndrome, a group of symptoms that pose as risk factors for diabetes and heart disease.

22 Dec 2016

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Cambridge Innovation Capital plc, a Cambridge-based investor in technology and healthcare companies, and IP Group plc, the developer of intellectual property-based businesses, announce the creation of Microbiotica Ltd, a newly formed spin-out company from the UK’s Wellcome Trust Sanger Institute based at the Wellcome Genome Campus in Hinxton, Cambridge.

21 Dec 2016

Disturbances in the body’s carbon monoxide metabolism linked to circadian disruption

Chronobiologists from Charité - Universitätsmedizin Berlin have shown that the body's carbon monoxide metabolism is closely linked to the body's circadian (internal) clock.

7 Dec 2016