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Prefrontal cortex biopsies during deep brain stimulation surgery do not increase risk of adverse events

Obtaining prefrontal cortex biopsies during deep brain stimulation (DBS) surgery in living patients does not increase the risk of adverse events or cognitive decline compared to standard DBS procedures that don't involve biopsies, a team of clinical research scientists at the Icahn School of Medicine at Mount Sinai has demonstrated.

4 Sep 2025

Auburn researchers uncover staph’s superglue-like grip on human skin

Imagine a child with eczema who scratches a patch of irritated skin. A tiny opening forms, invisible to the eye.

4 Sep 2025

Eppendorf introduces next generation mechanical pipettes

Eppendorf, a leading international life science company that develops, manufactures, and distributes instruments, consumables, and services for use in laboratories around the world, today announced the commercial launch of the Eppendorf Research 3 neo, designed to deliver accurate and precise results for accelerated volume selection, and optimized ergonomics.

4 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

Chronic stress and fatty diet disrupt brain-liver circuit leading to diabetes

This study discovered a circuit in the brain that connects stress with increased glucose and therefore may link stress to type 2 diabetes. In stressful situations, this circuit from the amygdala to the liver naturally provides a burst of energy.

3 Sep 2025

Breakthrough reveals how viruses efficiently pack genetic material

Researchers at San Diego State University and Michigan State University are shedding new light on how viruses meticulously pack their genetic material - a breakthrough that could help researchers engineer antivirals and gene therapies.

2 Sep 2025

Aptamer signs therapeutic development agreement with Invizius

Aptamer Group plc, the developer of next-generation synthetic binders for the life sciences industry, is pleased to announce that it has signed a new therapeutic development agreement with Invizius, a clinical-stage biotechnology company focused on second-generation complement system therapies for inflammatory, fibrotic, and autoimmune diseases.

From Aptamer Group 2 Sep 2025

Scientists discover molecular brake that limits T cell attack on tumors

In a discovery that could expand the array of current cancer immunotherapy treatments, scientists at Harvard Medical School have identified a new molecular brake that hinders the ability of T cells to attack tumors.

1 Sep 2025

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). This study identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS.

29 Aug 2025

Structural design advances pave the way for next-generation wearable sensors

Tactile sensors are widely used in robotics, prosthetics, wearable devices, and healthcare monitoring. These devices detect and convert external stimuli such as pressure and force into electrical signals, facilitating effective environmental detection.

29 Aug 2025

Healthy gut bacteria capsules show long-term benefits for obese teenagers

Can a capsule of healthy gut bugs change the future of obesity treatment? New findings from the University of Auckland’s Liggins Institute suggest it might.

29 Aug 2025

New advances offer hope in the fight against KRAS-driven pancreatic cancer

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

28 Aug 2025

Killifish study reveals multi-generational impacts of exposure to crude oil and flame retardants

A tiny fish with transparent embryos is helping University of California, Davis, researchers shed light on how exposure to crude oil and flame retardants can affect behavior, skeletal growth, cardiac health and other internal functions in offspring and subsequent generations.

28 Aug 2025

Wayne State project advances efforts toward automated diabetes care

Despite advances in insulin therapy and automated delivery systems, people with Type 1 diabetes (T1D) still face a daily struggle: manually dosing insulin before meals.

28 Aug 2025

Aptamer Group introduces novel biomarker discovery service

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, today announced the launch of its biomarker discovery service, offering researchers in pharmaceutical, biotechnology, and diagnostic development an innovative approach to identify and validate new disease markers.

28 Aug 2025

Belgian researchers uncover how dendritic cells respond to lipid nanoparticles in vaccines

Belgian scientists have uncovered new details about how the immune system responds to vaccines. Dendritic cells, which are key immune messengers that help kick-start the body's defenses, show specific responses to lipid nanoparticles.

27 Aug 2025

Novel monoclonal antibodies show promise in preventing severe mpox disease

A team from the Microbiology Department at the Icahn School of Medicine at Mount Sinai has discovered three powerful monoclonal antibodies from a person who had previously been infected with mpox (formerly known as monkeypox).

26 Aug 2025

Mount Sinai researchers develop MARQO to revolutionize cancer tissue analysis

Scientists at the Icahn School of Medicine at Mount Sinai have developed a powerful new computational tool that could transform how cancer tissues are analyzed and help pave the way for more personalized treatments.

25 Aug 2025

iconPCR™: Powering the next wave of metagenomics and microbiome discovery

The landscape of metagenomics and microbiome research is evolving at breakneck speed. As sequencing technologies improve and the demand for high-resolution, bias-free microbial data grows, the bottleneck is shifting from sequencing itself to the quality of upstream sample preparation.

From n6 23 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025