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Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

In a recently published article in the journal Frontiers in Immunology, scientists have reviewed the existing literature on antiviral and anti-inflammatory efficacy of resveratrol-based inhaled formulations in preventing SARS-CoV-2 infection and reducing COVID-19 severity.

9 Jun 2021

New technology allows rapid analysis and mapping of new potential virus variants

Variants of viruses, such as that causing COVID-19, can now be quickly studied in the laboratory, even before they emerge in nature and become a major public health challenge.

9 Jun 2021

Researchers identify novel gene that controls sleep/wake cycle in mice

That internal nagging feeling that drives you to seek sleep at night and wake in the morning to eat, work, and play, is, it turns out, genetic, and it's not just in people.

9 Jun 2021

Researchers map potential toxicity of lanthanide metals used in medicine

Lanthanides are rare-earth heavy metals with useful magnetic properties and a knack for emitting light. Researchers had long assumed that lanthanides' toxicity risk was low and therefore safe to implement in a number of high-tech breakthroughs we now take for granted: from OLEDs (organic light-emitting displays)¬¬ to medical MRIs and even hybrid vehicles.

9 Jun 2021

SARS-CoV-2 B.1.1.345 variant carrying E484K mutation detected in New York

The report, published in the journal Clinical Infectious Diseases, revealed that the variant detected has been spreading at an alarming rate since November. By February 2021, it accounted for 12.3 percent of all cases in the area.

8 Jun 2021

How SARS-CoV-2 variant B.1.1.7 adapted to evade innate immunity

Researchers in the United States and the UK have conducted a study showing how the B.1.1.7 (Alpha) lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adapted to suppress host innate immune responses in lung epithelial cells.

8 Jun 2021

What is the role of monoclonal antibody therapy in treating COVID-19?

A new study has been published in the journal Vaccines that deals with the present state of research on using mAbs for the treatment of the COVID-19 disease. Many clinical trials are being conducted to evaluate the efficacy and safety of several newly designed mAbs. Some of the mAbs are directed towards immune system responses, i.e., non-SARS-CoV-2 specific mAbs, while others are devised to neutralize the SARS-CoV-2 protein structure, i.e., SARS-CoV-2 specific mAbs.

8 Jun 2021

Researchers review environmental risk assessments for recombinant COVID-19 viral vector vaccines

In a recent review, published in the journal Vaccines, researchers in Belgium look at the recombinant viral vector-vaccine candidates that are primarily against SARS-CoV-2 still in development and discuss their features from an environmental risk point of view.

8 Jun 2021

Bacteria causing urinary tract infections can originate in meat-production chain

In young women, Staphylococcus saprophyticus is a main cause of urinary tract infections (UTI), reaching 20% prevalence. Understanding the epidemiology of this microorganism can help identify its origin, distribution, causes, and risk factors.

8 Jun 2021

New drug shows promise against lung cancer caused by genetic mutation

The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial.

8 Jun 2021

Distinct spike protein mutations in SARS-CoV-2 variant in Russia

Additionally, a novel variant has recently been characterized by researchers from Russia in the journal Viruses. The variant, first discovered in January 2021 in Northwest Russia, is characterized by distinct spike protein mutations.

7 Jun 2021

International travelers may pick up destination-specific antimicrobial resistance genes, study reveals

Travelers abroad may pick up bacteria and other vectors containing genes conferring antimicrobial resistance which remain in the gut when returning to their home country, according to a study published in Genome Medicine.

7 Jun 2021

The genetic diversity of SARS-CoV-2 in the USA

In a research paper recently uploaded to the preprint server medRxiv by Capoferri et al. (June 4th, 2021), the genetic diversity of SARS-CoV-2 through each phase is examined in detail using publicly available genomic data available from before 2021, highlighting the need to continuously track and assess the evolution of the virus to ensure the future efficacy of the currently available vaccines.

7 Jun 2021

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

In a recent research paper currently available on the bioRxiv* preprint server, scientists in the US used genome-scale CRISPR knockout screens to identify factors that promote infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), revealing the potential for broad-spectrum activity across the coronavirus family.

7 Jun 2021

Risk of SARS-CoV-2 transmission aboard aircraft is low: A review of evidence

Researchers in Romania, the UK, and Canada have systematically reviewed the evidence available on the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aboard aircraft.

7 Jun 2021

ERS Genomics and genOway enter CRISPR/Cas9 agreement

ERS Genomics Limited today announced a non-exclusive license agreement granting genOway past and future access to ERS Genomics’ CRISPR/Cas9 patent portfolio.

7 Jun 2021

International travelers often return home with new bacterial strains, confirms study

Carried like stowaways in the guts of international travelers, new and potentially deadly strains of antimicrobial resistant superbugs may be coming to a community near you, suggests new research from Washington University School of Medicine in St. Louis.

7 Jun 2021

Comparison of immunological profiles of SARS-CoV-2 variants

Mutations to the spike protein and receptor-binding domain are responsible for these changes in immunogenic profile, and in a paper recently uploaded to the open access journal Antibiotics by Ambrose et al. (May 6th, 2021) these mutations are correlated with various disease parameters by in silico methods, finding that particular features are responsible for the increased infectiousness and lesser disease severity observed in these lineages.

6 Jun 2021

SARS-CoV-2 genome analysis reveals new 'Mexican variant'

A research group of the Department of Pharmacy and Biotechnology of the University of Bologna analyzed more than one million SARS-CoV-2 genome sequences.

5 Jun 2021

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. c

5 Jun 2021

Genome News and Research

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

New technology allows rapid analysis and mapping of new potential virus variants

Researchers identify novel gene that controls sleep/wake cycle in mice

Researchers map potential toxicity of lanthanide metals used in medicine

SARS-CoV-2 B.1.1.345 variant carrying E484K mutation detected in New York

How SARS-CoV-2 variant B.1.1.7 adapted to evade innate immunity

What is the role of monoclonal antibody therapy in treating COVID-19?

Researchers review environmental risk assessments for recombinant COVID-19 viral vector vaccines

Bacteria causing urinary tract infections can originate in meat-production chain

New drug shows promise against lung cancer caused by genetic mutation

Distinct spike protein mutations in SARS-CoV-2 variant in Russia

International travelers may pick up destination-specific antimicrobial resistance genes, study reveals

The genetic diversity of SARS-CoV-2 in the USA

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

Risk of SARS-CoV-2 transmission aboard aircraft is low: A review of evidence

ERS Genomics and genOway enter CRISPR/Cas9 agreement

International travelers often return home with new bacterial strains, confirms study

Comparison of immunological profiles of SARS-CoV-2 variants

SARS-CoV-2 genome analysis reveals new 'Mexican variant'

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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