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Regulating cell acidity could transform autoimmune disease treatments

What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients' cells? Genetic screening may have unlocked a path for treating the severe inflammation associated with many immune diseases by regulating one protein's role in helping another protein control cell acidity, according to new research published in Cell by a team from the Perelman School of Medicine at the University of Pennsylvania.

11 Mar 2025

Microplastics found to promote antibiotic resistance in bacteria

Microplastics-tiny shards of plastic debris-are all over the planet. They have made their way up food chains, accumulated in oceans, clustered in clouds and on mountains, and been found inside our bodies at alarming rates.

11 Mar 2025

Herpes infection through the nose can lead to anxiety, motor impairment and cognitive deficits

Herpes simplex virus-1 (HSV-1) is commonly known for causing blisters and sores. But in some cases, the virus can migrate to the eye or nervous system, causing severe, chronic symptoms.

10 Mar 2025

Study reveals genes critical for tuberculosis survival during transmission

Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person's lungs to another person's during coughing, sneezing or talking, according to researchers from Weill Cornell Medicine and the Massachusetts Institute of Technology.

10 Mar 2025

Vanderbilt researchers aim to use AI to develop antibody therapies for any target

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

8 Mar 2025

Study uncovers how transposons use telomeres for survival in bacteria

Transposons, or "jumping genes" – DNA segments that can move from one part of the genome to another – are key to bacterial evolution and the development of antibiotic resistance.

7 Mar 2025

New CRISPR-enriched metagenomics method for detecting antibiotic resistance genes in wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals.

4 Mar 2025

Cheese isn't just food—it’s a microbiome booster, study confirms

Scientists reveal that cheese-derived bacteria, particularly less abundant strains, can shape gut microbiota and enhance metabolic functions, underscoring the impact of fermented foods on gut health.

3 Mar 2025

Groundbreaking studies reveal how DNA folding guides sperm cell development

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell.

3 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Study identifies key role of JMJD1C in acute myeloid leukemia

Acute myeloid leukemia (AML) is one of the most aggressive and genetically complex cancers, marked by the unchecked growth of immature myeloid cells.

3 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Skin organoids show promise for treating frostbite injuries

Frostbite is a severe cold injury that affects millions worldwide, often resulting in prolonged recovery, scarring, and long-term complications such as chronic pain and dysfunction.

3 Mar 2025

MEDI method unlocks new way to decode dietary habits

"Tell me what you eat and I will tell you who you are"—this well-known saying accurately describes the new MEDI method for decoding dietary habits from DNA fragments that was developed at Med Uni Graz in cooperation with an international research team.

2 Mar 2025