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New tool predicts which cancer patients will respond positively to immunotherapy

An international group led by Dr Banafshe Larijani, an Ikerbasque researcher seconded to the Biofisika Institute (UPV/EHU-University of the Basque Country, CSIC), has developed a new diagnostic method making it possible to accurately predict which cancer patients will respond positively to immunotherapy.

16 Nov 2020

Research uncovers a new underlying cause of heart attack

Heart attacks strike suddenly and have a range of different triggers. Researchers from Charité - Universitätsmedizin Berlin and the German Centre for Cardiovascular Research (DZHK) were able to uncover a further underlying cause.

10 Nov 2020

Human immune system may play key role in shaping the microbiome composition

The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch.

30 Oct 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

Rapid CD169 assay for COVID-19 screening

Researchers in France have conducted a study demonstrating the sensitivity of a rapid flow cytometry assay that could be used to screen for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

27 Oct 2020

New technique could propel personalized cancer treatments

When it comes to defeating cancer, some immune cells are mightier than others. But even the best-trained eye and today's advanced scientific tools have trouble discerning the most powerful tumor-fighting cells from the rest.

23 Oct 2020

Study shows how genetic predisposition contributes to the development of multiple sclerosis

About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors.

22 Oct 2020

Template for COVID-19 management in a rural health system

As the COVID-19 pandemic continues to challenge existing health networks, a new study published on the preprint server medRxiv in October 2020 reports on a strategy to address existing health care disparities in rural and urban areas of the USA. This should draw attention to the need for more such systems to ensure proper rural healthcare in the current and future pandemics.

20 Oct 2020

The connection between severe COVID-19 and white blood cell counts

However, in other research, white blood cells' exact roles and subtypes in severe COVID-19 are still unclear. The team writes, "It is unknown if blood cell counts before infection are associated with the risk of developing severe COVID-19." They explained that the numbers of these cell types could be influenced by several factors such as age, gender, disease status, and medications.

19 Oct 2020

Scientists discover key enzyme involved in the development of autoimmune diseases

Scientists affiliated with the Center for Research on Inflammatory Diseases (CRID http://crid.fmrp.usp.br), hosted by the University of São Paulo (USP) in Brazil, have discovered that an enzyme involved in key metabolic processes also plays a role in immune cell differentiation and hence in the development of autoimmune diseases.

19 Oct 2020

Cytotoxic NK cells also have immunological memory function

Good news for the human immune system: researchers from MedUni Vienna's Departments of Dermatology and Surgery have managed to ascribe an immunological memory function to a subset of cytotoxic NK cells, which have hitherto been regarded as antigen-non-specific.

19 Oct 2020

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

A patient with end-stage and rapidly progressing soft-tissue cancer whose tumor did not respond to standard treatment, had a "rapid and complete response" to a novel combination of immunotherapy, according to new research published by a team of scientists from John Theurer Cancer Center at Hackensack University Medical Center and the Georgetown Lombardi Comprehensive Cancer Center, both of whom are part of the Georgetown Lombardi Comprehensive Cancer Center Consortium.

16 Oct 2020

Characterization of prognostic markers to predict COVID-19 severity

A team of scientists from the United Kingdom has revealed that markers of endothelial cell injury are associated with severe and fatal outcome of coronavirus disease 2019 (COVID-19). The study is currently available on the medRxiv* preprint server.

14 Oct 2020

Are antibiotics being over prescribed in COVID-19?

A new study published on the preprint server medRxiv in October 2020 shows that the baseline levels of inflammatory markers and C-reactive protein (CRP) in relation to antibiotic administration can rule out bacterial co-infections and help reduce the unnecessary use of antibiotics.

13 Oct 2020

Scientists develop new type of precise therapeutic vaccine against leukemia

Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.

12 Oct 2020

Case report of arthritis in a COVID-19 patient

The current paper published in the The Lancet Rheumatology discusses arthritis in a 58-year-old white woman with COVID-19 of less than severe intensity.

7 Oct 2020

TCR's quantity and clonality are linked to prognosis of colorectal cancer

Colorectal cancer (CRC) is the third most common cancer in the world, with more than one and a half million new cases diagnosed annually.

7 Oct 2020

Low lymphocyte count before COVID-19 heightens death risk

Researchers at the University of Rochester Medical Center have conducted a study suggesting that having a low white blood cell count (lymphocytopenia) prior to exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be associated with an increased risk of dying from coronavirus disease 2019 (COVID-19).

6 Oct 2020

Severe COVID-19 in pregnancy increases risk for adverse maternal and neonatal outcomes

A new study published in the American Journal of Obstetrics and Gynecology in September 2020 reports the impact of severe COVID-19 on pregnancy, making an important contribution to the management of the condition in this subgroup of patients.

5 Oct 2020

Sebum changes in COVID-19 patients, for future testing and prognosis

Now, a new study published on the preprint server medRxiv in September 2020 shows that sebum lipids change in COVID-19. This could help develop a cheap and straightforward method of non-invasive diagnosis.

5 Oct 2020