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Repeated mRNA vaccinations enhance mucosal antibody production

During the COVID pandemic, many of us have received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.

23 Oct 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

HER2-postive breast cancer drugs show promise for bile duct cancer treatment

Drugs designed to target HER2-postive breast cancer could also benefit some patients with bile duct cancer, according to results of a patient trial to be presented on Thursday at the 36th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain.

23 Oct 2024

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy - similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis - also may be an effective treatment strategy for heart failure.

23 Oct 2024

NIH launches precision medicine trial to test new treatments for myeloid cancers

The National Institutes of Health (NIH) has launched a proof-of-concept precision medicine clinical trial to test new treatment combinations targeting specific genetic changes in the cancer cells of people with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).

23 Oct 2024

WHO faces challenges in delivering aid amid intensifying hostilities in Gaza

On 21 October, 14 patients and 10 caregivers were transferred from Kamal Adwan in North Gaza to Al-Shifa Hospital in Gaza City during a high-risk, WHO-led joint mission, amid intense hostilities and access restrictions.

23 Oct 2024

Scurvy may be making a comeback amid economic strain

The scourge of scurvy, which is caused by vitamin C deficiency, may be re-emerging amid the cost of living crisis and the rise in weight loss (bariatric) surgery, suggest doctors in the journal BMJ Case Reports after treating a middle-aged man with the condition.

22 Oct 2024

Study links schizophrenia to increased risk of sudden cardiac death

The lifetime risk of an unexpected and sudden death from a cardiovascular cause in the absence of pre-existing heart disease - known as sudden cardiac death - is more than 4 times higher for people with schizophrenia than it is for the general population, indicates Danish research published online in the journal Heart.

22 Oct 2024

Floor swabbing offers new insights for COVID-19 monitoring

COVID-19 is here to stay. As restrictions and human testing have waned, new research is tackling the challenge of how we can monitor, predict, and prevent cases and outbreaks of COVID-19, especially among vulnerable groups like hospitalized patients.

22 Oct 2024

Physical tests offer prognostic insights for lung cancer patients

A study of patients with metastatic lung cancer by researchers based in Brazil and the United States has found that their performance in simple physical tests such as sitting down, standing and walking can help physicians arrive at a prognosis and approach to treatment.

22 Oct 2024

Type 2 diabetes patients may benefit from reduced carbohydrate intake

Adults with type 2 diabetes on a low-carbohydrate diet may see benefits to their beta-cell function allowing them to better manage their disease and possibly discontinue medication, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

22 Oct 2024

Study finds connection between air pollution and childhood peanut allergies

Exposure to higher levels of air pollution as a baby is linked to having a peanut allergy throughout childhood, according to a new study.

22 Oct 2024

Mothering over meds: Docs say common treatment for opioid-exposed babies isn’t necessary

On learning last year she was pregnant with her second child, Cailyn Morreale was overcome with fear and trepidation.

22 Oct 2024

Ultra-processed foods linked to liver disease and insulin resistance in obese children

Ultra-processed food consumption in obese adolescents is linked to insulin resistance and liver disease, stressing the need for improved dietary interventions.

22 Oct 2024

Mediterranean diet lowers risk of multiple heart and metabolic diseases

Adhering to the Mediterranean diet reduces the risk of developing a second cardiometabolic disease, especially over shorter follow-up periods, with social class influencing the diet’s impact.

21 Oct 2024

Rising asthma rates in sub-Saharan Africa linked to urbanization and lack of care

Rapid urbanization and population growth in sub-Saharan Africa has increased the incidence of asthma in young people, but the lack of diagnosis and care means that many young people are suffering from untreated symptoms of asthma, according to research from Queen Mary University of London.

21 Oct 2024

Black patients face higher risks following coronary artery bypass grafting

Despite advances in cardiovascular medicine, Black patients are 22% more likely than white patients to die in the hospital after coronary artery bypass grafting (CABG) surgery, according to a study of more than 1 million patients presented at the ANESTHESIOLOGY 2024 annual meeting.

21 Oct 2024

Methadone more effective than buprenorphine in reducing treatment discontinuation

People with opioid use disorder in British Columbia who received methadone had a 37–40 per cent lower rate of treatment discontinuation compared with those who received buprenorphine/naloxone.

21 Oct 2024

Research reveals AI's potential to transform hospital reporting processes

A pilot study led by researchers at University of California San Diego School of Medicine found that advanced artificial intelligence (AI) could potentially lead to easier, faster and more efficient hospital quality reporting while retaining high accuracy, which could lead to enhanced health care delivery.

21 Oct 2024

Mental health problems lead to greater productivity loss than other chronic conditions

Depression and other mental health issues reduce the number of productivity-adjusted life years (PALYs) more than musculoskeletal diseases or cardiovascular diseases, according to a recent joint study by the University of Eastern Finland, the Finnish Social Insurance Institution (Kela), and Monash University in Australia.

21 Oct 2024