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Bacteria causing urinary tract infections can originate in meat-production chain

In young women, Staphylococcus saprophyticus is a main cause of urinary tract infections (UTI), reaching 20% prevalence. Understanding the epidemiology of this microorganism can help identify its origin, distribution, causes, and risk factors.

8 Jun 2021

New drug shows promise against lung cancer caused by genetic mutation

The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial.

8 Jun 2021

Distinct spike protein mutations in SARS-CoV-2 variant in Russia

Additionally, a novel variant has recently been characterized by researchers from Russia in the journal Viruses. The variant, first discovered in January 2021 in Northwest Russia, is characterized by distinct spike protein mutations.

7 Jun 2021

International travelers may pick up destination-specific antimicrobial resistance genes, study reveals

Travelers abroad may pick up bacteria and other vectors containing genes conferring antimicrobial resistance which remain in the gut when returning to their home country, according to a study published in Genome Medicine.

7 Jun 2021

The genetic diversity of SARS-CoV-2 in the USA

In a research paper recently uploaded to the preprint server medRxiv by Capoferri et al. (June 4th, 2021), the genetic diversity of SARS-CoV-2 through each phase is examined in detail using publicly available genomic data available from before 2021, highlighting the need to continuously track and assess the evolution of the virus to ensure the future efficacy of the currently available vaccines.

7 Jun 2021

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

In a recent research paper currently available on the bioRxiv* preprint server, scientists in the US used genome-scale CRISPR knockout screens to identify factors that promote infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), revealing the potential for broad-spectrum activity across the coronavirus family.

7 Jun 2021

Risk of SARS-CoV-2 transmission aboard aircraft is low: A review of evidence

Researchers in Romania, the UK, and Canada have systematically reviewed the evidence available on the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aboard aircraft.

7 Jun 2021

ERS Genomics and genOway enter CRISPR/Cas9 agreement

ERS Genomics Limited today announced a non-exclusive license agreement granting genOway past and future access to ERS Genomics’ CRISPR/Cas9 patent portfolio.

7 Jun 2021

International travelers often return home with new bacterial strains, confirms study

Carried like stowaways in the guts of international travelers, new and potentially deadly strains of antimicrobial resistant superbugs may be coming to a community near you, suggests new research from Washington University School of Medicine in St. Louis.

7 Jun 2021

Comparison of immunological profiles of SARS-CoV-2 variants

Mutations to the spike protein and receptor-binding domain are responsible for these changes in immunogenic profile, and in a paper recently uploaded to the open access journal Antibiotics by Ambrose et al. (May 6th, 2021) these mutations are correlated with various disease parameters by in silico methods, finding that particular features are responsible for the increased infectiousness and lesser disease severity observed in these lineages.

6 Jun 2021

SARS-CoV-2 genome analysis reveals new 'Mexican variant'

A research group of the Department of Pharmacy and Biotechnology of the University of Bologna analyzed more than one million SARS-CoV-2 genome sequences.

5 Jun 2021

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. c

5 Jun 2021

Gene offers some level of protection from severe Covid

The first evidence of a genetic link explaining why some people who catch Covid-19 don't become sick has been discovered.

5 Jun 2021

A lack of oversight for unproven stem cell interventions is a global public health problem

Authors are urging the WHO to establish an Exert Advisory Committee on Regenerative Medicine to provide harmony to the national regulations on the SCI industry.

4 Jun 2021

Study identifies new genetic variants that cause developmental disorders in children

Non-coding regions of DNA could hold the key to diagnosing developmental disorders in children, new research suggests.

4 Jun 2021

World Health Organization simplifies names of SARS-CoV-2 variants

Now, the World Health Organization (WHO) has assigned simple and easy-to-say labels for key variants of SARS-CoV-2 using letters of the Greek alphabet. The health agency selected these labels after a thorough review of many potential naming systems.

4 Jun 2021

NIH study identifies promising oral antiviral treatment for COVID-19

The experimental drug TEMPOL may be a promising oral antiviral treatment for COVID-19, suggests a study of cell cultures by researchers at the National Institutes of Health.

3 Jun 2021

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

A recent Science paper discusses the utilization of a previously reported synthetic Escherichia coli to produce virus-resistant synthetic polymers.

3 Jun 2021

Study shows how the physical nature of genome changes before and after cell differentiation

The organization of the human genome relies on physics of different states of matter - such as liquid and solid - a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes as cells transform to serve specific functions, point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders.

3 Jun 2021

Single mutation to bat virus spike protein allows cell entry using human ACE2

In a paper recently uploaded to the preprint server bioRxiv by Kirchhoff et al. (May 31st, 2021) it is demonstrated that a single mutation to the RaTG13 spike protein results in significantly greater affinity towards the human receptor, indicating that the presence of a positively charged amino group at this position better facilitates interaction with the human ACE2 receptor, and helping to identify other viruses with zoonotic potential.

3 Jun 2021

Genome News and Research

Bacteria causing urinary tract infections can originate in meat-production chain

New drug shows promise against lung cancer caused by genetic mutation

Distinct spike protein mutations in SARS-CoV-2 variant in Russia

International travelers may pick up destination-specific antimicrobial resistance genes, study reveals

The genetic diversity of SARS-CoV-2 in the USA

Genome-scale CRISPR screens pinpoint promising antiviral compounds against SARS-CoV-2

Risk of SARS-CoV-2 transmission aboard aircraft is low: A review of evidence

ERS Genomics and genOway enter CRISPR/Cas9 agreement

International travelers often return home with new bacterial strains, confirms study

Comparison of immunological profiles of SARS-CoV-2 variants

SARS-CoV-2 genome analysis reveals new 'Mexican variant'

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

Gene offers some level of protection from severe Covid

A lack of oversight for unproven stem cell interventions is a global public health problem

Study identifies new genetic variants that cause developmental disorders in children

World Health Organization simplifies names of SARS-CoV-2 variants

NIH study identifies promising oral antiviral treatment for COVID-19

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

Study shows how the physical nature of genome changes before and after cell differentiation

Single mutation to bat virus spike protein allows cell entry using human ACE2

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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