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From successful aging to severe dementia

A recently published special issue of the Journal of Alzheimer's Disease contains the contributions from experts in the field of aging, dementia and Alzheimer's disease, who attended the "Fourth Annual Meeting on Brain aging and Dementia - From successful aging to severe dementia”, Held in Perugia in October 2006 under the auspices of the Italian Psychogeriatric Association, a member of the International Psychogeriatric Association, the meeting celebrates the centenary of Alzheimer's first description of the disease.

16 Nov 2007

How inhibitor-of-apoptosis chemicals kill tumors

Chemical compounds specially designed to neutralize proteins that would otherwise allow tumor cells to cheat death have been recognized for some time by scientists as a promising new avenue for cancer therapy.

16 Nov 2007

Prescription medication dosages often incorrect for obese patients

As if severely overweight people didn't already have enough health concerns, experts are raising another red flag - the possibility that some of their prescription medications, especially antibiotics, may not be prescribed at the appropriate dosage and could be ineffective.

16 Nov 2007

Rising drug expenditures for ADHD

The NHS is likely to face a 10-fold increase in the cost of drugs prescribed to children and adolescents with attention-deficit/hyperactivity disorder (ADHD) in the decade to 2012.

16 Nov 2007

Cethromycin achieves all endpoints in second pivotal Phase III Trial for treatment for pneumonia

Advanced Life Sciences Holdings, Inc. (Nasdaq: ADLS), today announced positive results from Trial CL-05, the second of two pivotal phase III clinical trials designed to assess the safety and effectiveness of cethromycin, a novel once-a-day oral antibiotic for the treatment of mild-to-moderate community acquired pneumonia (CAP), the sixth leading cause of death in the United States.

16 Nov 2007

Biomarkers for Alzheimer's can be trusted in clinical trials

The best-established biomarkers for Alzheimer’s disease have a low natural variation over two years. The results speak for the inclusion of these biomarkers in clinical trials of novel drugs against Alzheimer’s disease.

16 Nov 2007

Stem cells from cloned monkeys - a breakthrough or an ethical nightmare?

In an important breakthrough scientists in the United States have cloned monkey embryos to create embryonic stem cells.

15 Nov 2007

Drug to treat children with bipolar disorder gets priority review

An anti-psychotic drug already approved in the U.S. to treat adults and adolescents with schizophrenia may soon be available for youngsters age 10 to 17 years of age suffering from bipolar disorder.

15 Nov 2007

Experts say obese women should be refused fertility treatment

A fertility organisation in Britain is saying that severely obese women should be barred from having National Health Service fertility treatment until they have lost weight.

15 Nov 2007

Christmas is coming and so is bird flu!

It is feared that tens of thousands of turkeys will be slaughtered across Britain in efforts to contain the spread of the deadly H5N1 bird flu.

15 Nov 2007

Top selling diabetes drug to carry back box warning

The government watchdog body in the U.S., The Food and Drug Administration (FDA), has placed a "black box" warning on the popular drug Avandia.

15 Nov 2007

Scientists zero in on the cellular machinery that enables neurons to fire

Toy robots with removable body parts - you probably had fun swapping their heads, imagining how it would affect their behavior. Scientists supported by the National Institutes of Health have been performing similar experiments on ion channels - pores in our nerve cells - to sort out the channels' key functional parts.

15 Nov 2007

GlaxoSmithKline implements changes to the US product label for Avandia

GlaxoSmithKline announced today that it is implementing changes to the US product label for Avandia(R) (rosiglitazone maleate), based on an extensive and thorough review by the FDA of myocardial ischemia data on Avandia, the most widely studied oral anti-diabetic medicine available.

15 Nov 2007

Head-to-head comparison of Forteo and Fosamax

The osteoporosis drug Forteo works better than Fosamax to strengthen bones in arthritis patients with prednisone-induced osteoporosis, according to a new study from a researcher at the University of Alabama at Birmingham (UAB.)

15 Nov 2007

Petition aims to stem the flood of dangerous drugs reaching Americans

In a petition filed with the U.S. Food and Drug Administration, an international coalition of scientists and doctors seeks to compel the agency to stem the flood of dangerous drugs reaching American consumers by mandating the use of scientifically superior non-animal testing methods when those alternatives exist.

15 Nov 2007

Lonesome people may have lower levels of specific brain hormone

The anxiety and aggression that result from social isolation have been traced to altered levels of an enzyme that controls production of a brain hormone.

15 Nov 2007

Captopril may limit radiation kidney damage in bone marrow transplant patients

Researchers at the Medical College of Wisconsin in Milwaukee have found that the risk of radiation injury in normal tissue after exposure may be reduced by a drug in common use. Their study in press appears in the on line issue of the International Journal of Radiation Oncology, Biology and Physics.

15 Nov 2007

FDA adds warning for heart attacks to type 2 diabetes drug Avandia

The U.S. Food and Drug Administration announced today that the manufacturer of Avandia (rosiglitazone), a drug used to treat type 2 diabetes, has agreed to add new information to the existing boxed warning in the drug's labeling about potential increased risk for heart attacks.

14 Nov 2007

EDMA calls for empowering people with diabetes

Type 2 diabetes and its complications are frequently diagnosed too late and the complications are often detected only at the time of diagnosis, concludes the European Parliament in its 2006 Written Declaration on Diabetes.

14 Nov 2007

UK hospitals short changing women with heart failure

Women with heart failure are less likely than men to receive recommended investigations and treatment, when admitted to hospital as an emergency, reveals an extensive UK survey, published ahead of print in the journal Heart.

14 Nov 2007