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New ways to control fever-induced seizures

When your body cranks up the heat, it's a sign that something's wrong and a fever is designed to help fight off the infection.

24 Aug 2007

Scientists investigate initial molecular mechanism that triggers neuronal firing

Carnegie Mellon University chemists have solved a decade-long molecular mystery that could eventually help scientists develop drug therapies to treat a variety of disorders, including epilepsy and Alzheimer's disease.

24 Aug 2007

All eukaryotic kinases share 1 common set of substrates

Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death.

24 Aug 2007

Rapamycin study is first stage in development of new treatment

Rapamycin isn't your ordinary potential anti-cancer drug…It had a long and somewhat exotic history before undergoing preclinical (laboratory-based) studies at St. Jude as part of a national Pediatric Preclinical Testing Program (PPTP) investigation of its anticancer activity.

23 Aug 2007

Cancer stem cell scientists get $1.7 million to develop new leukemia drugs

"Modern cancer treatments fail to get to the root of the cancer - the stem cells - which is why many cancers recur despite aggressive treatment."

23 Aug 2007

More informative labels proposed for sunscreens

The Food and Drug Administration (FDA) in the United States has proposed new regulation governing the development and testing of sunscreens; they also want warnings on the labels about the risk of skin cancer linked to sun exposure.

23 Aug 2007

Antipsychotic drug Risperdal approved for use in children

The Food and Drug Administration (FDA) in the U.S. has given approval for the antipsychotic drug Risperdal to be used to treat schizophrenia and bipolar disorder in children and teenagers.

23 Aug 2007

South African experts say food no substitute for medical drugs in AIDS and TB

A report by the Academy of Science of South Africa has stated that there is no evidence to support the theory that a healthy diet is a substitute for medical drugs when it comes to treating HIV/AIDS and tuberculosis (TB).

22 Aug 2007

Antitumour drugs impede DNA uncoiling by topoisomerase I

The annoying bulges of an overwound telephone cord that shorten its reach and limit a caller's motion help explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators led by Mary-Ann Bjornsti, Ph.D., at St. Jude Children’s Research Hospital, and Nynke Dekker, Ph.D., at Delft Technology University.

22 Aug 2007

Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy

A new targeted drug delivery method, which combines two nanoparticles into one larger one, uses ultrasound to image tumors and release the anticancer drug doxorubicin from "nanobubbles" into the same tumors.

22 Aug 2007

Geographical variation in the prevalence of problematic substance use in Canada

If you think the big cities of Toronto and Montreal have the highest rate of alcohol and drug use problems, think again.

22 Aug 2007

Insulin pens may offer diabetics substantial savings

Diabetics who need to switch from oral medications to insulin could reduce their annual healthcare costs up to $17,000 by using an insulin pen instead of a syringe to deliver their daily dose of medication.

22 Aug 2007

Pomegranate juice does not impair clearance of oral or intravenous Midazolam

A study from the Tufts University School of Medicine published in the Journal of Clinical Pharmacology finds that pomegranate juice does not interact with oral or intravenous medication, contrary to previous information.

22 Aug 2007

Sewage reveals community-wide illegal drug use

Public health officials may soon be able to flush out more accurate estimates on illegal drug use in communities across the country thanks to screening test described at the 234 th national meeting of the American Chemical Society, the world's largest scientific society.

22 Aug 2007

High altitude pulmonary oedema

Experts at the University are studying an illness known as HAPE (high altitude pulmonary oedema), which causes fluid to build up in the lungs can and can occur from as low as 2,500 metres, affecting people of all age groups and fitness levels.

22 Aug 2007

Natural antimicrobial agents for food safety

Two items high on the list of public concerns are the need for greater food safety and a growing demand for natural or organic food products.

22 Aug 2007

Genetics determine optimal drug dose of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood , the journal of the American Society of Hematology.

22 Aug 2007

Cranberries, chemo and ovarian cancer

Compounds in cranberries may help improve the effectiveness of platinum drugs that are used in chemotherapy to fight ovarian cancer, researchers have found in a laboratory study that will be reported at the 234 th national meeting of the American Chemical Society.

22 Aug 2007

Call for improved treatments of stroke

A coalition of physicians representing a wide range of medical specialties has issued a call to action to improve the treatment of stroke.

22 Aug 2007

AIDS Vaccine Advocacy Coalition receives $14 million from Gates Foundation

The AIDS Vaccine Advocacy Coalition (AVAC) announced today at the AIDS Vaccine 2007 Conference that it has received a five-year, $14 million grant from the Bill & Melinda Gates Foundation to create a new international HIV Prevention Research Advocacy Network.

21 Aug 2007