Tumor News and Research

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Discovery points to new drug targets that could prevent cancer spread

Any cancer cell migrating from a tumor to set up shop elsewhere in the body will face a brutal attack from an immune system programmed to seek and destroy abnormal cells.

22 Aug 2022

Researchers reveal details of two key transition points in the development of pancreatic tumors

Pancreatic cancer has few treatment options and limited survival, with only 9% of patients still living five years after diagnosis.

22 Aug 2022

Study shows encouraging results for robotic IVC thrombectomy

Kidney cancer is not always confined to the kidney. In advanced cases, this cancer invades the body's biggest vein, the inferior vena cava (IVC), which carries blood out of the kidneys back to the heart.

19 Aug 2022

Scientists identify new driver for rare type of liver cancer

Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver.

19 Aug 2022

Researchers visualize antigen-bound T-cell receptor at atomic resolution

T cells are our immune system’s customized tools for fighting infectious diseases and tumor cells. On their surface, these special white blood cells carry a receptor that recognizes antigens.

18 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

Study contributes to better understanding of the changes in kinase activity in renal cell carcinoma

A new research paper was published in Oncotarget on August 4, 2022, entitled, "Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors."

17 Aug 2022

UW cardiologists employ catheter-delivered device to retrieve a benign tumor from the heart

Interventional cardiologists at the UW Medicine Heart Institute in Seattle recently performed a first-in-human procedure, successfully employing a catheter-delivered device to retrieve a benign tumor from inside a patient's heart.

17 Aug 2022

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands.

16 Aug 2022

Non-invasive biomarker could aid with earlier diagnosis of breast cancer metastasis

One woman is diagnosed with breast cancer every fourteen seconds somewhere across the globe - based on data showing that an approximate 2.3 million women worldwide were newly diagnosed with breast cancer in 2020.

16 Aug 2022

Researchers develop Cluster-Wells to facilitate the study of circulating tumor cells

Cancer spreads via circulating tumor cells (CTCs) that travel through the blood to other organs, and they are nearly impossible to track. Now, researchers at the Georgia Institute of Technology have found a detection method that could revolutionize cancer treatment by showing how cancers metastasize and what stage they are. This could lead to earlier and more targeted treatment, beginning with a simple blood test.

16 Aug 2022

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

Researchers around the world have been working for years on developing vaccines against different types of cancer, but without much success. Now, Tufts School of Engineering researchers think they have found one that does work. They have devised a method of targeting cancer in mice with a vaccine that is so strong and precise, it eliminates tumors and even prevents their recurrence.

16 Aug 2022

New method for 3D culture accurately quantifies how cancer cells generate forces to spread within tissue

Research to understand how cancers grow and spread has conventionally been done on two-dimensional, flat cultures of cells, which is very different to the three-dimensional structure of cells in the body.

12 Aug 2022

Scientists develop a smart contact lens that can capture and detect exosomes

Scientists from the Terasaki Institute for Biomedical Innovation (TIBI) have developed a contact lens that can capture and detect exosomes, nanometer-sized vesicles found in bodily secretions which have the potential for being diagnostic cancer biomarkers.

12 Aug 2022

Newly designed nanoparticles target the body’s immune cells to turn them against cancer

Scientists of the department of Advanced Organ Bioengineering and Therapeutics (Faculty of S&T, TechMed Centre) recently published a novel cancer immune therapy in the scientific journal Nature Communications.

11 Aug 2022

Novel model reveals how genomic instability arises in histologically benign tissue

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically, over time. This has been made possible using a new technique called spatial transcriptomics, which allows scientists to see what genetic changes take place without breaking up the tissue they're looking at.

11 Aug 2022

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression.

11 Aug 2022

Collagen XII likely to be a potential marker for patients at high risk of metastatic relapse

Collagen type XII plays a key role in regulating the organization of the tumor matrix, reveals a new study from the Garvan Institute of Medical Research. A team of scientists led by Associate Professor Thomas Cox, Head of the Matrix and Metastasis lab, also discovered that high levels of collagen XII can trigger breast cancer cells to spread from the tumor to other parts of the body, a process known as metastasis.

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Tumor News and Research

Discovery points to new drug targets that could prevent cancer spread

Researchers reveal details of two key transition points in the development of pancreatic tumors

Study shows encouraging results for robotic IVC thrombectomy

Scientists identify new driver for rare type of liver cancer

Researchers visualize antigen-bound T-cell receptor at atomic resolution

New strategies to enhance the survival of children with neuroblastoma

Study contributes to better understanding of the changes in kinase activity in renal cell carcinoma

UW cardiologists employ catheter-delivered device to retrieve a benign tumor from the heart

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

Non-invasive biomarker could aid with earlier diagnosis of breast cancer metastasis

Researchers develop Cluster-Wells to facilitate the study of circulating tumor cells

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

New method for 3D culture accurately quantifies how cancer cells generate forces to spread within tissue

Scientists develop a smart contact lens that can capture and detect exosomes

Newly designed nanoparticles target the body’s immune cells to turn them against cancer

Novel model reveals how genomic instability arises in histologically benign tissue

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

Collagen XII likely to be a potential marker for patients at high risk of metastatic relapse

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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