RNA Sequencing News and Research

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Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Researchers at the Max Planck Florida Institute for Neuroscience have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons.

15 Jul 2021

Mutations in the Epsilon variant contribute to SARS-CoV-2 immune evasion

Three mutations in the Epsilon coronavirus spike protein dampen the neutralizing potency of antibodies induced by current vaccines or past COVID infections.

6 Jul 2021

New software tool can help identify gene regulators more efficiently

A team of scientists at the University of Illinois Chicago has developed a software tool that can help researchers more efficiently identify the regulators of genes. The system leverages a machine learning algorithm to predict which transcription factors are most likely to be active in individual cells.

1 Jul 2021

Study provides important insights into early stages of SARS-CoV-2 infection

Researchers in the UK have provided important new insights into the early stages of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

30 Jun 2021

New study investigates alternative ways to prevent, treat kidney infections

Ten IU School of Medicine researchers out of a team of 11 scientists, are responsible for the findings of a new study they conducted to investigate alternative ways to treat kidney infections.

29 Jun 2021

Understanding new resting phase of stem cells could help put glioma tumors to sleep

Christopher Plaisier, an assistant professor of biomedical engineering in the Ira A. Fulton Schools of Engineering at Arizona State University, and Samantha O'Connor, a biomedical engineering doctoral student in the Plaisier Lab, are leading research into a new stage of the stem cell life cycle that could be the key to unlocking new methods of brain cancer treatment.

25 Jun 2021

City of Hope researchers identify how breast cancer cells acquire resistant traits

City of Hope, a world-renowned cancer research and treatment center, has identified how cancer cells in patients with early-stage breast cancer change and become resistant to hormone or combination therapies, according to a new study published in Nature Cancer.

24 Jun 2021

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

The most comprehensive molecular study to date of the brains of people who died of COVID-19 turned up unmistakable signs of inflammation and impaired brain circuits.

22 Jun 2021

Researchers analyze how breast implant surfaces influence immune response

Rice University bioengineers collaborated on a six-year study that systematically analyzed how the surface architecture of breast implants influences the development of adverse effects, including an unusual type of lymphoma.

21 Jun 2021

Study: Cancer cells grown in culture dishes have less parity with their human sources

In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

18 Jun 2021

Researchers create the most comprehensive atlas of human transcriptome

Together with Baylor College of Medicine and the world's leading sequencing company, Illumina, researchers at Ghent University have built one of the most comprehensive catalogues of the human transcriptome ever.

18 Jun 2021

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

17 Jun 2021

How the common cold can provide protection against COVID-19

In a recent study, researchers found that prior infection with the rhinovirus can provide a more effective immune response against SARS-CoV-2 infection.

17 Jun 2021

New noninvasive biomarker can be used in the diagnosis of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and can progress to liver cirrhosis, liver failure or cancer. Currently, nonalcoholic steatohepatitis (NASH) diagnosis requires an invasive liver biopsy which can lead to procedural complications.

17 Jun 2021

Anti-viral treatment can stop the spread of lab modeled SARS-CoV-2 by 99.5%

A new approach focusing on cellular repair may be an effective strategy to address the pandemic.

16 Jun 2021

Anti-viral treatment can stop the spread of lab modeled SARS-CoV-2 by 99.5%

A new approach focusing on cellular repair may be an effective strategy to address the pandemic.

16 Jun 2021

UIC discovery may lead to new treatments for alcohol use disorder and depression

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.

14 Jun 2021

Delays and shortages hit SARS-CoV-2 genomic surveillance program

A new study from the Institute of Bioinformatics and Applied Biotechnology (IBAB), Bengaluru, India, provides an overview of how well this important monitoring mechanism is functioning around the world. The team has released their findings as a preprint on the bioRxiv* server.

14 Jun 2021

New technique uses high-throughput sequencing to obtain ultra-high-resolution images of gene expression

The 30,000 or so genes making up the human genome contain the instructions vital to life. Yet each of our cells expresses only a subset of these genes in their daily functioning. The difference between a heart cell and a liver cell, for example, is determined by which genes are expressed--and the correct expression of genes can mean the difference between health and disease.

11 Jun 2021

RNA Sequencing News and Research

Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Mutations in the Epsilon variant contribute to SARS-CoV-2 immune evasion

New software tool can help identify gene regulators more efficiently

Study provides important insights into early stages of SARS-CoV-2 infection

New study investigates alternative ways to prevent, treat kidney infections

Understanding new resting phase of stem cells could help put glioma tumors to sleep

City of Hope researchers identify how breast cancer cells acquire resistant traits

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

Researchers analyze how breast implant surfaces influence immune response

Study: Cancer cells grown in culture dishes have less parity with their human sources

Researchers create the most comprehensive atlas of human transcriptome

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

How the common cold can provide protection against COVID-19

New noninvasive biomarker can be used in the diagnosis of NAFLD

Anti-viral treatment can stop the spread of lab modeled SARS-CoV-2 by 99.5%

Anti-viral treatment can stop the spread of lab modeled SARS-CoV-2 by 99.5%

UIC discovery may lead to new treatments for alcohol use disorder and depression

Delays and shortages hit SARS-CoV-2 genomic surveillance program

New technique uses high-throughput sequencing to obtain ultra-high-resolution images of gene expression

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