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Moderna announces initiation of Phase 1 study of its mRNA-1189 EBV vaccine candidate

Moderna, Inc., a biotechnology company pioneering messenger RNA therapeutics and vaccines, today announced the first participant has been dosed in the Phase 1 study of mRNA-1189, the Company's Epstein-Barr Virus vaccine candidate.

7 Jan 2022

Grouping tumors by 'immune archetypes' points the way to personalized immunotherapies

The UCSF researchers, led by first co-authors Alexis Combes, PhD, and Bushra Samad, MS, and senior author, Max Krummel, PhD, obtained tumor specimens from 78 UCSF clinicians, and surveyed 364 tumors biopsies from patients and categorized them into groups based on their immune microenvironment.

7 Jan 2022

Researchers study immune cell invasion process in living fruit fly embryos

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

6 Jan 2022

Study reinforces the link between microglia and some cases of brain disease

Certain subtle differences in DNA sequences are known to raise the chances a person may develop Alzheimer's or Parkinson's disease.

6 Jan 2022

Study identifies current mechanism of action behind reduced severity of Omicron variant COVID-19 infection

New research shows evidence that the Omicron variant is less severe compared to the Delta variant.

6 Jan 2022

Efficacy of COVID-19 convalescent plasma therapy in patients with hematological malignancies and COVID-19

Scientists recently demonstrated the efficacy of COVID-19 convalescent plasma therapy in improving the survival rate among patients with B-cell lymphoid malignancy and COVID-19.

5 Jan 2022

Oral bacteria-based SARS-CoV-2 vaccine platform

In a new study, researchers engineered the bacterial strain, Salmonella, to express differently-sized antigens to serve as vaccine platforms.

5 Jan 2022

Can the COVID-19 delta variant evade vaccine-induced immunity?

Can the COVID-19 delta variant evade vaccine-induced immunity? We spoke to Professor Brian J. Willett from the University of Glasgow to find out.

5 Jan 2022

Birth during the pandemic associated with slightly lower scores in infants' motor and social skills

Columbia researchers found that babies born during the pandemic's first year scored lower on a developmental screening test of social and motor skills at 6 months - regardless of whether their mothers had COVID during pregnancy - compared to babies born just before the pandemic.

4 Jan 2022

Scientists find that having one kind of autoimmune disease can lead to another

Researchers at the University of Colorado Anschutz Medical Campus have discovered that having one kind of autoimmune disease can lead to another.

4 Jan 2022

New Potocsnak Longevity Institute aims to extend human 'healthspan'

In the not-too-distant future, you'll be able to check into the Human Longevity Laboratory to find out how old you really are, physiologically speaking.

4 Jan 2022

Omicron spike-specific binding antibodies attenuate disease, despite increasing transmission

Researchers investigate the capacity of vaccine-induced antibodies to generate Fc-effector activity against the SARS-CoV-2 Omicron variant.

3 Jan 2022

Study reveals how online misinformation 'ticks' and suggests new strategy to stop it

Parenting communities on Facebook were subject to a powerful misinformation campaign early in the COVID-19 pandemic that pulled them closer to extreme communities and their misinformation, according to a new study published by researchers at the George Washington University.

3 Jan 2022

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

A new study used in silico approaches for designing a next-generation CD40-targeting vaccine, CD40.

31 Dec 2021

The use of monoclonal antibodies against infectious pathogens

Joshua Tan of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health wrote a review article in the journal DNA and Cell Biology about the role of monoclonal antibodies and briefly described a study on bispecific antibodies that neutralize SARS-CoV-2.

30 Dec 2021

Recombinant adjuvanted zoster vaccination associated with lower risk of COVID-19 diagnosis and hospitalization

A new study suggests that RZV may elicit durable innate immune responses in the elderly conferring heterologous protection against COVID-19. .

30 Dec 2021

SARS-CoV-2 infection can produce self-attacking autoantibodies

Infection with the virus that causes COVID-19 can trigger an immune response that lasts well beyond the initial infection and recovery - even among people who had mild symptoms or no symptoms at all, according to Cedars-Sinai investigators.

30 Dec 2021

Successful weight-loss intervention helps lower risk of severe complications from COVID-19

A Cleveland Clinic study shows that among patients with obesity, prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe complications from COVID-19 infection. The research was published in the journal JAMA Surgery.

30 Dec 2021

An integrated computational methodology for COVID drug prioritization

Researchers recently published a study in the journal Briefings in Bioinformatics wherein they integrated multiple bioinformatics and cheminformatics-based methods to prioritize drugs for the treatment of COVID-19.

29 Dec 2021

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

A new study found that the presence of a subset of antibodies with broad neutralizing activities against all circulating variants of concern in the three-dose vaccines' memory B-derived antibody repertoire suggests that the Omicron/future variants infection may elicit selective and rapid recall of humoral responses, conferring secondary protection directed by memory etched in the immune system.

29 Dec 2021

Immune System News and Research

Moderna announces initiation of Phase 1 study of its mRNA-1189 EBV vaccine candidate

Grouping tumors by 'immune archetypes' points the way to personalized immunotherapies

Researchers study immune cell invasion process in living fruit fly embryos

Study reinforces the link between microglia and some cases of brain disease

Study identifies current mechanism of action behind reduced severity of Omicron variant COVID-19 infection

Efficacy of COVID-19 convalescent plasma therapy in patients with hematological malignancies and COVID-19

Oral bacteria-based SARS-CoV-2 vaccine platform

Can the COVID-19 delta variant evade vaccine-induced immunity?

Birth during the pandemic associated with slightly lower scores in infants' motor and social skills

Scientists find that having one kind of autoimmune disease can lead to another

New Potocsnak Longevity Institute aims to extend human 'healthspan'

Omicron spike-specific binding antibodies attenuate disease, despite increasing transmission

Study reveals how online misinformation 'ticks' and suggests new strategy to stop it

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

The use of monoclonal antibodies against infectious pathogens

Recombinant adjuvanted zoster vaccination associated with lower risk of COVID-19 diagnosis and hospitalization

SARS-CoV-2 infection can produce self-attacking autoantibodies

Successful weight-loss intervention helps lower risk of severe complications from COVID-19

An integrated computational methodology for COVID drug prioritization

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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