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Two uveitis drugs perform similarly in a head-to-head clinical trial

Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis, an eye disease that accounts for up to 15% of blindness in the U. S.

11 Sep 2019

Lung-MAP study: Majority of cancer patients don't understand genomic test results

A majority of cancer patients don't understand key aspects of the genomic test results they receive as participants in biomarker-driven clinical trials, according to a first-of-its-kind pilot study conducted under the Lung Cancer Master Protocol.

10 Sep 2019

NIAID experts call for innovative research on STIs

Sexually transmitted infections, or STIs, pose a significant public health challenge. Globally, more than one million new STI cases are diagnosed each day.

10 Sep 2019

Oral antibiotics that kill gut microorganisms can alter immune response to flu vaccines

The normal human gut microbiome is a flourishing community of microorganisms, some of which can affect the human immune system. In a new paper published this week in Cell, researchers found that oral antibiotics, which can kill gut microorganisms, can alter the human immune response to seasonal influenza vaccination.

8 Sep 2019

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

Small-cell clones in proliferating epithelia – tissues that line all body surfaces – organize very differently than their normal-sized counterparts, according to a recent study from the Stowers Institute for Medical Research.

6 Sep 2019

New program aims to prevent unnecessary hospital admissions for older adults

Preventing stressful, and often unnecessary, hospital admissions for older Australians living in residential aged care facilities is the aim of a new $1.9 million program funded by the Australian Government’s Medical Research Future Fund.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

NIH trial aims to improve drug discovery for ischemic stroke

The NIH has announced it will fund a nationwide preclinical trial focusing on robust testing of new treatments for acute ischemic stroke.

4 Sep 2019

Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations

Researchers at Boston Medical Center and Boston University School of Medicine, in collaboration with Columbia University Irving Medical Center, are leading a national, multi-site study aimed to achieve earlier diagnosis of transthyretin cardiac amyloidosis.

4 Sep 2019

Sustained drop in cholesterol and blood pressure reduces lifetime risk of heart, circulatory diseases

Modest and sustained decreases in blood pressure and cholesterol levels reduces the lifetime risk of developing fatal heart and circulatory diseases, such as heart attack and stroke, according to research part-funded by the British Heart Foundation and supported by the National Institute for Health Research.

4 Sep 2019

New cardio trial shows reduced wait times and hospital admissions

A major new study led by Flinders University Professor Derek Chew shows that up to 70% of patients presenting to Australian hospital emergency departments with chest pain could be safely discharged in less time than they currently are under standard Australian protocols.

4 Sep 2019

Novel approach could help prevent sepsis in burn patients

Immediately following severe burns, bacteria reach the wound from different sources, including the patient's skin, gastrointestinal tract, respiratory tracts and health care-related human contact.

4 Sep 2019

New pathological mediator of ALS found

A research collaboration based in Japan has found a new pathological mediator of amyotrophic lateral sclerosis, which could have further implications for understanding the molecular breakdown that gives rise to the neurodegenerative disease that affects nearly half a million people around the world.

3 Sep 2019

Unique Victorian databank on childhood hearing loss to go global

A unique Victorian databank that profiles children with hearing loss will help researchers globally understand why some children adapt and thrive, while others struggle.

30 Aug 2019

JAMA review: Clinicians encouraged to consider social determinants screening and referrals

The Feinstein Institutes for Medical Research Professor and Senior Vice President Karina W. Davidson, PhD, MASc, reviews clinical practices for social determinants of health screening and referrals in the September 17 issue of The Journal of the American Medical Association.

29 Aug 2019

A detailed map to understand how viruses infect human cells

Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect.

29 Aug 2019

New optical technology heralds exciting potential for mammalian behavioral studies

In an article published in the peer-reviewed, open-access SPIE publication Neurophotonics, "A multi-site microLED optrode array for neural interfacing," researchers present an implantable optrode array capable of exciting below-surface neurons in large mammal brains at two levels, both by structured-light delivery and large-volume illumination.

29 Aug 2019

Researchers analyze people’s initial immune response to dengue fever

Researchers have come one step closer to understanding how our immune system responds to acute dengue fever, a disease that has affected hundreds of thousands of people in Southeast Asia this summer alone.

29 Aug 2019

New type 2 diabetes drug associated with reduced risk of heart failure and death

The new type of drugs for type 2 diabetes, the so-called SGLT2 inhibitors, are associated with a reduced risk of heart failure and death as well as of major cardiovascular events, a major Scandinavian registry study led from Karolinska Institutet reports in The BMJ.

29 Aug 2019

Drug combination could improve survival of lung transplant patients

Lung transplantation can prolong the lives of patients with end-stage lung disease, but the median survival rate after lung transplant is less than six years, which has improved only slightly in recent decades.

28 Aug 2019

Medical Research News and Research

Two uveitis drugs perform similarly in a head-to-head clinical trial

Lung-MAP study: Majority of cancer patients don't understand genomic test results

NIAID experts call for innovative research on STIs

Oral antibiotics that kill gut microorganisms can alter immune response to flu vaccines

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

New program aims to prevent unnecessary hospital admissions for older adults

Large-scale study maps the genetic underpinnings of early TB progression

NIH trial aims to improve drug discovery for ischemic stroke

Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations

Sustained drop in cholesterol and blood pressure reduces lifetime risk of heart, circulatory diseases

New cardio trial shows reduced wait times and hospital admissions

Novel approach could help prevent sepsis in burn patients

New pathological mediator of ALS found

Unique Victorian databank on childhood hearing loss to go global

JAMA review: Clinicians encouraged to consider social determinants screening and referrals

A detailed map to understand how viruses infect human cells

New optical technology heralds exciting potential for mammalian behavioral studies

Researchers analyze people’s initial immune response to dengue fever

New type 2 diabetes drug associated with reduced risk of heart failure and death

Drug combination could improve survival of lung transplant patients

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