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Pine bark naturally reduces osteoarthritis knee pain

Affecting more than 10 million Americans, Osteoarthritis of the knee (OA) is one of the five leading causes of disability among the elderly.

5 Dec 2007

Discovery of potential "getting drunk" gene

A variant of a gene involved in communication among brain cells has a direct influence on alcohol consumption in mice, according to a new study by scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), and the U.S. Army.

5 Dec 2007

HIV-infected infants respond poorly to childhood vaccination

It is known that HIV-infected children who do not receive appropriate antiretroviral drugs experience immune depression, and may become susceptible to infectious diseases that would otherwise be prevented by childhood immunization.

5 Dec 2007

Early abortions may be made easier for women in Britain

The British government is considering making early abortions available to women at doctors surgeries.

5 Dec 2007

Scientists characterize Alzheimer's neurotoxin structure - potential new treatment approaches

Amyloid plaques, the hallmark of Alzheimer's disease, are clumps of fiber-like misfolded proteins which many experts think cause this devastating neurodegenerative disease.

4 Dec 2007

Positive results from trial of investigational anti-epilepsy drug Brivaracetam

UCB has announced data demonstrating that anti-epileptic drug (AED) brivaracetam, with the proposed trade name Rikelta, administered as an adjunctive treatment in adults with refractory epilepsy with partial onset seizures, significantly reduced seizure frequency and had a side-effect profile comparable to placebo.

4 Dec 2007

Treating patients with psychiatric disorders for hepatitis C

People with severe mental illnesses are far more likely to be infected with Hepatitis C virus compared to the general population, however, they often do not get treatment for their liver disease because current antiviral therapies have known psychiatric side effects.

4 Dec 2007

Re-engineered Gleevec reduces heart risks

Using a new bottom-up approach for rational drug design, researchers at Rice University and the University of Texas M. D. Anderson Cancer Center have reengineered the powerful anticancer drug imatinib - best known by its brand name Gleevec - to more specifically target one type of cancer while potentially curbing a rare life-threatening cardiotoxic side effect.

4 Dec 2007

sLRP1-alpha provides relief from neuropathic pain

Injury to peripheral nerves (the causes of which include shingles, HIV-AIDS, toxins, alcoholism, repetitive motion disorders, surgery, and cancer) causes neuropathic pain, which differs from ordinary pain and is usually perceived as a steady burning, pins and needles, electric shock sensations, and/or tickling.

4 Dec 2007

Genetic markers for mental illness

Researchers have discovered natural genetic differences that might help predict the most effective antipsychotic drugs for particular patients with mental disorders such as schizophrenia, Parkinson's and drug addiction.

4 Dec 2007

New upper limit defined for normal ALT in adolescent males

A new cohort study of adolescent offenders in Australia has identified an upper limit for alanine aminotransferase (ALT) that is more sensitive for the diagnosis of liver disease.

4 Dec 2007

Mini transplant patients' outcomes similar using related and unrelated donor cells

People who undergo nonmyeloablative stem-cell transplants, or "mini transplants," for leukemia, lymphoma and other blood cancers have comparable outcomes regardless of whether they receive tissue-matched stem cells from a related or unrelated donor, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

4 Dec 2007

Scientists develop optical device that allows them to peer through the eyes of a mouse and monitor cells passing in bloodstream

A team of researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have developed an optical device that allows them to peer through the eyes of a mouse and monitor the cells passing through its bloodstream.

4 Dec 2007

Johns Hopkins Children's Center receives Gates funding for tuberculosis bacterium tracker

Johns Hopkins Children's Center has received a $946,000 grant from the Bill & Melinda Gates Foundation to design a system that visually tracks the behavior of the tuberculosis bacterium in the body and its response to current and new drug treatments.

4 Dec 2007

Genetic testing for severe type of migraine may help identify new treatment options

People with a severe type of migraine in which one side of the body becomes weak should consider genetic testing, according to research that has found familial genes for this type of migraine in people who did not have family members experiencing the problem.

4 Dec 2007

Genes discovered that protect against heart damage from chemotherapy

A series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart.

4 Dec 2007

Hydrogen sulfide provides clues to a longer life

Hydrogen sulfide, or H2S, the chemical that gives rotten eggs their sulfurous stench - and the same compound that researchers at Fred Hutchinson Cancer Research Center successfully have used to put mice into a state of reversible metabolic hibernation - has now been shown to significantly increase life span and heat tolerance in the nematode worm, or C. elegans.

4 Dec 2007